Yıl: 2020 Cilt: 27 Sayı: 1 Sayfa Aralığı: 292 - 296 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.09.584 İndeks Tarihi: 13-10-2020

Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery

Öz:
Aim: The association between modified Glasgow prognostic score (mGPS) and prognosis in patients undergoing hip fracture surgery(HFS) has not been studied. Therefore, we aimed to evaluate the predictive value of mGPS in outcomes of patients undergoing HFS..Material and Methods: A total of 301 adult patients aged ≥ 65 years, undergoing HFS were included in this retrospective study. ThemGPS was scored according to C-reactive protein (CRP) and albumin levels at enrolment. Patients with both elevated CRP (>1 mg/dL)and hypoalbuminemia (<3.5 g/dL) are given mGPS of 2, patients with serum CRP ≤ 1 g/dL with or without hypoalbuminemia receivedscores of 0. Patients with only elevated CRP levels received mGPS of 1. Primary outcome of the study was major perioperativeadverse medical events defined as cardiovascular and noncardiovascular complications.Results: A total of 38 patients (12.6%) experienced perioperative adverse medical events. Compared to patients without perioperativecomplications, patients with adverse events were more likely to have higher mGPS levels prior to surgert. Multivariate analysis showedthat higher mGPS at presentation was an independent predictor of perioperative adverse medical events in patients undergoing HFS.Conclusion: This is the first study which demonstrates that mGPS is a predictor of adverse events in patients with undergoing HFS.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Chen FP, Shyu YC, Fu TS, et al. Secular trends in incidence and recurrence rates of hip fracture: a nationwide population-based study. Osteoporos Int 2017;28:811-8.
  • 2. Flikweert ER, Wendt KW, Diercks RL, et al. Complications after hip fracture surgery: are they preventable? Eur J Trauma Emerg Surg 2018;44:573-80.
  • 3. Carpintero P, Caeiro JR, Carpintero R, Morales A, Silva S, Mesa M. Complications of hip fractures: A review. World J Orthop 2014;5:402-11.
  • 4. Mak JC, Cameron ID, March LM. National Health and Medical Research Council. Evidence-based guidelines for the management of hip fractures in older persons: an update. Med J Aust 2010;192:37-41.
  • 5. Bell JJ, Pulle RC, Crouch AM, et al. Impact of malnutrition on 12-month mortality following acute hip fracture. ANZ J Surg 2016;86:157-61.
  • 6. Yoo JI, Ha YC, Choi H, et al. Malnutrition and chronic inflammation as risk factors for sarcopenia in elderly patients with hip fracture. Asia Pac J Clin Nutr 2018;27:527-32.
  • 7. van Wissen J, van Stijn MF, Doodeman HJ, et al. Mini Nutritional Assessment and Mortality after Hip Fracture Surgery in the Elderly. J Nutr Health Aging 2016;20:964-8.
  • 8. Aldebeyan S, Nooh A, Aoude A, et al. Hypoalbuminaemia-a marker of malnutrition and predictor of postoperative complications and mortality after hip fractures. Injury 2017;48:436-40.
  • 9. Levitt DG, Levitt MD. Human serum albumin homeostasis: a new look at the roles of synthesis, catabolism, renal and gastrointestinal excretion, and the clinical value of serum albumin measurements. Int J Gen Med. 2016;9:229-55.
  • 10. Petrelli F, Barni S, Coinu A, et al. The Modified Glasgow Prognostic Score and Survival in Colorectal Cancer: A Pooled Analysis of the Literature. Rev Recent Clin Trials 2015;10:135-41.
  • 11. McMillan DC. The systemic inflammation-based Glasgow Prognostic Score: a decade of experience in patients with cancer. Cancer Treat Rev 2013;39:534- 40.
  • 12. Kang HS, Cho KW, Kwon SS, et al. Prognostic significance of Glasgow prognostic score in patients with acute exacerbation of idiopathic pulmonary fibrosis. Respirology 2018;23:206-12.
  • 13. Delcea C, Dima A, Jurcut C, et al. Utility of the Glasgow Prognostic Score in systemic lupus erythematosus, in a Single Center Cohort of 130 Patients. Ann Rheum Dis 2015;74:638.
  • 14. Zhao C, Ding C, Xie T, et al. Validation and optimization of the Systemic Inflammation-Based modified Glasgow Prognostic Score in predicting postoperative outcome of inflammatory bowel disease: preliminary data. Sci Rep 2018;8:747.
  • 15. Cenzer IS, Tang V, Boscardin WJ,et al. One-Year Mortality After Hip Fracture: Development and Validation of a Prognostic Index. J Am Geriatr Soc 2016;64:1863-8.
  • 16. Katsanos S, Mavrogenis AF, Kafkas N, et al. Cardiac Biomarkers Predict 1-Year Mortality in Elderly Patients Undergoing Hip Fracture Surgery. Orthopedics. 2017;40:417-24.
  • 17. Helminen H, Luukkaala T, Saarnio J, et al. Comparison of the Mini-Nutritional Assessment short and long form and serum albumin as prognostic indicators of hip fracture outcomes. Injury 2017;48:903-8.
  • 18. Shoji F. Clinical impact of preoperative immunonutritional status in patients undergoing surgical resection of lung cancer. J Thorac Dis 2019;11:408-12.
  • 19. Nakao M, Muramatsu H, Arakawa S, et al. Immunonutritional status and pulmonary cavitation in patients with tuberculosis: A revisit with an assessment of neutrophil/lymhocyte ratio. Respir Investig 2019;57:60-6.
  • 20. Malafarina V, Reginster JY, Cabrerizo S, et al. Nutritional Status and Nutritional Treatment Are Related to Outcomes and Mortality in Older Adults with Hip Fracture. Nutrients 2018;10:555.
  • 21. Southwell-Keely JP, Russo RR, March L, et al. Antibiotic prophylaxis in hip fracture surgery: a metaanalysis. Clin Orthop Relat Res 2004;419:179-84.
  • 22. Hanru Ren, Lianghao Wu, Wankun Hu, et al. Prognostic value of the c-reactive protein/prognostic nutritional index ratio after hip fracture surgery in the elderly population. Oncotarget 2017;8:61365-72.
  • 23. Lv Y, Pan Y, Dong C, et al. Modified Glasgow Prognostic Score at Recurrence Predicts Poor Survival in Resected Non-Small Cell Lung Cancer (NSCLC) Patients. Med Sci Monit 2017;23:3780-8.
  • 24. Zhang X, Chen X, Wu T, et al. Modified Glasgow prognostic score as a prognostic factor in gastric cancer patients: a systematic review and metaanalysis. Int J Clin Exp Med 2015;8:15222-9.
APA Açan A, kilinc c (2020). Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. , 292 - 296. 10.5455/annalsmedres.2019.09.584
Chicago Açan Ahmet Emrah,kilinc cem yalin Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. (2020): 292 - 296. 10.5455/annalsmedres.2019.09.584
MLA Açan Ahmet Emrah,kilinc cem yalin Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. , 2020, ss.292 - 296. 10.5455/annalsmedres.2019.09.584
AMA Açan A,kilinc c Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. . 2020; 292 - 296. 10.5455/annalsmedres.2019.09.584
Vancouver Açan A,kilinc c Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. . 2020; 292 - 296. 10.5455/annalsmedres.2019.09.584
IEEE Açan A,kilinc c "Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery." , ss.292 - 296, 2020. 10.5455/annalsmedres.2019.09.584
ISNAD Açan, Ahmet Emrah - kilinc, cem yalin. "Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery". (2020), 292-296. https://doi.org/10.5455/annalsmedres.2019.09.584
APA Açan A, kilinc c (2020). Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. Annals of Medical Research, 27(1), 292 - 296. 10.5455/annalsmedres.2019.09.584
Chicago Açan Ahmet Emrah,kilinc cem yalin Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. Annals of Medical Research 27, no.1 (2020): 292 - 296. 10.5455/annalsmedres.2019.09.584
MLA Açan Ahmet Emrah,kilinc cem yalin Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. Annals of Medical Research, vol.27, no.1, 2020, ss.292 - 296. 10.5455/annalsmedres.2019.09.584
AMA Açan A,kilinc c Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. Annals of Medical Research. 2020; 27(1): 292 - 296. 10.5455/annalsmedres.2019.09.584
Vancouver Açan A,kilinc c Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery. Annals of Medical Research. 2020; 27(1): 292 - 296. 10.5455/annalsmedres.2019.09.584
IEEE Açan A,kilinc c "Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery." Annals of Medical Research, 27, ss.292 - 296, 2020. 10.5455/annalsmedres.2019.09.584
ISNAD Açan, Ahmet Emrah - kilinc, cem yalin. "Modified Glasgow prognostic score predicts perioperative adverse events in elderly patients undergoing hip fracture surgery". Annals of Medical Research 27/1 (2020), 292-296. https://doi.org/10.5455/annalsmedres.2019.09.584