The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat

DEMİRYONT, Misten; ÖZDEN, Çelet Burcu; TÜMERDEM, Burçak; EMEKLİ, Ufuk; KEMİKLER, Gönül; AKTAŞ, ŞAMİL

The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat

Burçak TÜMERDEM, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı, İstanbul, Türkiye)

Ufuk EMEKLİ, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı, İstanbul, Türkiye)

Çelet Burcu ÖZDEN, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı, İstanbul, Türkiye)

Şamil AKTAŞ, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Sualtı Hekimliği ve Hiperbarik Tıp Anabilim Dalı, İstanbul, Türkiye)

Misten DEMİRYONT, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Patoloji Anabilim Dalı, İstanbul, Türkiye)

Gönül KEMİKLER (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Turkish Journal of Medical Sciences

1 0

Yıl: 2004 Cilt: 34 Sayı: 1 Sayfa Aralığı: 29 - 35 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat

Öz:

Under conditions that may risk the success of flap surgery, free skin grafting may be an option for the reconstruction of the irradiated area. Clinical observations reveal that skin grafts applied to irradiated area undergo ulceration, resulting in chronic open wounds. The role of hyperbaric oxygen therapy (HBO) in problem wounds is to increase the tissue oxygen tension to optimize fibroblast proliferation and collagen synthesis, to enhance the oxidative killing capacity of the white blood cells and to stimulate angiogenesis. HBO has also been shown to stimulate angiogenesis in radiation-damaged tissue. In view of this data, an animal model is designed to investigate the effect of HBO therapy on the survival of a skin graft applied on a previously irradiated area. HBO therapy was started on the day of surgery and was continued for 20 days. Graft survival in each rat was calculated as a percentage of the total graft. There was no statistically significant difference between the mean value of the graft survival rate of HBO-treated and HBO-untreated groups.

Anahtar Kelime: Hyperbaric Oxygenation Rats, Wistar Radiotherapy Radiation Transplants

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TÜMERDEM B, EMEKLİ U, ÖZDEN Ç, AKTAŞ Ş, DEMİRYONT M, KEMİKLER G (2004). The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. , 29 - 35.
Chicago	TÜMERDEM Burçak,EMEKLİ Ufuk,ÖZDEN Çelet Burcu,AKTAŞ ŞAMİL,DEMİRYONT Misten,KEMİKLER Gönül The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. (2004): 29 - 35.
MLA	TÜMERDEM Burçak,EMEKLİ Ufuk,ÖZDEN Çelet Burcu,AKTAŞ ŞAMİL,DEMİRYONT Misten,KEMİKLER Gönül The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. , 2004, ss.29 - 35.
AMA	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. . 2004; 29 - 35.
Vancouver	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. . 2004; 29 - 35.
IEEE	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G "The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat." , ss.29 - 35, 2004.
ISNAD	TÜMERDEM, Burçak vd. "The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat". (2004), 29-35.

APA	TÜMERDEM B, EMEKLİ U, ÖZDEN Ç, AKTAŞ Ş, DEMİRYONT M, KEMİKLER G (2004). The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. Turkish Journal of Medical Sciences, 34(1), 29 - 35.
Chicago	TÜMERDEM Burçak,EMEKLİ Ufuk,ÖZDEN Çelet Burcu,AKTAŞ ŞAMİL,DEMİRYONT Misten,KEMİKLER Gönül The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. Turkish Journal of Medical Sciences 34, no.1 (2004): 29 - 35.
MLA	TÜMERDEM Burçak,EMEKLİ Ufuk,ÖZDEN Çelet Burcu,AKTAŞ ŞAMİL,DEMİRYONT Misten,KEMİKLER Gönül The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. Turkish Journal of Medical Sciences, vol.34, no.1, 2004, ss.29 - 35.
AMA	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. Turkish Journal of Medical Sciences. 2004; 34(1): 29 - 35.
Vancouver	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat. Turkish Journal of Medical Sciences. 2004; 34(1): 29 - 35.
IEEE	TÜMERDEM B,EMEKLİ U,ÖZDEN Ç,AKTAŞ Ş,DEMİRYONT M,KEMİKLER G "The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat." Turkish Journal of Medical Sciences, 34, ss.29 - 35, 2004.
ISNAD	TÜMERDEM, Burçak vd. "The effect of hyperbaric oxygen therapy (HBO) when used postoperatively in skin grafting over radiated tissue in the rat". Turkish Journal of Medical Sciences 34/1 (2004), 29-35.