Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study

Gülşah AŞIK, (Afyon Kocatepe Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Afyonkarahisar, Türkiye)
Mehmet ÖZDEMİR, (Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya, Türkiye)
Muhammet Güzel KURTOĞLU, (Konya Eğitim ve Araştırma Hastanesi, Mikrobiyoloji Anabilim Dalı, Konya, Türkiye)
Server YAĞCI, (Ankara Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye)
Lütfiye ÖKSÜZ, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)
Mustafa GÜL, (Sütçü İmam Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Kahramanmaraş, Türkiye)
Mücahide Esra KOÇOĞLU, (Abant İzzet Baysal Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)
EMEL SESLİ ÇETİN, (Süleyman Demirel Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Isparta, Türkiye)
Adnan SEYREK, (Yüzüncüyıl Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Van, Türkiye)
Mustafa BERKTAŞ, (Atatürk Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Erzurum, Türkiye)
Ahmet AYYILDIZ,
İhsan Hakkı ÇİFTCİ,
Turkish Journal of Medical Sciences
0 0
Yıl: 2014 Cilt: 44 Sayı: 6 Sayfa Aralığı: 1041 - 1046 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study

Öz:
Background/aim: &#946;-Lactamases are an important resistance mechanism in Acinetobacter baumannii. Pseudomonas extended-resistance (PER-1) type &#946;-lactamase producing strains have been reported from various geographic locations; however, PER-1 type &#946;-lactamases from Turkish hospitals have not been investigated extensively. The aim of this study was to determine the prevalence of PER-1 type &#946;-lactamases in A. baumannii isolates in various regions of Turkey. Materials and methods: A total of 763 clinical A. baumannii isolates were collected from 9 university hospitals and 2 state hospitals between 2008 and 2011. Molecular amplification of the OXA-51 gene from the A. baumannii genome was performed in order to verify identification of the species. Real-time polymerase chain reaction was used to detect blaPER-1 genes. Results: PER-1 was detected in 24.6% of the isolates. The annual frequencies of the PER-1 enzyme were detected as 52.2%, 35.9%, and 8.3% in 2008, 2009, and 2010, respectively. PER-1 prevalence decreased gradually over time. The differences observed in PER-1 prevalence among the regions of Turkey were statistically significant (chi-square test; P < 0.001). Conclusion: These data demonstrate that the frequency of detection of PER-1 type &#946;-lactamases in A. baumannii species has decreased in Turkey. However, the increased carbapenem resistance, together with multidrug resistance, has created a worrisome situation regarding this pathogen.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA AŞIK G, OZDEMIR M, KURTOĞLU M, YAĞCI S, ÖKSÜZ L, GÜL M, KOÇOĞLU M, SESLİ ÇETİN E, SEYREK A, BERKTAŞ M, AYYILDIZ A, ÇİFTCİ İ (2014). Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. , 1041 - 1046.
Chicago AŞIK Gülşah,OZDEMIR MEHMET,KURTOĞLU Muhammet Güzel,YAĞCI Server,ÖKSÜZ LÜTFİYE,GÜL MUSTAFA,KOÇOĞLU Mücahide Esra,SESLİ ÇETİN EMEL,SEYREK Adnan,BERKTAŞ Mustafa,AYYILDIZ Ahmet,ÇİFTCİ İHSAN HAKKI Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. (2014): 1041 - 1046.
MLA AŞIK Gülşah,OZDEMIR MEHMET,KURTOĞLU Muhammet Güzel,YAĞCI Server,ÖKSÜZ LÜTFİYE,GÜL MUSTAFA,KOÇOĞLU Mücahide Esra,SESLİ ÇETİN EMEL,SEYREK Adnan,BERKTAŞ Mustafa,AYYILDIZ Ahmet,ÇİFTCİ İHSAN HAKKI Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. , 2014, ss.1041 - 1046.
AMA AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. . 2014; 1041 - 1046.
Vancouver AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. . 2014; 1041 - 1046.
IEEE AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ "Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study." , ss.1041 - 1046, 2014.
ISNAD AŞIK, Gülşah vd. "Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study". (2014), 1041-1046.
APA AŞIK G, OZDEMIR M, KURTOĞLU M, YAĞCI S, ÖKSÜZ L, GÜL M, KOÇOĞLU M, SESLİ ÇETİN E, SEYREK A, BERKTAŞ M, AYYILDIZ A, ÇİFTCİ İ (2014). Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. Turkish Journal of Medical Sciences, 44(6), 1041 - 1046.
Chicago AŞIK Gülşah,OZDEMIR MEHMET,KURTOĞLU Muhammet Güzel,YAĞCI Server,ÖKSÜZ LÜTFİYE,GÜL MUSTAFA,KOÇOĞLU Mücahide Esra,SESLİ ÇETİN EMEL,SEYREK Adnan,BERKTAŞ Mustafa,AYYILDIZ Ahmet,ÇİFTCİ İHSAN HAKKI Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. Turkish Journal of Medical Sciences 44, no.6 (2014): 1041 - 1046.
MLA AŞIK Gülşah,OZDEMIR MEHMET,KURTOĞLU Muhammet Güzel,YAĞCI Server,ÖKSÜZ LÜTFİYE,GÜL MUSTAFA,KOÇOĞLU Mücahide Esra,SESLİ ÇETİN EMEL,SEYREK Adnan,BERKTAŞ Mustafa,AYYILDIZ Ahmet,ÇİFTCİ İHSAN HAKKI Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. Turkish Journal of Medical Sciences, vol.44, no.6, 2014, ss.1041 - 1046.
AMA AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. Turkish Journal of Medical Sciences. 2014; 44(6): 1041 - 1046.
Vancouver AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study. Turkish Journal of Medical Sciences. 2014; 44(6): 1041 - 1046.
IEEE AŞIK G,OZDEMIR M,KURTOĞLU M,YAĞCI S,ÖKSÜZ L,GÜL M,KOÇOĞLU M,SESLİ ÇETİN E,SEYREK A,BERKTAŞ M,AYYILDIZ A,ÇİFTCİ İ "Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study." Turkish Journal of Medical Sciences, 44, ss.1041 - 1046, 2014.
ISNAD AŞIK, Gülşah vd. "Detection of the frequency of PER-1 type extended-spectrum β-lactamase producing Acinetobacter baumannii clinical isolates in Turkey: a multicenter study". Turkish Journal of Medical Sciences 44/6 (2014), 1041-1046.
Sayfa Oluşturulma Tarihi
17-04-2024 5:44

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