Yakup ENSARİ, Yelda Tarkan ARGÜDEN
Yakup ENSARİ, Yelda Tarkan ARGÜDEN
Bilimin başlangıcı ve şekillenme sürecini açıklamak, klasik bilimden modern bilime geçiş sürecini ve bu değişimin nedenlerini aktarmak,Aristo ve Galenos’ un çalışmalarının tıp ve birçok farklı alanda dünyada uzun süre etki gösterdiğini belirtmek ve bunun sebeplerini ortayakoymak, bilim serüveninde önemli gelişmeler kaydeden şahsiyetleri ve bulgularının bilimin gelişimine katkılarını göstermek, geçmiştengünümüze objektif bir analiz ile bilime dair farklı bakış açıları ve sorgulama alanları oluşturmak bu yazının amaçlarıdır. İnsan hayatınıkolaylaştıran, dünya düzenini değiştiren, toplumsal ve bireysel gelişime ve teknolojiye kaynaklık eden bilimin modern ve sistematikkonumuna ulaşması ve tüm bu dinamik süreçteki parametreler irdelenerek genel bir açıklama ve sorgulayıcı bir metin oluşturularakokuyucuya sunulmuştur.
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Melis Akpınar GÖZETİCİ, Avidan KIZILELMA YİĞİT, Ömer Faruk BEŞER
Melis Akpınar GÖZETİCİ, Avidan KIZILELMA YİĞİT, Ömer Faruk BEŞER
Objective: This study aimed to investigate the effect of phototherapy on serum electrolyte levels in neonates admitted to neonatal intensive care unit with the diagnosis of neonatal hyperbilirubinemia.Methods: Demographic profiles, laboratory findings, and electrolyte levels before phototherapy and 48-72 hours after phototherapy of260 patients hospitalized with neonatal hyperbilirubinemia between June 2016 and June 2018 were compared in this retrospective study.Results: The mean sodium level significantly decreased from 140.5 mg/dL to 139.1 mg/dL after phototherapy. The decrease in potassiumlevel was not statistically significant. The mean calcium level significantly decreased from 9.98 mg/dL to 9.55 mg/dL. The mean chloridelevel before phototherapy significantly decreased from 106.4 mmol/L to 105.9 mmol/L after phototherapy.Conclusion: The level of serum electrolytes in newborns may change with phototherapy. Serum sodium, chloride, and calcium levelsmay decrease after phototherapy. For prevention of possible adverse effects, the changes in electrolyte levels should be considered in theclinical course of newborns receiving phototherapy and appropriate fluid-electrolyte treatments should be given.
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Altan ALİM, Mehmet ELİÇEVİK, Elmas Reyhan ALİM, Zerrin ÖNAL, Günay CAN, Osman Faruk ŞENYÜZ
Altan ALİM, Mehmet ELİÇEVİK, Elmas Reyhan ALİM, Zerrin ÖNAL, Günay CAN, Osman Faruk ŞENYÜZ
Amaç: Bu çalışmada, portal hipertansiyonlu çocuk hastalarda, portal hipertansiyon ve tedavi edici girişimlerin gastroözofageal reflühastalığı ile ilişkisini araştırmak hedeflendi.Gereç ve Yöntemler: Çalışmaya 30 portal hipertansiyonlu çocuk hasta alındı. Hastalar üç ana gruba ayrıldı;Grup 1: Endoskopik skleroterapi uygulanmamış olgular.Grup 2: Endoskopik skleroterapi programında olan olgular.Grup 3: Devaskülarizasyon ameliyatı yapılan olgular.Hastaların gastroözofageal reflü şikayetleri, endoskopi ve 24 saatlik pH monitorizasyonu bulguları kaydedildi. İstatistiksel inceleme Fisher-Exact yöntemi ile yapıldı.Bulgular: Çalışmada portal hipertansiyonlu olgularda, üç incelemede de, gastroözofageal reflü toplumdakine oranla belirgin olarak fazlagörüldü. Klinik reflü göz önüne alındığında gruplar arasında anlamlı fark bulunmadı. Endoskopi bulguları göz önüne alındığında Grup 1 ve3’te Grup 2’ye göre anlamlı olarak fazla saptandı. Buna karşılık 24 saatlik pH metre incelemelerinde, gruplar arası anlamlı fark bulunmadı.Sonuç: Portal hipertansif olgulardaki gastroözofageal reflü araştırmasında tek bir yöntem yeterli değildir. Klinik belirti ve bulgular, endoskopik muayene ve pH monitorizasyonu birlikte değerlendirilmelidir. Yüksek reflü oranı nedeni ile tüm portal hipertansif çocuklarıntedavi altına alınması akılcı bir yaklaşım olarak görülmektedir.
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Tuğba ARPA, Ayşen Kutan FENERCİOĞLU, Nurver Turfaner SİPAHİOĞLU
Tuğba ARPA, Ayşen Kutan FENERCİOĞLU, Nurver Turfaner SİPAHİOĞLU
Systemic lupus erythematosus may present with different clinical signs such as fatigue, fever, dermatitis, photosensitivity, alopecia,arthritis, serositis, hematological abnormalities, mucosal ulcerations, Raynaud phenomenon, neurological disease, and glomerulonephritis. Rarely, kidney involvement with the absence of antinuclear antibody (ANA) positivity may be the first and only finding insystemic lupus erythematosus. Since renal involvement affects prognosis negatively, delays in diagnosis and treatment can cause anincrease in mortality and morbidity. In this article, we presented an interesting case of systemic lupus erythematosus, who applied tothe family medicine outpatient clinic with periorbital edema in whom we considered renal involvement and determined histopathological findings that were compatible with lupus nephritis despite the absence of ANA positivity
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Asiye PEREK, Nurdan ALTAN, Yağmur Özge Turaç KÖSEM, Onur TUTAR, Vedat DURGUN
Asiye PEREK, Nurdan ALTAN, Yağmur Özge Turaç KÖSEM, Onur TUTAR, Vedat DURGUN
Ligamentum falciforme separates liver from the left lateral and medial segments along the umbilical fissure and suspends the liveron the anterior wall of the abdomen. The ligamentum teres hepatis is a remnant of the obliterated umbilical vein, which lies on thefree edge of the falciform ligament. Moreover, it contains paraumbilical venules, muscle fibers, various fatty tissue amounts, andtwo mesothelial layers. Pathologies of the falciform ligament are considerably rare. The ligament is usually secondarily affected bysurrounding inflammatory diseases. Because of its rarity, necrosis, or abscess of the falciform ligament is usually misdiagnosed as anabdominal wall abscess, and inappropriate treatment leads to the lesion’s persistence and complications. Surgical resection is thetherapy of choice. The main purpose is to remind that respiratory problems can be the primary complaint of the patient who appliesto the emergency room with falciform necrosis secondary to acute pancreatitis.
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Anıl DEMİRÖZ, Başak DAĞHAN, Tuğba Feryal Yıldız DEĞER, Arif TÜRKMEN
Anıl DEMİRÖZ, Başak DAĞHAN, Tuğba Feryal Yıldız DEĞER, Arif TÜRKMEN
Objective: Breast is one of the secondary sex characters defining gender. It would be an appropriate approach for breast surgeons toevaluate the breast aesthetically when performing aesthetic and reconstructive breast procedures.Methods: Four different women with different breast sizes and shapes were selected. A questionnaire form was prepared with the photostaken from the front and right obliques of these four different women. The participants were asked to evaluate the symmetry, shape, andsize of the breasts by looking at the photos and to determine and interpret the attractiveness score.Results: The participants were 430 men and 570 women. The B cup breast received the highest attractiveness score among the modelsin all the groups. Sagging has been the most commented and criticized parameter.Conclusion: In this study, we aimed to evaluate the aesthetic perspective of breast in our society and believe that it is beneficial in termsof understanding the patient’s expectations, guiding her correctly, and improving what we can do as surgeons.
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Gizem DURCAN, Kenan BARUT, Fatih HASLAK, Mehmet YILDIZ, M. Tayyib KADAK, Amra ADROVİC, Sezgin ŞAHİN, Burak DOĞANGÜN, Özgür KASAPÇOPUR
Gizem DURCAN, Kenan BARUT, Fatih HASLAK, Mehmet YILDIZ, M. Tayyib KADAK, Amra ADROVİC,
... Devamını oku
Objective: Health-related quality of life (HRQOL) is a concept that assesses the effects of physical symptoms, functional status, andcurrent illness on psychological and social functioning. In this study, we aimed to examine the quality of life in children and adolescentswith familial Mediterranean fever (FMF) according to personal and disease-related factors.Methods: A total of 257 children and adolescents with FMF aged 8–18 years were included in the study. The Juvenile Auto-inflammatory Disease Multidimensional Assessment Report was used for assessment of functional ability (self-report scale), pain (visual analog scale - VAS), therapeutic compliance, and HRQOL (physical, social, school, and emotional status). An increase in all subscale scores indicated a worsening.Results: The mean age of the patients was 12.4±2.63 years, and 132 (51.4%) of them were women. In adolescents, HRQOL-general,-social, -school, and -emotional scores were higher than children (p<0.001 for all). Also, all HRQOL subscale scores of females weresignificantly higher than males (p<0.05 for all). Patients who had an attack in the last month had higher functional ability, pain, and allHRQOL subscale scores. However, patients with and without exertional leg pain had similar results in terms of all HRQOL subscales. TheVAS pain score was positively correlated with HRQOL-general, -physical, -school, and -emotional scores. The therapeutic compliancescores were positively weakly correlated with all HRQOL subscales other than HRQOL-physical.Conclusion: This study showed that the quality of life was worse in the adolescent age group, female gender, and the presence of attacks
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Ceren ALİŞ, Ayşegül GÜNDÜZ, Güneş KIZILTAN, Hülya APAYDIN
Ceren ALİŞ, Ayşegül GÜNDÜZ, Güneş KIZILTAN, Hülya APAYDIN
Herein, we report a patient with dementia, parkinsonism, and motor neuron disease owing to possible central nervous system involvement of Whipple disease. Although co-existence of dementia, parkinsonism, and second-order motor neuron involvement may be seenin some degenerative disease complexes, excluding a reversible condition is a necessity. The critical issue in diagnosing our patient wasthe presence of gastroparesis and arthritis in history associated with progressive supranuclear palsy-like clinical features. Impairment inany domain of cognition may be observed in Whipple disease. Our patient had prominent attention and memory deficits. To our knowledge, this is the first case of generalized lower motor neuron involvement with cognitive deficits and parkinsonism in Whipple disease.
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Asiye PEREK, Müge YURDACAN, Yunus Emre BÖLÜKOĞLU, Vedat DURGUN
Asiye PEREK, Müge YURDACAN, Yunus Emre BÖLÜKOĞLU, Vedat DURGUN
Epidermal cysts are located subcutaneously and intradermally as well as in deeper anatomical areas, and they are the most common typeof cysts in the subcutaneous tissue. They are typically small and are considered to be slow-growing palpable masses. The size of epidermal cysts is usually less than 5 cm. They may occur in any part of the body, especially on the head, neck, and trunk. We present a caseof a 30-year-old woman with a giant mass in her right gluteal region. Magnetic resonance imaging and ultrasonography were performed.They revealed a large cystic lesion measuring 16×13×8 cm. The sac and all of its contents were excised under general anesthesia. To ourknowledge, it is the largest epidermal inclusion cyst reported in the Turkish literature.
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Barış KÜÇÜKYÜRÜK, Emine TAŞKIRAN
Barış KÜÇÜKYÜRÜK, Emine TAŞKIRAN
Objective: Intraoperative neurophysiological monitoring (IONM) is commonly used in preserving the function of the facial nerve (FN)during surgery for cerebellopontine angle (CPA) lesions. In this study, we aimed to compare the outcomes of FN function in patients whowere treated for CPA lesions with or without IONM.Methods: This study included 37 patients (22 women, 15 men). The patients were divided in two groups based on whether IONM wasused (group 1) or not (group 2). The FN function was graded according to House–Brackmann (HB) Score. HB scores of 1–3 and 4–6 wereconsidered favorable and unfavorable outcomes, respectively. Demographic information, surgical resection rates, type of pathology, andFN function were evaluated retrospectively. Comparisons between groups were conducted using nonparametric tests.Results: The mean age of the patient group was 45.2±14.82 years and the range was 16–72 years. There were 17 patients in group 1and 20 patients in group 2. At the 1-year examination, 6 patients (35.3%) in group 1 and 2 patients (10%) in group 2 had unfavorableFN function. A 1-year postoperative comparison of the groups, in terms of the presence of disfiguring FN palsy, showed a statisticallysignificant difference (p=0.03).Conclusion: The use of IONM during surgery of CPA lesions promoted the preservation of FN function with a secondary benefit of facilitating maximal resection.
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