Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study

signifiObjective:The aim of this study was to describe the current status of aspirin use and the demographic characteristics of patients on aspirin for primary and secondary prevention of cardiovascular diseases.Methods: The Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) trial was a multicenter, cross-sectional, and observational study conducted in Turkey. The study was planned to include 5000 patients from 14 cities in Turkey. The data were collected at one visit, and the current clinical practice regarding aspirin use was evaluated (ClinicalTrials.gov number NCT03387384).Results: The study enrolled all consecutive patients who were admitted to the outpatient cardiology clinics from March 2018 until June 2018. Patients should be at least 18 years old, have signed written informed consent, and on aspirin (80–325 mg) therapy within the last 30 days. Cardiologists from the hospital participates in the study. Patients were divided into 2 categories according to presence or absence of atherosclerotic cardiovascular disease, namely secondary prevention group and primary prevention group, respectively. The appropriate use of aspirin in the primary and secondary prevention groups was assessed according to the European Society of Cardiology guidelines and US Preventive Services Task Force. The patients’ gastrointestinal bleeding risk factors and colorectal cancer risk were evaluated.Conclusion: The ASSOS registry will be the most comprehensive and largest study in Turkey evaluating the appropriateness of aspirin use. The results of this study help understand the potential misuse of aspirin in a real-world setting. (Anatol J Cardiol 2018; 20: 354-62)

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APA	ÇELİK O, ÇİL C, ÖZLEK B, ÖZLEK E, doğan v, basaran o, Demirci E, BEKAR L, KALÇIK M, KARAARSLAN O, Yetim M, Doğan T, DEMİR V, Kalkan S, ÖZKAN B, HİDAYET Ş, TAYLAN G, Kucuksu Z, ÇELİK M, EFE S, Aslan O, BİTEKER M (2018). Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. , 354 - 362. 10.14744/AnatolJCardiol.2018.47587
Chicago	ÇELİK OĞUZHAN,ÇİL CEM,ÖZLEK BÜLENT,ÖZLEK EDA,doğan volkan,basaran ozcan,Demirci Erkan,BEKAR Lütfü,KALÇIK Macit,KARAARSLAN OSMAN,Yetim Mucahit,Doğan Tolga,DEMİR Vahit,Kalkan Sedat,ÖZKAN Buğra,HİDAYET Şıho,TAYLAN Gökay,Kucuksu Zafer,ÇELİK M. Yunus,EFE Süleyman ÇAĞAN,Aslan Onur,BİTEKER MURAT Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. (2018): 354 - 362. 10.14744/AnatolJCardiol.2018.47587
MLA	ÇELİK OĞUZHAN,ÇİL CEM,ÖZLEK BÜLENT,ÖZLEK EDA,doğan volkan,basaran ozcan,Demirci Erkan,BEKAR Lütfü,KALÇIK Macit,KARAARSLAN OSMAN,Yetim Mucahit,Doğan Tolga,DEMİR Vahit,Kalkan Sedat,ÖZKAN Buğra,HİDAYET Şıho,TAYLAN Gökay,Kucuksu Zafer,ÇELİK M. Yunus,EFE Süleyman ÇAĞAN,Aslan Onur,BİTEKER MURAT Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. , 2018, ss.354 - 362. 10.14744/AnatolJCardiol.2018.47587
AMA	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. . 2018; 354 - 362. 10.14744/AnatolJCardiol.2018.47587
Vancouver	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. . 2018; 354 - 362. 10.14744/AnatolJCardiol.2018.47587
IEEE	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M "Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study." , ss.354 - 362, 2018. 10.14744/AnatolJCardiol.2018.47587
ISNAD	ÇELİK, OĞUZHAN vd. "Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study". (2018), 354-362. https://doi.org/10.14744/AnatolJCardiol.2018.47587

APA	ÇELİK O, ÇİL C, ÖZLEK B, ÖZLEK E, doğan v, basaran o, Demirci E, BEKAR L, KALÇIK M, KARAARSLAN O, Yetim M, Doğan T, DEMİR V, Kalkan S, ÖZKAN B, HİDAYET Ş, TAYLAN G, Kucuksu Z, ÇELİK M, EFE S, Aslan O, BİTEKER M (2018). Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. The Anatolian Journal of Cardiology, 20(6), 354 - 362. 10.14744/AnatolJCardiol.2018.47587
Chicago	ÇELİK OĞUZHAN,ÇİL CEM,ÖZLEK BÜLENT,ÖZLEK EDA,doğan volkan,basaran ozcan,Demirci Erkan,BEKAR Lütfü,KALÇIK Macit,KARAARSLAN OSMAN,Yetim Mucahit,Doğan Tolga,DEMİR Vahit,Kalkan Sedat,ÖZKAN Buğra,HİDAYET Şıho,TAYLAN Gökay,Kucuksu Zafer,ÇELİK M. Yunus,EFE Süleyman ÇAĞAN,Aslan Onur,BİTEKER MURAT Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. The Anatolian Journal of Cardiology 20, no.6 (2018): 354 - 362. 10.14744/AnatolJCardiol.2018.47587
MLA	ÇELİK OĞUZHAN,ÇİL CEM,ÖZLEK BÜLENT,ÖZLEK EDA,doğan volkan,basaran ozcan,Demirci Erkan,BEKAR Lütfü,KALÇIK Macit,KARAARSLAN OSMAN,Yetim Mucahit,Doğan Tolga,DEMİR Vahit,Kalkan Sedat,ÖZKAN Buğra,HİDAYET Şıho,TAYLAN Gökay,Kucuksu Zafer,ÇELİK M. Yunus,EFE Süleyman ÇAĞAN,Aslan Onur,BİTEKER MURAT Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. The Anatolian Journal of Cardiology, vol.20, no.6, 2018, ss.354 - 362. 10.14744/AnatolJCardiol.2018.47587
AMA	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. The Anatolian Journal of Cardiology. 2018; 20(6): 354 - 362. 10.14744/AnatolJCardiol.2018.47587
Vancouver	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study. The Anatolian Journal of Cardiology. 2018; 20(6): 354 - 362. 10.14744/AnatolJCardiol.2018.47587
IEEE	ÇELİK O,ÇİL C,ÖZLEK B,ÖZLEK E,doğan v,basaran o,Demirci E,BEKAR L,KALÇIK M,KARAARSLAN O,Yetim M,Doğan T,DEMİR V,Kalkan S,ÖZKAN B,HİDAYET Ş,TAYLAN G,Kucuksu Z,ÇELİK M,EFE S,Aslan O,BİTEKER M "Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study." The Anatolian Journal of Cardiology, 20, ss.354 - 362, 2018. 10.14744/AnatolJCardiol.2018.47587
ISNAD	ÇELİK, OĞUZHAN vd. "Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study". The Anatolian Journal of Cardiology 20/6 (2018), 354-362. https://doi.org/10.14744/AnatolJCardiol.2018.47587