Yıl: 2017 Cilt: 23 Sayı: 2 Sayfa Aralığı: 43 - 50 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı

Öz:
İdiyopatik intrakraniyal hipertansiyon (İİH) sekonder bir nedene bağlı olmayan kafa içi basınç artışıdır. Sıklıkla genç ve obez kadınlarda görülür. Baş ağrısı, görme problemleri ve pulsatil kulak çınlaması hastaları en çok hekime götüren şikayetlerdir. İİH heterojen bulgu ve belirtileri nedeniyle aile hekimlerini ve birçok branşı birlikte ilgilendirmektedir. Tedavisi gecikirse kalıcı morbidite yaratan bu hastalıkta her olgu için kişiye özgü bir tedavi planlanmalıdır. Bu yazıda son yayınlar çerçevesinde İİH'nin etiyopatogenezi ile birlikte tanı ve tedavisi gözden geçirilmiştir
Anahtar Kelime:

Konular: Nörolojik Bilimler

Idiopathic Intracranial Hypertension: Diagnosis and Therapeutic Approach

Öz:
Idiopathic intracranial hypertension (IIH) is a condition of increased intracranial pressure without a secondary etiology. IIH is seen frequently in young and obese women. Headache, vision problems, and pulsatile tinnitus are the most common symptoms that lead patients to physicians. IIH requires a multidisciplinary approach because it could create permanent morbidity and its treatment plan should be individualized for each patient. The aim of this review was to provide an updated overview of IIH’s pathogenesis, diagnostic criteria, and treatment strategies
Anahtar Kelime:

Konular: Nörolojik Bilimler
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • 1. McCluskey G, Mulholland DA, McCarron P, McCarron MO. Idiopathic Intracranial Hypertension in the Northwest of Northern Ireland: Epidemiology and Clinical Management. Neuroepidemiology 2015;45:34-39.
  • 2. Kesler A, Stolovic N, Bluednikov Y, Shohat T. The incidence of idiopathic intracranial hypertension in Israel from 2005 to 2007: results of a nationwide survey. Eur J Neurol 2014;21:1055-1059.
  • 3. Corbett JJ, Savino PJ, Thompson HS, Kansu T, Schatz NJ, Orr LS, Hopson D. Visual loss in pseudotumor cerebri. Follow-up of 57 patients from five to 41 years and a profile of 14 patients with permanent severe visual loss. Archives of Neurology 1982;39:461-474.
  • 4. Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology 2013;81:1159-1165.
  • 5. Wall M. The headache profile of idiopathic intracranial hypertension. Cephalalgia 1990;10:331-335.
  • 6. Wall M, George D. Idiopathic intracranial hypertension: a prospective study of 50 patients. Brain 1991;114:155-180.
  • 7. Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition (beta version) Cephalalgia 2013;33:629-808.
  • 8. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd ed. Cephalalgia 2004;24(Suppl 1):9-160.
  • 9. Ekizoglu E, Baykan B, Orhan EK, Ertas M. The analysis of allodynia in patients with idiopathic intracranial hypertension. Cephalalgia 2012;32:1049-1058.
  • 10. Bono F, Quattrone A. Idiopathic intracranial hypertension without papilloedema in headache sufferers. Cephalalgia 2009;29:594.
  • 11. Marcelis J, Silberstein SD. Idiopathic intracranial hypertension without papilledema. Arch Neurol 1991;48:392-399.
  • 12. Bruce BB, Kedar S, Van Stavern GP, Monaghan D, Acierno MD, Braswell RA, Preechawat P, Corbett JJ, Newman NJ, Biousse V. Idiopathic intracranial hypertension in men. Neurology 2009;72:304-309.
  • 13. Phillips PH. Pediatric pseudotumor cerebri. Int Ophthalmol Clin 2012;52:51-59.
  • 14. Stiebel-Kalish H, Kalish Y, Lusky M, Gaton DD, Ehrlich R, Shuper A. Puberty as a risk factor for less favorable visual outcome in idiopathic intracranial hypertension. Am J Ophthalmol 2006;142:279-283.
  • 15. Zayit-Soudry S, Leibovitch I, Kesler A. Idiopathic intracranial hypertension after 40 years of age: clinical features in 23 patients. Eur J Ophthalmol 2008;18:989-993.
  • 16. Lee AG, Golnik K, Kardon R, Wall M, Eggenberger E, Yedavally S. Sleep apnea and intracranial hypertension in men. Ophthalmology 2002;109:482- 485.
  • 17. Bruce BB, Preechawat P, Newman NJ, Lynn MJ, Biousse V. Racial differences in idiopathic intracranial hypertension. Neurology 2008;70:861-867.
  • 18. Szewka AJ, Bruce BB, Newman NJ, Biousse V. Idiopathic intracranial hypertension: relation between obesity and visual outcomes. J Neuroophthalmol 2013;33:4-8.
  • 19. Thambisetty M, Lavin PJ, Newman NJ, Biousse V. Fulminant idiopathic intracranial hypertension. Neurology 2007;68:229-232.
  • 20. Biousse V. Idiopathic intracranial hypertension: diagnosis, monitoring and treatment. Rev Neurol (Paris) 2012;168:673-683.
  • 21. Maxner CE, Freedman MI, Corbett JJ. Asymmetric papilledema and visual loss in pseudotumour cerebri. Can J Neurol Sci 1987;14:593-596.
  • 22. Sher NA, Wirtschafter J, Shapiro SK, See C, Shapiro I. Unilateral papilledema in ’benign’ intracranial hypertension (pseudotumor cerebri). JAMA 1983;250:2346-2347.23. Weisberg LA, Housepian EM, Saur DP. Empty sella syndrome as complication of benign intracranial hypertension. J Neurosurg 1975;43:177-180.
  • 24. Sismanis A, Butts FM, Hughes GB. Objective tinnitus in benign intracranial hypertension: an update. Laryngoscope 1990;100:1152-1155.
  • 25. Murphy TP. Otologic manifestations of pseudotumour cerebri. J Otolaryngol 1991;20:258-261.
  • 26. Suryadevara AC, Fattal M, Woods CI. Nontraumatic cerebrospinal fluid rhinorrhea as a result of pseudotumour cerebri. Am J Otolaryngol 2007;28:242-246.
  • 27. Snyder DA, Frenkel M. An unusual presentation of pseudotumour cerebri. Ann Opthalmol 1979;11:1823-1827.
  • 28. Kutz JW, Hussain IA, Isaacson B, Roland PS. Management of spontaneous cerebrospinal fluid otorrhoea. Laryngoscope 2008;118:2195-2199.
  • 29. Giuseffi V, Wall M, Siegel PZ, Rojas PB. Symptoms and disease associations in idiopathic intracranial hypertension (pseudotumor cerebri): a case-control study. Neurology 1991;41:239-244.
  • 30. Wall M, Friedman DI, Corbett JJ. Revised Diagnostic Criteria For The Pseudotumor Cerebri Syndrome In Adults And Children. Neurology 2014;83;198-200.
  • 31. Johnston I, Owler B, Pickard J. The Pseudotumor Cerebri Syndrome: Pseudotumor Cerebri, Idiopathic Intracranial Hypertension, Benign Intracranial Hypertension and Related Conditions. 1st edition, Cambridge University Press; 2007.
  • 32. Skau M, Brennum J, Gjerris F, Jensen R. What is new about idiopathic intracranial hypertension? An updated review of mechanism and treatment. Cephalalgia 2006;26:384-399.
  • 33. Brodsky MC, Vaphiades M. Magnetic resonance imaging in pseudotumor cerebri. Ophthalmology 1998;105:1686-1693.
  • 34. Riggeal BD, Bruce BB, Saindane AM, Ridha MA, Kelly LP, Newman NJ, Biousse V. Clinical course of idiopathic intracranial hypertension with transverse sinus stenosis. Neurology 2013;80:289-295.
  • 35. Salpietro V, Polizzi A, Berte LF, Chimenz R, Chirico V, Manti S, Ferrau V, Salpietro A, Arrigo T, Ruggieri M. Idiopathic intracranial hypertension: a unifying neuroendocrine hypothesis through the adrenal-brain axis. Neuro Endocrinol Lett 2012;33:569-573.
  • 36. Gideon P, Sorensen PS, Thomsen C, Stahlberg F, Gjerris F, Henriksen O. Assessment of CSF dynamics and venous flow in the superior sagittal sinus by MRI in idiopathic intracranial hypertension: a preliminary study. Neuroradiology 1994;36:350-354.
  • 37. King JO, Mitchell PJ, Thomson KR, Tress BM. Manometry combined with cervical puncture in idiopathic intracranial hypertension. Neurology 2002;58:26-30.
  • 38. Strydom MA, Briers N, Bosman MC, Steyn S. The anatomical basis of venographic filling defects of the transverse sinus. Clin Anat 2010;23:153- 159.
  • 39. Bono F, Giliberto C, Mastrandrea C, Cristiano D, Lavano A, Fera F, Quattrone A. Transverse sinus stenoses persist after normalization of the CSF pressure in IIH. Neurology 2005;65:1090-1093.
  • 40. Killer HE, Jaggi GP, Flammer J, Miller NR, Huber A. The optic nerve: a new window into cerebrospinal fluid composition? Brain 2006;129:1027-1030.
  • 41. Killer HE, Jaggi GP, Flammer J, Miller NR, Huber AR, Mironov A. Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve. Is it always bidirectional? Brain 2007;130:514- 520.
  • 42. Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, Jacks A, Lawden M, Clarke CE, Stewart PM, Walker EA, Tomlinson JW, Rauz S. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ 2010;341:c2701.
  • 43. Daniels AB, Liu GT, Volpe NJ, Galetta SL, Moster ML, Newman NJ, Biousse V, Lee AG, Wall M, Kardon R, Acierno MD, Corbett JJ, Maguire MG, Balcer LJ. Profiles of obesity, weight gain, and quality of life in idiopathic intracranial hypertension (pseudotumor cerebri). Am J Ophthalmol 2007;143:635-641.
  • 44. NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee, Wall M, McDermott MP, Kieburtz KD, Corbett JJ, Feldon SE, Friedman DI, Katz DM, Keltner JL, Schron EB, Kupersmith MJ. Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. JAMA 2014;311:1641-1651.
  • 45. Dodgson SJ, Shank RP, Maryanoff BE. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 2000;41(Suppl 1):S35-39.
  • 46. Celebisoy N, Gokcay F, Sirin H, Akyurekli O. Treatment of idiopathic intracranial hypertension: topiramate vs. acetazolamide, an open label study. Acta Neurol Scand 2007;116:322-327.
  • 47. Smith MB, Griffiths EA, Thompson JE, Wang ES, Wetzler M, Freyer CW. High pseudotumor cerebri incidence in tretinoin and arsenic treated acute promyelocytic leukemia and the role of topiramate after acetazolamide failure. Leuk Res Rep 2014;3:62-66.
  • 48. Stanbury RM, Graham EM. Systemic corticosteroid therapy side effects and their management. Br J Ophthalmol 1998;82:704-708.
  • 49. Thenuwara K, Todd MM, Brian JE Jr. Effect of mannitol and furosemide on plasma osmolality and brain water. Anesthesiology 2002;96:416-421.
  • 50. Sinclair AJ, Kuruvath S, Sen D, Nightingale PG, Burdon MA, Flint G. Is cerebrospinal fluid shunting in idiopathic intracranial hypertension worthwhile? A 10-year review. Cephalalgia 2011;31:1627-1633.
  • 51. Lai LT, Danesh-Meyer HV, Kaye AH. Visual outcomes and headache following interventions for idiopathic intracranial hypertension. J Clin Neurosci 2014;21:1670-1678.
  • 52. McGirt MJ, Woodworth G, Thomas G, Miller N, Williams M, Rigamonti D. Cerebrospinal fluid shunt placement for pseudotumor cerebri associated intractable headache: predictors of treatment response and an analysis of long-term outcomes. J Neurosurg 2004;101:627-632.
  • 53. Rosenberg ML, Corbett JJ, Smith C. Cerebrospinal fluid diversion procedures in pseudotumor cerebri. Neurology 1993;43:1071-1072.
  • 54. Burgett RA, Purvin VA, Kawasaki A. Lumboperitoneal shunting for pseudotumor cerebri. Neurology 1997;49:734-739.
  • 55. Eggenberger ER, Miller NR, Vitale S. Lumboperitoneal shunt for the treatment of pseudotumor cerebri. Neurology 1996;46:1524-1530.
  • 56. Chumas PD, Armstrong DC, Drake JM, Kulkarno AV, Hoffman HJ, Humphreys RP, Rutka JT, Hendrick EB. Tonsillar herniation: the rule rather than the exception after lumboperitoneal shunting in the pediatric population. J Neurosurg 1993;78:568-573.
  • 57. Chumas PD, Kulkarni AV, Drake JM, Hoffman HJ, Humphreys RP, Rutka JT. Lumboperitoneal shunting: a retrospective study in the pediatric population. Neurosurgery 1993;32:376-383.
  • 58. McGirt M, Woodworth G, Thomas G, Miller NR, Williams M, Rigamonti D. Frameless stereotactic ventriculoperitoneal shunting for pseudotumor cerebri: an outcomes comparison versus lumboperitoneal shunting. Neurosurgery 2004;55:458-459.
  • 59. Woodworth GF, McGirt MJ, Elfert P, Sciubba DM, Rigamonti D. Frameless stereotactic ventricular shunt placement for idiopathic intracranial hypertension. Stereotact Funct Neurosurg 2005;83:12-16.
  • 60. Abu-Serieh B, Ghassempour K, Duprez T, Raftopoulos C. Stereotactic ventriculoperitoneal shunting for refractory idiopathic intracranial hypertension. Neurosurgery 2007;60:1039-1044.
  • 61. McGirt MJ, Woodworth G, Thomas G, Miller N, Williams M, Rigamonti D: Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intractable headache: predictors of treatment response and an analysis of long-term outcomes. J Neurosurg 2004; 101:627-632.
  • 62. Feldon SE. Visual outcomes comparing surgical techniques for management of severe idiopathic intracranial hypertension. Neurosurg Focus 2007;23:E6.
  • 63. Banta JT, Farris BK. Pseudotumor cerebri and optic nerve sheath decompression. Ophthalmology 2000;107:1907-1912.
  • 64. Bourman ND, Spoor TC, Ramocki JM. Optic nerve sheath decompression for pseudotumor cerebri. Arch Ophthalmol 1988;106:1378-1383.
  • 65. Brodsky MC, Rettele GA. Protracted postsurgical blindness with visual recovery following optic nerve sheath fenestration. Arch Ophthalmol 1997;115:1473-1474.
  • 66. Corbett JJ, Nerad JA, Tse D, Anderson RL. Result of optic nerve sheath fenestration for pseudotumor cerebri. The lateral orbitotomy approach. Arch Ophthalmol 1988;106:1391-1397.
  • 67. Plotnik JL, Kosmorsky GS. Operative complications of optic nerve sheath decompression. Ophthalmology 1993;100:683-690.
  • 68. Smith KH, Wilkinson JT, Brindley GO. Combined third and sixth nerve paresis following optic nerve sheath fenestration. J Clin Neuroophthalmol 1992;12:85- 87.
  • 69. Spoor TC, MacHenry JG. Long term effectiveness of optic nerve sheath decompression for pseudotumor cerebri. Ophthalmology 1993;111:632- 635.
  • 70. Sergott RC, Savino PJ, Bosley TM. Modified optic nerve sheath decompression provides long-term visual improvement for pseudotumor cerebri. Arch Ophthalmol 1998;106:1384-1390.
  • 71. Gupta AK, Rajini Ganth MG, Gupta A. Modified endoscopic optic nerve decompression in idiopathic intracranial hypertension. J Laryngol Otol 2003;117:501-502.
  • 72. Koc K, Anik I, Altintas O, Ceylan S. Endoscopic optic nerve decompression for idiopathic intracranial hypertension in two cases. Case report. Minim Invas Neurosurg 2008;51:72-75.
  • 73. Sencer A, Akcakaya MO, Basaran B, Yorukoglu AG, Aydoseli A, Aras Y, Sencan F, Satana B, Aslan I, Unal OF, Izgi N, Canbolat A. Unilateral endoscopic optic nerve decompression for idiopathic intracranial hypertension: a series of 10 patients. World Neurosurg 2014;82:745-750.
  • 74. Patrocinio JA, Patrocinio LG, Junior FB, da Cunha AR. Endoscopic decompression of the optic nerve in pseudotumor cerebri. Auris Nasus Larynx 2005;32:199-203.
  • 75. Ahmed RM, Wilkinson M, Parker GD, Thurtell MJ, Macdonald J, McCluskey PJ, Allan R, Dunne V, Hanlon M, Owler BK, Halmagyi GM. Transverse sinus stenting for idiopathic intracranial hypertension: a review of 52 patients and of model predictions. AJNR Am J Neuroradiol 2011;32:1408-1414.
  • 76. Kumpe DA, Bennett JL, Seinfeld J, Pelak VS, Chawla A, Tierney M. Dural sinus stent placement for idiopathic intracranial hypertension. J Neurosurg 2012;116:538-548.
  • 77. Karahalios D, Rekate HL, Khayata MH, Apostolides PJ. Elevated intracranial venous pressure as a universal mechanism in pseudotumor cerebri of varying etiologies. Neurology 1996;46:198-202.
  • 78. Rohr A, Dörner L, Stingele R, Buhl R, Alfke K, Jansen O. Reversibility of venous sinus obstruction in idiopathic intracranial hypertension. Am J Neuroradiol 2007;28:656-659.
  • 79. Rohr A, Bindeballe J, Riedel C, van Baalen A, Bartsch T, Doerner L, Jansen O. The entire dural sinus tree is compressed in patients with idiopathic intracranial hypertension: a longitudinal, volumetric magnetic resonance imaging study. Neuroradiology 2012;54:25-33.
APA Akçakaya N, AKÇAKAYA M, Sencer A, YAPICI Z (2017). İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. , 43 - 50.
Chicago Akçakaya Nihan Hande,AKÇAKAYA MEHMET OSMAN,Sencer Altay,YAPICI Zuhal İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. (2017): 43 - 50.
MLA Akçakaya Nihan Hande,AKÇAKAYA MEHMET OSMAN,Sencer Altay,YAPICI Zuhal İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. , 2017, ss.43 - 50.
AMA Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. . 2017; 43 - 50.
Vancouver Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. . 2017; 43 - 50.
IEEE Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z "İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı." , ss.43 - 50, 2017.
ISNAD Akçakaya, Nihan Hande vd. "İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı". (2017), 43-50.
APA Akçakaya N, AKÇAKAYA M, Sencer A, YAPICI Z (2017). İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. Türk Nöroloji Dergisi, 23(2), 43 - 50.
Chicago Akçakaya Nihan Hande,AKÇAKAYA MEHMET OSMAN,Sencer Altay,YAPICI Zuhal İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. Türk Nöroloji Dergisi 23, no.2 (2017): 43 - 50.
MLA Akçakaya Nihan Hande,AKÇAKAYA MEHMET OSMAN,Sencer Altay,YAPICI Zuhal İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. Türk Nöroloji Dergisi, vol.23, no.2, 2017, ss.43 - 50.
AMA Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. Türk Nöroloji Dergisi. 2017; 23(2): 43 - 50.
Vancouver Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı. Türk Nöroloji Dergisi. 2017; 23(2): 43 - 50.
IEEE Akçakaya N,AKÇAKAYA M,Sencer A,YAPICI Z "İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı." Türk Nöroloji Dergisi, 23, ss.43 - 50, 2017.
ISNAD Akçakaya, Nihan Hande vd. "İdiyopatik İntrakraniyal Hipertansiyon: Tanı ve Tedavi Yaklaşımı". Türk Nöroloji Dergisi 23/2 (2017), 43-50.