Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?
Yıl: 2018 Cilt: 8 Sayı: 1 Sayfa Aralığı: 20 - 25 Metin Dili: İngilizce DOI: 10.5505/kjms.2018.74317 İndeks Tarihi: 13-02-2020
Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?
Öz: Aim: Pancreatic exocrine dysfunction has many causes and oftenresults in malnutrition. The relationship between chronic renal diseaserelated malnutrition and pancreatic exocrine function has notbeen understood clearly yet. There is lack of data in the literatureregarding pancreas exocrine dysfunction in kidney diseases. Thisstudy aimed to show whether existence of this relationship.Material and Method: 40 End stage renal disease (ESRD) patients,40 chronic renal disease (CKD) patients and 42 healthy volunteerswithout any diagnosed systemic diseases were included.‘Mini Nutritional Assessment’ (MNA) form has been filled up todetermine the nutritional status of the participants. Fecal elastase1 (FE1) levels measured in order to evaluate the exocrine functionof pancreas.Results: FE1 values of control group were significantly higherfrom CKD and ESRD patients both. When considering the sensitivityof FE1 to show pancreas exocrine function, these resultsworsen pancreas exocrine function in patients with kidney disease.Conclusion: Malnutrition in kidney diseases has various reasons,and pancreatic exocrine dysfunction thought to be one of them.FE1 levels may be used in order to evaluate the exocrine functionsof the pancreas.
Anahtar Kelime: Konular:
Kronik Böbrek Hastalığı ve Son Dönem Böbrek Hastalığı’nda Malnütrisyon Pankreatik Ekzokrin Disfonksiyon ile İlişkili Olabilir mi?
Öz: Amaç: Kronik böbrek hastalığı (KBH) ilişkili malnutrisyon ile pankreatik ekzokrin disfonksiyon arasındaki ilişki henüz net olarak açıklanamamıştır. Böbrek hastalıklarında pankreatik ekzokrin Introduction End stage renal disease (ESRD) and chronic renal disease (CRD) are serious health care problems with increasing incidences, and 5 year-mortality rates are about 60% which is due to the disease itself and the complications. Malnutrition is supposed to be one of the leading causes that contributing reasons. Malnutrition prevalence is predicted as 10–70%, and 18–50% receiving hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) therapies respectively1–4. disfonksiyona ilişkin literatür yeterli değildir. Bu çalışmanın amacı böyle bir ilişkinin olup olmadığının araştırılmasıdır. Materyal ve Metot: 40 SDBH, 40 KBH ve 42 sağlıklı gönüllünün dahil edildiği çalışmada katılımcıların beslenme durumlarının belirlenmesi amacıyla “Kısa Nütrisyonel Değerlendirme (KND)” formu doldurulmuş ve pankreasın ekzokrin işlevlerinin belirlenmesi için fekal elastaz 1 (FE1) düzeyleri ölçülmüştür. Bulgular: Kontrol grubunda FE1 düzeyleri KBH ve SDBH ggruplarına göre anlamlı derecede yüksek bulunmuştur. FE1’in pankreas ekzokrin fonksiyonunu göstermedeki duyarlılığı göz önüne alındığında, sonuçlar böbrek hastalarında kötü pankreatik ekzokrin fonksiyonunu işaret etmektedir. Sonuç: Böbrek hastalığında malnutrisyonun çok farklı nedenleri olabilmesinin yanı sıra, pankreatik ekzokrin disfonksiyon bu nedenlerden biri olarak düşünülebilir. FE1 düzeyleri pankreasın ekzokrin fonksiyonunun belirlenmesinde kullanılabilir.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Huddam B, AZAK A, DEMİRHAN Ö, BAYRAKTAR N, karakuş v, DERE Y, Sezer S (2018). Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. , 20 - 25. 10.5505/kjms.2018.74317 |
| Chicago | Huddam Bülent,AZAK Alper,DEMİRHAN Özgür,BAYRAKTAR NILÜFER,karakuş volkan,DERE YELDA,Sezer Siren Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. (2018): 20 - 25. 10.5505/kjms.2018.74317 |
| MLA | Huddam Bülent,AZAK Alper,DEMİRHAN Özgür,BAYRAKTAR NILÜFER,karakuş volkan,DERE YELDA,Sezer Siren Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. , 2018, ss.20 - 25. 10.5505/kjms.2018.74317 |
| AMA | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. . 2018; 20 - 25. 10.5505/kjms.2018.74317 |
| Vancouver | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. . 2018; 20 - 25. 10.5505/kjms.2018.74317 |
| IEEE | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S "Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?." , ss.20 - 25, 2018. 10.5505/kjms.2018.74317 |
| ISNAD | Huddam, Bülent vd. "Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?". (2018), 20-25. https://doi.org/10.5505/kjms.2018.74317 |
| APA | Huddam B, AZAK A, DEMİRHAN Ö, BAYRAKTAR N, karakuş v, DERE Y, Sezer S (2018). Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. Kafkas Tıp Bilimleri Dergisi, 8(1), 20 - 25. 10.5505/kjms.2018.74317 |
| Chicago | Huddam Bülent,AZAK Alper,DEMİRHAN Özgür,BAYRAKTAR NILÜFER,karakuş volkan,DERE YELDA,Sezer Siren Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. Kafkas Tıp Bilimleri Dergisi 8, no.1 (2018): 20 - 25. 10.5505/kjms.2018.74317 |
| MLA | Huddam Bülent,AZAK Alper,DEMİRHAN Özgür,BAYRAKTAR NILÜFER,karakuş volkan,DERE YELDA,Sezer Siren Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. Kafkas Tıp Bilimleri Dergisi, vol.8, no.1, 2018, ss.20 - 25. 10.5505/kjms.2018.74317 |
| AMA | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. Kafkas Tıp Bilimleri Dergisi. 2018; 8(1): 20 - 25. 10.5505/kjms.2018.74317 |
| Vancouver | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?. Kafkas Tıp Bilimleri Dergisi. 2018; 8(1): 20 - 25. 10.5505/kjms.2018.74317 |
| IEEE | Huddam B,AZAK A,DEMİRHAN Ö,BAYRAKTAR N,karakuş v,DERE Y,Sezer S "Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?." Kafkas Tıp Bilimleri Dergisi, 8, ss.20 - 25, 2018. 10.5505/kjms.2018.74317 |
| ISNAD | Huddam, Bülent vd. "Is There Any Contribution of Pancreatic Exocrine Dysfunction to the Malnutrition in Chronic Kidney Disease and End Stage Renal Disease?". Kafkas Tıp Bilimleri Dergisi 8/1 (2018), 20-25. https://doi.org/10.5505/kjms.2018.74317 |
