Psychiatric Symptoms of Patients with Epilepsy
Yıl: 2019 Cilt: 25 Sayı: 2 Sayfa Aralığı: 94 - 98 Metin Dili: İngilizce DOI: 10.14744/epilepsi.2019.95530 İndeks Tarihi: 04-11-2019
Psychiatric Symptoms of Patients with Epilepsy
Öz: Objectives: Psychiatric symptoms such as anxiety, depressive symptoms, psychotic symptoms, and mental retardation are much more common among patients with epilepsy (PWE) than the general population. This study aimed to evaluate psychiatric symptoms in patients with epilepsy. Methods: Symptom Checklist 90-R Revised (SCL-90-R) was given to all consecutive patients with epilepsy in outpatient Epilepsy Department. Participants completed the SCL-90-R questionnaire. One neurologist and one psychiatrist evaluated these forms. Subscales of somatization, obsessive-compulsive thoughts, interpersonal sensitivity, depression, anxiety, phobic anxiety, psychoticism, paranoid ideation, and hostility were evaluated. Results: A total of 111 PWE and 92 sex- and age- matched control subjects were included. The mean age of the patient group was 34.05±10.90 years. Of the patients, 43 were male and 68 were female. Fourteen (12.61%) patients were diagnosed with mental retardation. Based on our results of mean SCL-90-R score for each item, somatization, obsessive-compulsive symptoms, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism were significantly higher in the patient group than the control subjects. Conclusion: SCL-90-R is an easy test to evaluate psychiatric symptoms. It can be used for PWE to raise awareness of psychiatric symptoms. Once the clinicians become more aware of such symptoms, more accurate approach to the patients will be possible. In terms of follow-up of PWE, not only seizure frequency and severity but also other psychiatric symptoms are important.
Anahtar Kelime: Konular:
Epilepsi Hastalarında Psikiatrik Semptomlar
Öz: Amaç: Epilepsi hastalarında anksiyete, depresif belirtiler, psikotik belirtiler ve mental retardasyon gibi psikiyatrik belirtiler genel populasyona göre daha yaygindir. Bu çalışmanın amacı epilepsi hastalarında psikiyatrik belirtileri değerlendirmektir. Gereç ve Yöntem: Katılımcılara SCL-90-R psikolojik belirti tarama testi uygulandı. Epilepsi polikliniğinde takip edilen epilepsi hastaları ardışık olarak dâhil edildi. Formlar bir psikiyatri ve bir nöroloji uzmanı tarafından değerlendirildi. Somatizasyon, obsesif-kompulsif düşünceler, kişiler arası duyarlılık, depresyon, anksiyete, fobik anksiyete, psikotizm, paranoid düşünce ve düşmanlık alt ölçekleri değerlendirildi. Bulgular: Yüz on bir epilepsi hastası ile cinsiyet ve yaş uyumlu 92 kontrol olgu çalışmaya dâhil edildi. Epilepsi hastalarının yaş ortalaması 34.05±10.90 yıl idi. Hastaların 43’ü erkek, 68’i kadındı. On dört hasta (%12.61) mental retardasyon tanısı aldı. Her madde için ortalama SCL-90-R skoru sonuçlarına dayanarak yapılan değerlendirmede somatizasyon, obsesif kompulsif belirtiler, kişiler arası duyarlılık, depresyon, anksiyete, düşmanlık, fobik anksiyete, paronoid düşünce ve psikotizm semptomları hasta grupta kontrollere göre anlamlı derecede yüksekti. Sonuç: SCL-90-R psikolojik belirti tarama testi psikiyatrik semptomların taranmasında kullanılabilecek kolay bir testtir. Epilepsi hastalarında psikiyatrik semptomlarla ilgili farkındalığı artırmak için kullanılabilir. Klinisyenlerin bu belirtilere farkındalığı arttığında hastalara daha doğru bir yaklaşım mümkün olacaktır. Epilepsi hastalarının izlenmesi açısından sadece nöbet sıklığı ve şiddeti değil aynı zamanda diğer psikiyatrik belirtiler de önemlidir.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Sirven JI. Management of Epilepsy comorbidities. Continuum 2016;22:191–203.
- Marsh L, Rao V. Psychiatric complications in patients with epilepsy: a review. Epilepsy Res 2002;49(1):11–33.
- Kanner AM. Psychiatric issues in epilepsy: the complex relation of mood, anxiety disorders, and epilepsy. Epilepsy Behav 2009;15(1):83–7.
- Mula M. The pharmacological management of psychiatric comorbidities in patients with epilepsy. Pharmacol Res 2016;107:147–53.
- Pohlmann-Eden B, Aldenkamp A, Baker GA, Brandt C, Cendes F, Coras R, et al. The relevance of neuropsychiatric symptoms and cognitive problems in new-onset epilepsy - Current knowledge and understanding. Epilepsy Behav 2015;51:199–209.
- Derogatis LR. SCL-90 Administration, Scoring and Procedures Manual-I for the Revised Version Baltimore, MD: John Hopkins Univ School of Medicine, 1977.
- Dag I. Belirti Tarama Listesi (SCL-90-R)’nin üniversite öğrencileri için güvenilirliği ve geçerliği. Turk Psikiyatri Dergisi 1991;2:5–12.
- Kilic M. Belirti Tarama Listesi (SCL-90-R)’nin Geçerlilik ve Güvenirliği. Turk Psikolojik Danışma ve Rehberlik Dergisi 1991;1(2):45–52.
- Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Allen Hauser W, Mathern G, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010;51(6):1069–77.
- Gaitatzis A, Trimble MR, Sander JW. The psychiatric comorbidity of epilepsy. Acta Neurol Scand 2004;110(4):207–20.
- Kanner AM. Is depression associated with an increased risk of treatment-resistant epilepsy? Research strategies to investigate this question. Epilepsy Behav 2014;38:3–7.
- Gilliam FG, Barry JJ, Hermann BP, Meador KJ, Vahle V, Kanner AM. Rapid detection of major depression in epilepsy: a multicentre study. Lancet Neurol 2006;5(5):399–405.
- Mula M, Iudice A, La Neve A, Mazza M, Bartolini E, De Caro MF, et al. Validation of the Italian version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Epilepsy Behav 2012;24(3):329–31.
- Di Capua D, Garcia-Garcia ME, Reig-Ferrer A, Fuentes-Ferrer M, Toledano R, Gil-Nagel A, et al. Validation of the Spanish ver sion of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Epilepsy Behav 2012;24(4):493–6.
- de Oliveira GN, Kummer A, Salgado JV, Portela EJ, Sousa-Pereira SR, David AS, et al. Brazilian version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Epilepsy Behav 2010;19(3):328–31.
- Zis P, Yfanti P, Siatouni A, Tavernarakis A, Gatzonis S. Validation of the Greek version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Epilepsy Behav 2013;29(3):513–5.
- Rektor I, Schachter SC, Arzy S, Baloyannis SJ, Bazil C, Brázdil M, et al. Epilepsy, behavior, and art (Epilepsy, Brain, and Mind, part 1). Epilepsy Behav 2013;28(2):261–82.
- Barbieri V, Lo Russo G, Francione S, Scarone S, Gambini O. Association of temporal lobe epilepsy and obsessive-compulsive disorder in a patient successfully treated with right temporal lobectomy. Epilepsy Behav 2005;6(4):617–9.
- Kaplan PW. Epilepsy and obsessive-compulsive disorder. Dialogues Clin Neurosci 2010;12(2):241–8.
| APA | Ünal Y, İNANÇ L, SEMİZ Ü, KUTLU G (2019). Psychiatric Symptoms of Patients with Epilepsy. , 94 - 98. 10.14744/epilepsi.2019.95530 |
| Chicago | Ünal Yasemin,İNANÇ LEMAN,SEMİZ Ümit Başar,KUTLU GÜLNİHAL Psychiatric Symptoms of Patients with Epilepsy. (2019): 94 - 98. 10.14744/epilepsi.2019.95530 |
| MLA | Ünal Yasemin,İNANÇ LEMAN,SEMİZ Ümit Başar,KUTLU GÜLNİHAL Psychiatric Symptoms of Patients with Epilepsy. , 2019, ss.94 - 98. 10.14744/epilepsi.2019.95530 |
| AMA | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G Psychiatric Symptoms of Patients with Epilepsy. . 2019; 94 - 98. 10.14744/epilepsi.2019.95530 |
| Vancouver | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G Psychiatric Symptoms of Patients with Epilepsy. . 2019; 94 - 98. 10.14744/epilepsi.2019.95530 |
| IEEE | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G "Psychiatric Symptoms of Patients with Epilepsy." , ss.94 - 98, 2019. 10.14744/epilepsi.2019.95530 |
| ISNAD | Ünal, Yasemin vd. "Psychiatric Symptoms of Patients with Epilepsy". (2019), 94-98. https://doi.org/10.14744/epilepsi.2019.95530 |
| APA | Ünal Y, İNANÇ L, SEMİZ Ü, KUTLU G (2019). Psychiatric Symptoms of Patients with Epilepsy. Epilepsi, 25(2), 94 - 98. 10.14744/epilepsi.2019.95530 |
| Chicago | Ünal Yasemin,İNANÇ LEMAN,SEMİZ Ümit Başar,KUTLU GÜLNİHAL Psychiatric Symptoms of Patients with Epilepsy. Epilepsi 25, no.2 (2019): 94 - 98. 10.14744/epilepsi.2019.95530 |
| MLA | Ünal Yasemin,İNANÇ LEMAN,SEMİZ Ümit Başar,KUTLU GÜLNİHAL Psychiatric Symptoms of Patients with Epilepsy. Epilepsi, vol.25, no.2, 2019, ss.94 - 98. 10.14744/epilepsi.2019.95530 |
| AMA | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G Psychiatric Symptoms of Patients with Epilepsy. Epilepsi. 2019; 25(2): 94 - 98. 10.14744/epilepsi.2019.95530 |
| Vancouver | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G Psychiatric Symptoms of Patients with Epilepsy. Epilepsi. 2019; 25(2): 94 - 98. 10.14744/epilepsi.2019.95530 |
| IEEE | Ünal Y,İNANÇ L,SEMİZ Ü,KUTLU G "Psychiatric Symptoms of Patients with Epilepsy." Epilepsi, 25, ss.94 - 98, 2019. 10.14744/epilepsi.2019.95530 |
| ISNAD | Ünal, Yasemin vd. "Psychiatric Symptoms of Patients with Epilepsy". Epilepsi 25/2 (2019), 94-98. https://doi.org/10.14744/epilepsi.2019.95530 |
