Diagnostic Approach to Breast Lesions by Core Needle Biopsy

YAŞAR ÇELİK, Serkan

Diagnostic Approach to Breast Lesions by Core Needle Biopsy

Serkan YAŞAR ÇELİK (Muğla Sıtkı Koçman University, Faculty of Medicine, Department of Pathology, Muğla, Turkey)

Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi

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Yıl: 2019 Cilt: 33 Sayı: 2 Sayfa Aralığı: 73 - 75 Metin Dili: İngilizce İndeks Tarihi: 24-01-2020

Diagnostic Approach to Breast Lesions by Core Needle Biopsy

Öz:

Objective: Breast cancer is the most frequently diagnosed malignancy and also the leading causeof cancer death in women worldwide. The early diagnosis of the breast carcinoma is very importantin order to decide the optimal treatment. So the usefulness of core needle biopsy in breast lesionsis aimed to be researched in this study.Materials and methods: We analyzed 930 female patients retrospectively from whom core needlebiopsies of the breast lesions were performed by ultrasound-guidance and histopathologicallyevaluated. Age, histopathologic type of the lesions, tumor grade in malignant lesions wereinterpreted.Results: The histopathological diagnosis of 189 (20.32%) patients were malignant tumors, 608(65.38%) were benign lesions such as fibrocystic changes, fibroadenomas, intraductal papillomas,mastitis, fat necrosis and adenosis where 133 (14.30%) were usual breast tissues. Among themalignant tumors 10.58% were diagnosed as special-type-of invasive invasive carcinoma likelobular, tubular, mucinous, medullary and metaplastic carcinomas, while 89.42% of the malignanttumors were classified as Invasive carcinoma of No-Special-Type (NST). Histological grading of theinvasive carcinomas of no-special-type was made according to the Modified-Bloom-Richardsongrading system. The ratio of grade 1,2,3 tumors were 36.09%, 52.66% and 11.25% respectively.Conclusion: Ultrasonography-guided breast-core-needle-biopsy is the most suitable method whichis used preoperatively for quick, accurate diagnosis and the histopathologically correct diagnosticrates are very high with it. Because this method is minimal invasive, it does not damage the breastaesthetically and the lesion histologically. It provides enough tissue for immunohistological studieslike estrogen, progesterone receptors, HER2, MIB-1 to determine the appropriate approach to themalignant tumors and the need for neo-adjuvant theraphy or to decide for the surgical method.

Anahtar Kelime:

Konular: Cerrahi

Meme Lezyonlarına İğne Biyopsisi ile Tanısal Yaklaşım

Öz:

Amaç: Meme kanseri tüm dünyada kadınlarda en sık görülen ve kanserden ölümlerin en başında gelen sebeplerdendir. Meme kanserinin erken tanısı ise en uygun tedavi şemasını saptamak açısından çok önemlidir. Bu nedenle; bu çalışmada, meme lezyonlarında iğne biyopsisinin kullanışlılığının araştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmada meme lezyonlarından ultrasonografi eşliğinde iğne biyopsisi alınan ve histopatolojik değerlendirme yapılan 930 kadın hasta retrospektif olarak incelendi. Yaşları, lezyonlarının histopatolojik tipleri ve malign tümörlerin dereceleri değerlendirildi. Bulgular: Hastalardan 189’unun (%20.32) histopatolojik tanısı malign tümör, 608’inin (%65.38) tanısı fibrokistik değişiklik, fibroadenom, intraduktal papillom, mastit, yağ nekrozu ve adenozis gibi benign lezyonlarken, 133’ü (%14.30) normal meme dokusu olarak tanı almıştı. Malign tümörlerin %10.58’i; Lobüler, tübüler, müsinöz, medüller ve metaplastik karsinomlar gibi özel tip meme karsinomu iken %89.42’si özel tip içermeyen İnvaziv meme karsinomuydu. Özel tip içermeyen İnvaziv meme karsinomlarının histolojik derecelendirmesi Modifiye Bloom Richardson derecelendirme sistemine göre yapıldı. Derece 1,2,3 tümörlerin oranları sırasıyla %36.09, %52.66 ve %11.25 idi. Sonuç: Ultrasonografi eşliğinde yapılan iğne biyopsisi, meme kitlesine cerrahi tedavi öncesi hızlı ve kesin tanı verilebilmesi amacıyla uygulanan en uygun yöntemdir. Çünkü minimal invazivdir, memeye estetik olarak hasar vermez ve lezyonun da histopatolojisini bozmaz. Ayrıca bu yöntem Östrojen, progesteron reseptörleri, HER2 ve MIB-1 gibi immünhistokimyasal çalışmaların ilk başta yapılarak, uygun tedavi yaklaşımını, neo-adjuvan tedavi gereksinimini veya uygun cerrahi metodunu saptamak için yeterli doku sağlar.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YAŞAR ÇELİK S (2019). Diagnostic Approach to Breast Lesions by Core Needle Biopsy. , 73 - 75.
Chicago	YAŞAR ÇELİK Serkan Diagnostic Approach to Breast Lesions by Core Needle Biopsy. (2019): 73 - 75.
MLA	YAŞAR ÇELİK Serkan Diagnostic Approach to Breast Lesions by Core Needle Biopsy. , 2019, ss.73 - 75.
AMA	YAŞAR ÇELİK S Diagnostic Approach to Breast Lesions by Core Needle Biopsy. . 2019; 73 - 75.
Vancouver	YAŞAR ÇELİK S Diagnostic Approach to Breast Lesions by Core Needle Biopsy. . 2019; 73 - 75.
IEEE	YAŞAR ÇELİK S "Diagnostic Approach to Breast Lesions by Core Needle Biopsy." , ss.73 - 75, 2019.
ISNAD	YAŞAR ÇELİK, Serkan. "Diagnostic Approach to Breast Lesions by Core Needle Biopsy". (2019), 73-75.

APA	YAŞAR ÇELİK S (2019). Diagnostic Approach to Breast Lesions by Core Needle Biopsy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, 33(2), 73 - 75.
Chicago	YAŞAR ÇELİK Serkan Diagnostic Approach to Breast Lesions by Core Needle Biopsy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi 33, no.2 (2019): 73 - 75.
MLA	YAŞAR ÇELİK Serkan Diagnostic Approach to Breast Lesions by Core Needle Biopsy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, vol.33, no.2, 2019, ss.73 - 75.
AMA	YAŞAR ÇELİK S Diagnostic Approach to Breast Lesions by Core Needle Biopsy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi. 2019; 33(2): 73 - 75.
Vancouver	YAŞAR ÇELİK S Diagnostic Approach to Breast Lesions by Core Needle Biopsy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi. 2019; 33(2): 73 - 75.
IEEE	YAŞAR ÇELİK S "Diagnostic Approach to Breast Lesions by Core Needle Biopsy." Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, 33, ss.73 - 75, 2019.
ISNAD	YAŞAR ÇELİK, Serkan. "Diagnostic Approach to Breast Lesions by Core Needle Biopsy". Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi 33/2 (2019), 73-75.