Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia

Acar, Tarık; Cander, Başar; ergin, mehmet; dikmetaş, cesareddin; Kocak, Sedat

Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia

Tarık ACAR, (Ordu Üniversitesi Eğitim ve Araştırma Hastanesi, Ordu, Türkiye)

Sedat KOÇAK, (Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Acil Tıp Anabilim Dalı, Konya, Türkiye)

Başar CANDER, (Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Acil Tıp Anabilim Dalı, Konya, Türkiye)

Mehmet ERGİN, (Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Acil Tıp Anabilim Dalı, Konya, Türkiye)

Cesareddin DİKMETAŞ (Ordu Üniversitesi Eğitim ve Araştırma Hastanesi, Ordu, Türkiye)

Turkish Journal of Medical Sciences

2 1

Yıl: 2016 Cilt: 46 Sayı: 1 Sayfa Aralığı: 120 - 125 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia

Öz:

Background/aim: The purpose of this experimental study was to investigate the role of lipoprotein-associated phospholipase-A2(LpPLA2 ) in the diagnosis of acute mesenteric ischemia (AMI) in the early stage. Materials and methods: Twenty-seven New Zealand rabbits were randomly divided into 3 groups in this study. Blood specimens were obtained from the groups at hours 0, 1, 3, and 6. Using the blood samples drawn from all groups, Lp-PLA2 and C-reactive protein (CRP) parameters were investigated. Results: There was a significant rise in the levels of both Lp-PLA2 and CRP starting at hour 1 (P < 0.05) (hour 1; Lp-PLA2 , P = 0.003) in the ischemia group. In the sham group, the levels of Lp-PLA2 and CRP started to rise at hour 3 (P < 0.05) (hour 3; Lp-PLA2 , P = 0.011). At hour 6 of ischemia, the area under the ROC curve was 100%, and the cut-off value of 63.91 ng/mL revealed a sensitivity of 88% and a specificity of 100% for Lp-PLA2 . Conclusion: These findings showed the role of serum Lp-PLA2 and CRP levels in the early diagnosis of AMI. Thus, further studies are needed to describe the role of Lp-PLA2 in the early diagnosis of AMI.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Acar T, Kocak S, Cander B, ergin m, dikmetaş c (2016). Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. , 120 - 125.
Chicago	Acar Tarık,Kocak Sedat,Cander Başar,ergin mehmet,dikmetaş cesareddin Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. (2016): 120 - 125.
MLA	Acar Tarık,Kocak Sedat,Cander Başar,ergin mehmet,dikmetaş cesareddin Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. , 2016, ss.120 - 125.
AMA	Acar T,Kocak S,Cander B,ergin m,dikmetaş c Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. . 2016; 120 - 125.
Vancouver	Acar T,Kocak S,Cander B,ergin m,dikmetaş c Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. . 2016; 120 - 125.
IEEE	Acar T,Kocak S,Cander B,ergin m,dikmetaş c "Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia." , ss.120 - 125, 2016.
ISNAD	Acar, Tarık vd. "Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia". (2016), 120-125.

APA	Acar T, Kocak S, Cander B, ergin m, dikmetaş c (2016). Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. Turkish Journal of Medical Sciences, 46(1), 120 - 125.
Chicago	Acar Tarık,Kocak Sedat,Cander Başar,ergin mehmet,dikmetaş cesareddin Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. Turkish Journal of Medical Sciences 46, no.1 (2016): 120 - 125.
MLA	Acar Tarık,Kocak Sedat,Cander Başar,ergin mehmet,dikmetaş cesareddin Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. Turkish Journal of Medical Sciences, vol.46, no.1, 2016, ss.120 - 125.
AMA	Acar T,Kocak S,Cander B,ergin m,dikmetaş c Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. Turkish Journal of Medical Sciences. 2016; 46(1): 120 - 125.
Vancouver	Acar T,Kocak S,Cander B,ergin m,dikmetaş c Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia. Turkish Journal of Medical Sciences. 2016; 46(1): 120 - 125.
IEEE	Acar T,Kocak S,Cander B,ergin m,dikmetaş c "Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia." Turkish Journal of Medical Sciences, 46, ss.120 - 125, 2016.
ISNAD	Acar, Tarık vd. "Liporotein-associated phospholipase-A2 can be a diagnostic marker inthe early stage diagnosis of acute mesenteric ischemia". Turkish Journal of Medical Sciences 46/1 (2016), 120-125.