Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora

Kuş, Çiğdem; TAŞ, Meltem; DURU, Mehmet Emin; Küçükaydın, Selçuk

Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora

Çiğdem KUŞ, (Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry, Muğla/Turkey)

Mehmet Emin DURU, (Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry, Muğla/Turkey)

Meltem TAŞ, (Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry, Muğla/Turkey)

Selçuk KÜÇÜKAYDIN (Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry, Muğla/Turkey)

International Journal of Secondary Metabolite

3 1

Yıl: 2017 Cilt: 4 Sayı: 3 Sayfa Aralığı: 372 - 375 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora

Öz:

Erica species are generally spread along the coasts of Turkey. There are five Erica species in these regions, namely; E. arborea, E. manipuliflora, E, bocquetii, E. sicula subsp. Libanotica and E. spiculifolia salisb. Among these species, E. manipuliflora is commonly found in Muğla and southwest part of Turkey. Erica species are called as "funda", "püren" or "tree heath" locally in Turkey and contain biologically active compounds such as flavonoids, coumarins and triterpenoids. Since ancient times, these species have been used as herbal tea and folk medicine by local people in Turkey. In folk medicine, they are used for diuretic, antiseptic and anti-inflammatory purposes. Inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) is useful for the treatment of Alzheimer's disease. In this study anticholinesterase activity of aqueous extracts of leaves, flowers and aerial parts of E. manipuliflora have been investigated spectrophotometrically. The aerial parts extract of E. manipuliflora among the extracts (70.10%) showed the best inhibitory activity against AChE enzyme at 200 µg/mL concentrations. The extracts of leaves and flowers showed 44.42%, 49.91% inhibitions against acetylcholinesterase enzyme at 200 µg/mL concentrations respectively.The flowers extract of E. manipuliflora (80.41%) exhibited the best BChE inhibitory activity at 200 µg/mL concentrations. At the same concentration, the galantamine showed 82.23% inhibitory activity. Leaves and aerial parts extracts showed 15,75%, 31.62% inhibitory activity against BChE respectively. Hence, aerial parts of E. manipuliflora may be useful as a moderate anticholinesterase agent, and flowers of E. manipuliflora may be useful as the butyrylcholinesterase agent.

Anahtar Kelime:

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Kuş Ç, DURU M, TAŞ M, Küçükaydın S (2017). Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. , 372 - 375.
Chicago	Kuş Çiğdem,DURU Mehmet Emin,TAŞ Meltem,Küçükaydın Selçuk Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. (2017): 372 - 375.
MLA	Kuş Çiğdem,DURU Mehmet Emin,TAŞ Meltem,Küçükaydın Selçuk Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. , 2017, ss.372 - 375.
AMA	Kuş Ç,DURU M,TAŞ M,Küçükaydın S Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. . 2017; 372 - 375.
Vancouver	Kuş Ç,DURU M,TAŞ M,Küçükaydın S Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. . 2017; 372 - 375.
IEEE	Kuş Ç,DURU M,TAŞ M,Küçükaydın S "Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora." , ss.372 - 375, 2017.
ISNAD	Kuş, Çiğdem vd. "Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora". (2017), 372-375.

APA	Kuş Ç, DURU M, TAŞ M, Küçükaydın S (2017). Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. International Journal of Secondary Metabolite, 4(3), 372 - 375.
Chicago	Kuş Çiğdem,DURU Mehmet Emin,TAŞ Meltem,Küçükaydın Selçuk Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. International Journal of Secondary Metabolite 4, no.3 (2017): 372 - 375.
MLA	Kuş Çiğdem,DURU Mehmet Emin,TAŞ Meltem,Küçükaydın Selçuk Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. International Journal of Secondary Metabolite, vol.4, no.3, 2017, ss.372 - 375.
AMA	Kuş Ç,DURU M,TAŞ M,Küçükaydın S Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. International Journal of Secondary Metabolite. 2017; 4(3): 372 - 375.
Vancouver	Kuş Ç,DURU M,TAŞ M,Küçükaydın S Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora. International Journal of Secondary Metabolite. 2017; 4(3): 372 - 375.
IEEE	Kuş Ç,DURU M,TAŞ M,Küçükaydın S "Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora." International Journal of Secondary Metabolite, 4, ss.372 - 375, 2017.
ISNAD	Kuş, Çiğdem vd. "Anticholinesterase activities from aqueous extract of different plant parts of Erica manipuliflora". International Journal of Secondary Metabolite 4/3 (2017), 372-375.