Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer
Yıl: 2018 Cilt: 29 Sayı: 4 Sayfa Aralığı: 280 - 284 Metin Dili: İngilizce DOI: 10.14744/scie.2018.63625 İndeks Tarihi: 29-11-2020
Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer
Öz: Objective: Malnutrition in geriatric patients with colorectal cancer (CRC), especially thosewho received chemotherapy (CT), is a frequent condition. The aim of this study was to determine the effect of CT on malnutrition in patients with geriatric metastatic CRC (mCRC).Methods: A total of 136 patients aged 70 years and older, and diagnosed with mCRC, wereenrolled in the study. The nutritional status of the patients was evaluated with the Nutritional Risk Score-2002 before CT and after one CT course.Results: The median follow-up time was 18.5 months. The median age was 74. The ECOGperformance score of all patients was 0 or 1. 62.5% had liver metastasis, 26% had lung metastasis, 25% peritoneal metastasis, and 8% bone metastasis. It was determined that 17.3% ofpatients were malnurished, and 24.6% had a risk of malnutrition. 49.4% of patients with preCT weight loss have begun. The average weight loss before the first CT was 12.1%, and theincidence of malnutrition after one course of CT was 46.4% (p=0.001).Conclusion: Malnutrition is frequently observed in patients with geriatric mCRC, and evena single course of CT increases malnutrition in patients.
Anahtar Kelime: Metastatik Kolorektal Kanser Tanılı Geriatrik Grupta Kemoterapinin Malnütrisyon Üzerine Etkisi
Öz: Amaç: Geriatrik kolorektal (KRK) kanser hastalarında, özellikle kemoterapi (KT) sonrası malnütrisyon sık gözlenen bir durumdur. Bu çalışmanın amacı KT’nin geriatrik metastatik KRK kanseri (mKRK) hastalarında malnütrisyon durumu üzerine etkisini belirlemektir. Gereç ve Yöntem: Kemoterapi alan 70 yaş ve üzeri 136 mKRK tanılı hasta çalışmaya alınmıştır. Hastaların beslenme durumu Nutritional risk score-2002 (NRS-2002) ile KT öncesi ve KT’den bir kür sonra değerlendirilmiştir. Bulgular: Çalışmaya 70 yaş ve üzeri, ilk seri KT başlanacak 136 mKRK hastası alınmıştır. Median takip süresi 18.5 aydır. Ortalama yaş 74’dür. Tüm hastaların ECOG performance skoru 0 veya 1’dir. %62.5’inde karaciğer metastazı, %26’sında akciğer metastazı, %25’inde periton metastazı, %8’inde kemik metastazı mevcuttur. Hastaların %27.9’unun malnütrisyonu olduğu, %24.6’sının da malnütrisyon riski bulunduğu belirlenmiştir. %33.6 hastada ilk vizit öncesi kilo kaybı yoktur, %66.4 hastada KT öncesi kilo kaybı başlamıştır. İlk vizit öncesi ortalama kilo kaybı %12.1’dir Bir kür KT sonrası malnütrisyon sıklığı %46.4’e çıkmıştır (p=0.001). Sonuç: Malnütrisyon geriatrik mKRK bulunan hastalarda sık gözlenmekte olup, tek bir kür KT bile hastaların malnütrisyonunu artırmıştır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | NAMAL E (2018). Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. , 280 - 284. 10.14744/scie.2018.63625 |
| Chicago | NAMAL Esat Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. (2018): 280 - 284. 10.14744/scie.2018.63625 |
| MLA | NAMAL Esat Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. , 2018, ss.280 - 284. 10.14744/scie.2018.63625 |
| AMA | NAMAL E Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. . 2018; 280 - 284. 10.14744/scie.2018.63625 |
| Vancouver | NAMAL E Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. . 2018; 280 - 284. 10.14744/scie.2018.63625 |
| IEEE | NAMAL E "Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer." , ss.280 - 284, 2018. 10.14744/scie.2018.63625 |
| ISNAD | NAMAL, Esat. "Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer". (2018), 280-284. https://doi.org/10.14744/scie.2018.63625 |
| APA | NAMAL E (2018). Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. Southern Clinics of Istanbul Eurasia, 29(4), 280 - 284. 10.14744/scie.2018.63625 |
| Chicago | NAMAL Esat Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. Southern Clinics of Istanbul Eurasia 29, no.4 (2018): 280 - 284. 10.14744/scie.2018.63625 |
| MLA | NAMAL Esat Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. Southern Clinics of Istanbul Eurasia, vol.29, no.4, 2018, ss.280 - 284. 10.14744/scie.2018.63625 |
| AMA | NAMAL E Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. Southern Clinics of Istanbul Eurasia. 2018; 29(4): 280 - 284. 10.14744/scie.2018.63625 |
| Vancouver | NAMAL E Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer. Southern Clinics of Istanbul Eurasia. 2018; 29(4): 280 - 284. 10.14744/scie.2018.63625 |
| IEEE | NAMAL E "Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer." Southern Clinics of Istanbul Eurasia, 29, ss.280 - 284, 2018. 10.14744/scie.2018.63625 |
| ISNAD | NAMAL, Esat. "Effect of Chemotherapy on Malnutrition in Geriatric Group With Metastatic Colorectal Cancer". Southern Clinics of Istanbul Eurasia 29/4 (2018), 280-284. https://doi.org/10.14744/scie.2018.63625 |
