Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria

Okmen, Gulten; Ceylan, Ozgur; Ugur, Aysel

Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria

Ozgur CEYLAN, (Muğla Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Muğla, Türkiye)

Gülten ÖKMEN, (Muğla Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Muğla, Türkiye)

Aysel UĞUR (Muğla Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Muğla, Türkiye)

EurAsian Journal of BioSciences (elektronik)

8 0

Yıl: 2008 Cilt: 0 Sayı: 2 Sayfa Aralığı: 73 - 82 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria

Öz:

Bu calismanin amaci toprakta yaygin olarak bulunan ve antibiyotik ureticileri olarak bilinen Streptomyces'lerin in vitro antimikrobiyal aktiviteleridir. Turkiye, Mugla'daki farkli alanlardan Streptomyces izolatlari, coklu antibiyotige direncli Staphylococcus aureus ve Stenotrophomonas maltophilia'yi kapsayan on bes mikroorganizma uzerinde inhibitor aktiviteleri degerlendirilmistir. Test mikroorganizmalarinin en az ikisine karsi antimikrobiyal aktivite gosteren on bes Streptomycete izolati geleneksel metodlar ile karakterize edilmistir. Sonuclar bes izolatin metisiline direncli Staphylococcus aureus (MRSA)'u kapsayan S. aureus suslarina karsi yuksek derecede aktif olduklarini gostermektedir. On iki Streptomycete izolati Candida albicans'a karsi antikandidal aktivite gostermistir. On izolat 30 mm captan daha fazla inhibisyon zonlu yuksek aktivitelidir. Izolatlarin cogu Gram negatif test bakterilerinin gelisimini inhibe etmistir. Sekiz izolat S. maltophilia MU64 uzerinde antibakteriyal aktivite gostermistir. Bunlarin ikisinin inhibisyon zonlari S. maltophilia icin 30 mm'den daha yuksektir.

Anahtar Kelime: Staphylococcus aureus antimikrobiyal özellikler antibakteriyel özellikler antibiyotiklere duyarlılık Candida albicans direnç antibiyotikler Stenotrophomonas maltophilia Streptomyces izolasyon

Konular: Biyoloji

Antibiyotik dirençli bakterilere karşı aktif antibiyotik kaynağı olarak toprak Streptomyces'lerinin izolasyonu

Öz:

Abstract The focus of this study was the in vitro antimicrobial activities of Streptomycetes, bacteria commonly found in soil and known antibiotic-producers. Streptomycete isolates obtained from different fields in Muðla, Turkey were evaluated for their inhibitory activities on seven microorganisms including multiple antibiotic resistant Staphylococcus aureus and Stenotrophomonas maltophilia. Fifteen Streptomycete isolates which exhibited antimicrobial activity against at least two of the test organisms were characterized by conventional methods. The results indicated that five isolates were highly active against S. aureus strains including meticillin resistant Staphylococcus aureus (MRSA). Twelve Streptomycete isolates showed anticandidal activity against Candida albicans. Ten isolates were highly active with an inhibition zone more than 30 mm in diameter. Most of the isolates inhibited growth of the Gram negative bacteria tested. Eight isolates showed antibacterial activity on S. maltophilia MU64. The inhibition zones of two were higher than 30 mm for S. maltophilia.

Anahtar Kelime: antibiotics Stenotrophomonas maltophilia Streptomyces isolation Staphylococcus aureus antimicrobial properties antibacterial properties antibiotic sensivity Candida albicans resistance

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

Abbanat D, Macielag M, Bush K (2003) Novel antibacterial agents for the treatment of serious Gram-positive infections. Expert Opinion on Investigational Drugs 12, 379-399.
Alanis AJ (2005) Resistance to antibiotics: are we in the post-antibiotic era? Archives of Medical Research 36, 697-705.
Al-Masaudi SB, Day MJ, Russell AD (1991) Antimicrobial resistance and gene transfer in Staphylococcus aureus. Journal of Applied Bacteriology 70, 270-290. Anonymous (2004) Brief report: vancomycin-resistant Staphylococcus aureus-New York. MMWR 53, 322-323.
Aslan B (1999) Studies on isolation, characterization and antibiotic production of Streptomyces species. PhD thesis, Cukurova University, Institute of Science, Adana.
Barrett CT, Barrett JF (2003) Antibacterials: are the new entries enough to deal with the emerging resistance problems? Current Opinion in Biotechnology 14, 621-626.
Barsby T, Kelly MT, Gagne SM (2001) Bogorol A produced in culture by a marine Bacillus sp. reveals a novel template for cationic peptide antibiotics. Organic Letters 3, 3, 437-440.
Beovic B (2006) The issue of antimicrobial resistance in human medicine. International Journal of Food Microbiology 112, 3, 280-287.
Bozdogan B, Esel D, Whitener C (2003) Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus strain isolated at the Hershey Medical Center. Journal of Antimicrobial Chemotherapy 52, 864-868.
Chang S, Sievert DM, Hageman JC (2003) Infection with vancomycin resistant Staphylococcus aureus containing the vanA resistance gene. The New England Journal of Medicine 348, 1342-1347.
Crandall LW, Hamil RL (1986) Antibiotics produced by Streptomyces: major structural classes. In: Queener SW, Day LE (eds), The bacteria, Vol. 9, Academic Press, Orlando, Fla, 355-401.
Cross T (1989) Growth and examination of actinomycetes some guidelines. In: Bergey's Manual of Systematic Bacteriology, Vol. 4, Williams and Wilkins Company, Baltimore, 2340-2343.
Dancer SJ (2004) How antibiotics can make us sick: the less obvious adverse effects of antimicrobial chemotherapy. The Lancet Infectious Diseases 4, 611-619.
Denizci AA (1996) A study on the detection and production of antibacterial antibiotics from Actinomycetes which isolated from the soils of Aegean and Eastern Black Sea regions of Turkey. PhD thesis, Ege University, Institute of Science, Izmir.
Denton M, Kerr KG (1998) Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia. Clinical Microbiology Reviews 11, 57-80.
Enright MC (2003) The evolution of a resistant pathogen-the case of MRSA. Current Opinion in Pharmacology 3, 5, 474-479.
Fisher MC, Long SS, Roberts EM (1981) Pseudomonas maltophilia bacteremia in children undergoing open heart surgery. The Journal of the American Medical Association 246, 1471-1474.
Goodfellow M (1989) Suprageneric classification of Actinomycetes. In: Bergey's Manual of Systematic Bacteriology, Vol. 4, Williams and Wilkins Company, Baltimore, 2333-2339.
Gould IM (2005) The clinical significance of methicillin-resistant Staphylococcus aureus. Journal of Hospital Infection 61, 277-282.
Hajjeh RA, Rheingold A, Weil A, Shutt K, Schuhat A, Perkins BA (1999) Toxic shock syndrome in the United States, 1979-1996. Emerging Infectious Diseases 5, 807-810.
Hiramatsu K, Hanaki H, Ino T, Yabuta K, Oguri T, Tenover FC (1997) Methicillin- resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. The Journal of Antimicrobial Chemotherapy 40, 135-136.
Hiramatsu K (1998) Vancomycin resistance in Staphylococci. Drug Resist Updates 1, 135-150.
Hugh R, Ryschenkow E (1961) Pseudomonas maltophilia, an alcaligenes-like species. Journal of General Microbiology 26, 123-132.
Jevitt LA, Smith AJ, Williams PP, Raney PM, McGowan JE, Tenover FC (2003) In vitro activities of daptomycin, linezolid, and quinupristin-dalfopristin against a challenge panel of Staphylococci and Enterococci, including vancomycin-intermediate Staphylococcus aureus and vancomycin- resistant Enterococcus faecium. Microbial Drug Resistance 9, 389-393.
Kloos WE, Bannerman TL (1995) Staphylococcus and Micrococcus. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds), Manual of Clinical Microbiology, 6th ed, ASM Press, Washington DC, 282-298.
Korn-Wendisch F, Kutzner HJ (1992) The family Streptomycetaceae. In: Balows A, Truper HG, Dworkin M, Harder W, Schleifer KH (eds), The prokaryotes, Springer-Verlag, New York, 921-995.
Krueger TS, Clark EA, Nix DE (2001) In vitro susceptibility of Stenotrophomonas maltophilia to various antimicrobial combinations. Diagnostic Microbiology and Infectious Disease 41, 71-78.
Lechevalier HA (1989) The actinomycetes ill, a practical guide to generic identification of Actinomycetes. Bergey's Manual of Systematic Bacteriology, Vol. 4, Williams and Wilkins Company, Baltimore, 2344-2347.
Levy SB (2002) The antibiotic paradox: how misuse of antibiotics destroys their curative powers. 2nd (ed), Perseus Books, Boston.
Levy SB, Marshall B (2004) Antibacterial resistance worldwide: causes, challenges and responses. Nature Medicine 10, 122-129.
Livermore DM (2003) Bacterial resistance: origins, epidemiology and impact. Clinical Infectious Diseases 36, 11-23.
Liu PL, Lau YJ, Hu BS, Shyr JM, Shi ZY, Tsai WS, Lin YH, Tseng CY (1995) Comparison of susceptibility to extended-spectrum ß-lactam antibiotics and ciprofloxacin among gramnegative bacilli isolated from intensive care units. Diagnostic Microbiology and Infectious Disease 22, 285- 291.
Locci R (1989) Streptomyces and related genera. Bergey's Manual of Systematic Bacteriology. Vol. 4, Williams and Wilkins Company, Baltimore, 2451-2508.
Lyczak JB, Cannon CL, Pier GB (2000) Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes and Infection 2, 9, 1051-1060.
Lyon BR, Skurray R (1987) Antimicrobial resistance of Staphylococcus aureus: genetic basis. Microbiological Reviews 51, 88-134.
Madigan MT, Martinko JM, Parker J (1997) Antibiotics: isolation and characterization. In: Brock Biology of Microorganisms, 8th (ed), Prentice-Hall International Inc. New Jersey, 440-442.
Meka VG, Gold HS (2004) Antimicrobial resistance to linezolid. Clinical Infectious Diseases 39,1010-1015.
Miyadoh S (1993) Research on antibiotic screening in Japan over the last decade: A producing microorganisms approach. Actinomycetologica 9, 100-106.
Nathwani D (2005) Tigecycline: clinical evidence and formulary positioning. International Journal of Antimicrobial Agents 25, 185-192.
Nonomura H (1974) Key for classification and identification of 458 species of the Streptomyces included in ISP. Journal of Fermentation Technology 52, 78-92.
Obritsch MD, Fish DN, MacLaren R, Jung R (2004) National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from Intensive Care Unit Patients from 1993 to 2002. Antimicrobial Agents and Chemotherapy 48, 4606-4610. Oskay M, Tamer AU, Azeri C (2004) Antibacterial activity of some Actinomycetes isolated from farming soils of Turkey. African Journal of Biotechnology 3, 9, 441- 446.
Palleroni NJ, Bradbury JF (1993) Stenotrophomonas, a new bacterial genus for Xanthomonas maltophilia (Hugh 1980) Swings et al. 1983. International Journal of Systematic Bacteriology 43, 606-609.
Paterson DL, Ko WC, Von Gottberg A, Mohapatra S, Casellas JM, Goessens H, Mulazimoglu L, Trenholme G, Klugma KP, Bonomo RA, Rice LB, Wagener MM, McCormack JG, Yu VL (2004) International prospective study of Klebsiella pneumoniae bacteremia: implications of extendedspectrum beta-lactamase production in nosocomial infections. Annals of Internal Medicine 140, 26-32.
Prauser H (1964) Aptness and application of colour for exact description of colours of Streptomyces. Zeitschrift für allgemeine Mikrobiologie 4, 95-98.
Projan S (2002) New (and not so new) antibacterial targets- from where and when will the novel drugs come? Current Opinion in Pharmacology 2, 513-522.
Robin T, Janda JM (1996) Pseudo-, Xantho-, Stenotrophomonas maltophilia: an emerging pathogen in search of a genus. Clinical Microbiology Newsletter 18, 2, 9- 13.
Rubin RJ, Harrington CA, Poon A, Dietrich K, Greene JA, Moiduddin A (1999) The economic impact of Staphylococcus infection in New York City hospitals. Emerging Infectious Diseases 5, 9-17.
Saiman L, Chen Y, Gabriel PS, Knirsch C (2002) Synergistic activities of macrolide antibiotic against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis. Antimicrobial Agents and Chemotherapy 46, 4, 1105-1107.
Sahin N, Ugur A, (2003) Investigation of the antimicrobial activity of some Streptomyces isolates. Turkish Journal of Biology 27, 79-84.
Shirling EB, Gottlieb D (1966) Methods, classification, identification and description of genera and species. Vol. 2, The Williams and Wilkins Company, Baltimore, 61-292.
Skaehill P (2000) Management of Stenotrophomonas maltophilia infections. The Consult Pharmacist 15, 74-76.
Spizek J, Tichy P (1995) Some aspects of overproduction of secondary metabolites. Folia Microbiological 40, 43-50.
Swings J, Devos M, Van der Mooter M, De Ley J (1983) Transfer of Pseudomonas maltophilia Hugh 1981 to the genus Xanthomonas as Xanthomonas maltophilia (Hugh 1981) comb. nov. International Journal of Systematic Bacteriology 33, 409-413.
Tanaka YT, Mura SO (1993) Agro active compounds of microbial origin. Annual Review of Microbiology 47, 57-87.
Todd JK (1998) Toxic shock syndrome. Clinical Microbiology Reviews 1, 432-446.
Ugur A, Ceylan O (2003) Occurrence of resistance to antibiotics, metals, and plasmids in clinical strains of Staphylococcus spp. Archives of Medical Research 34, 130-136.
Urban C, Segal-Maurer S, Rahal JJ (2003) Considerations in control and treatment of nosocomial infections due to multi-drug resistant Acinetobacter baumannii. Clinical Infectious Diseases 36, 1268-1274.
Vartivarian S, Anaissie E, Bodey G, Sprigg H, Rolston K (1994) A changing pattern of susceptibility of Xanthomonas maltophilia to antimicrobial agents: implications for therapy. Antimicrobial Agents and Chemotherapy 38, 624- 627.
Waksman SA (1961) The Actinomycetes resistant bacteria. Journal of Arid Environments 53, 365-371.
Wenzel RP (2004) The antibiotic pipeline- challenges, costs, and values. New England Journal of Medicine 351, 523-526.
Willett HP (1992) Staphylococcus. In: Joklik WK, Willett HP, Amos DB, Wilfert CM (eds), Zinsser Microbiology, 20th ed., Norwalk, Appleton and Lange, 401-416.
Williams ST, Goodfellow M, Alderson G, Wellington EMH, Sneath PHA, Sackin MJ (1983a) Numerical classification of Streptomyces and related genera. Journal of General Microbiology 129, 1743-1813.
Williams ST, Goodfellow M, Wellington EMH, Vickers JC, Alderson G, Sneath PHA, Sackin MJ, Mortimer AM (1983b) A probability matrix for identification of Streptomyces. Journal of General Microbiology 129, 1815-1830.
Williams ST, Goodfellow M, Alderson G (1989) Genus Streptomyces Waksman and Henrici 1943, 339AL. In: Williams ST, Sharpe ME, Holt JG (eds.) Bergey's Manual of Systematic Bacteriology, Vol. 4, Williams and Wilkins, Baltimore, 2452-2492.

APA	Ceylan O, Okmen G, Ugur A (2008). Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. , 73 - 82.
Chicago	Ceylan Ozgur,Okmen Gulten,Ugur Aysel Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. (2008): 73 - 82.
MLA	Ceylan Ozgur,Okmen Gulten,Ugur Aysel Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. , 2008, ss.73 - 82.
AMA	Ceylan O,Okmen G,Ugur A Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. . 2008; 73 - 82.
Vancouver	Ceylan O,Okmen G,Ugur A Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. . 2008; 73 - 82.
IEEE	Ceylan O,Okmen G,Ugur A "Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria." , ss.73 - 82, 2008.
ISNAD	Ceylan, Ozgur vd. "Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria". (2008), 73-82.

APA	Ceylan O, Okmen G, Ugur A (2008). Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. EurAsian Journal of BioSciences (elektronik), 0(2), 73 - 82.
Chicago	Ceylan Ozgur,Okmen Gulten,Ugur Aysel Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. EurAsian Journal of BioSciences (elektronik) 0, no.2 (2008): 73 - 82.
MLA	Ceylan Ozgur,Okmen Gulten,Ugur Aysel Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. EurAsian Journal of BioSciences (elektronik), vol.0, no.2, 2008, ss.73 - 82.
AMA	Ceylan O,Okmen G,Ugur A Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. EurAsian Journal of BioSciences (elektronik). 2008; 0(2): 73 - 82.
Vancouver	Ceylan O,Okmen G,Ugur A Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria. EurAsian Journal of BioSciences (elektronik). 2008; 0(2): 73 - 82.
IEEE	Ceylan O,Okmen G,Ugur A "Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria." EurAsian Journal of BioSciences (elektronik), 0, ss.73 - 82, 2008.
ISNAD	Ceylan, Ozgur vd. "Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria". EurAsian Journal of BioSciences (elektronik) 2 (2008), 73-82.