Yıl: 2008 Cilt: 19 Sayı: 4 Sayfa Aralığı: 435 - 446 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon

Öz:
Amaç: Omurganın instabilitesine yol açan, omurga destrüksiyonu ve nöral bozuklukların eşlik ettiği tüberküloz spondilit vakalarının cerrahi tedavisinde, anterior radikal debridman ve anterior destek greftlemeden oluşan Hong Kong prosedürü altın standarttır. Son yıllarda artan anterior enstrümantasyon uygulamalarının sonuçlarına ait yayınlarda birden fazla omur seviyesi tutulumunda, tekniğin yetersiz kaldığı bu nedenle bu vakalarda posterior enstrümantasyonla füzyon sahasının korunması önerilmektedir. Prospektif randomize olarak planlanan bu çalışmada, vida – çift rod ile anteriordan enstrümante edilen, birden fazla mobil segmentin tutulumu olan 45 hastanın minimum 5 yıllık sonuçları değerlendirilmesi amaçlanmıştır.Yöntem: Radyolojik olarak kifotik açılanma, global kifoz, klinik olarak SRS – 22 skorları preoperatif, postoperatif ve son kontrollerde belirlenerek mukayese edilmiştir.Bulgular: Preoperatif ortalama 23.9° ± 12.1° olan lokal kifoz açısının postoperatif ortalama 3.2° ± 4.1°’ye indirildiği ve ortalama % 86.0 ± 16.7 korreksiyon oranı sağlandığı, bu düzelmenin istatistiki olarak anlamlı olduğu belirlenmiştir (p < 0.05). Postoperatif korreksiyon oranları ile karşılaştırıldığında istatistiki olarak farksız olacak şekilde son kontrolde % 81.0 ± 18.1 final korreksiyon oranı elde edildiği ve minimal bir korreksiyon kaybı olduğu saptanmıştır. Hastaların tamamında fizyolojik sınırlarda torakal kifoz açılarının elde edildiği de görülmüştür. Preoperatif ağrı, mental durum, görünüm, fonksiyon ve tedaviden tatmin düzeylerinde istatistiki olarak anlamlı bir düzelme sağlanarak, hastaların tamamında son kontrolde tatmin edici sonuç sayılan 4 ve üzeri skorlara sahip oldukları belirlenmiştir. Hastaların tamamında solid füzyon kitlesi elde edilmiş, erken veya geç lokal veya sistemik komplikasyona, enfeksiyonun nüksü veya reaktivasyonuna rastlanmamıştır.Sonuç: Bu çalışmanın verileri ışığında, tüberküloz spondilitte iki veya daha çok tutulumu olan hastalarda da, anterior çift rod-vida sistemi ile uzun fiksasyonun güvenle uygulanabileceği ve yüksek korreksiyon oranları, minimal korreksiyon kayıpları ile başarılı sonuçlar alınabildiği fikri elde edilmiştir.
Anahtar Kelime: Tüberküloz, spinal Kemik hastalıkları, enfeksiyöz İleriye dönük çalışma enstrümantasyon Tüberküloz, osteroartiküler Rastgele kontrollü çalışmalar Spondilit

Konular: Cerrahi

Anterior instrumentation in multiple segment tuberculosis spondylitis

Öz:
Aim: Hong Kong procedure that consits of radical debridement and strut grafting is the gold standard in the surgical treatment of tuberculosis spondylitis cases that associated with spinal instability, deformity and neural defects. In recent literature about anterior instrumentations, posterior instrumentation is recommended in multipl spinal involvement to protect the fusion area because of inadequate anterior techniques. In this prospective randomised study, we investigated the minimum 5 years results of screw &#8211; dual rod anterior instrumentation in 45 patients that had multipl mobile segment involvement. Method: Radiologically kyphotic angulation, global kyphosis and clinically SRS-22 scores were determined in preoperatively, postoperatively and at last follow-ups and these datas were compared. Results: The mean preoperative kyphosis angle was decreased from 23.9° ± 12.1° to 3.2° ± 4.1° postoperatively that shows average 86.0 ± 16.7 % correction rates and it is found statistically significant (p < 0.05). Physiologic thoracic kyphosis angles obtained in all of the patients. 4 or more scores obtained in SRS-22 questionnaire showed satisfactory results at the last followup in all patients, and statistically significant improvements obtained in preoperative pain, mental status, appareance, function and satisfaction from treatment. All patients demonstrated solid fusion mass without early or late local or systemic complications, recurrence and reactivation. Conclusion: According to the datas of this study it is thought that satisfactory results can be obtained with long fixation with anterior dual rod- screw system safely and high correction rates with minimal correction loss in tuberculosis spondylitis patients that have two or more segment involvement.
Anahtar Kelime: instrumentation Tuberculosis, Osteoarticular Randomized Controlled Trial Spondylitis Tuberculosis, Spinal Bone Diseases, Infectious Prospective Studies

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1- Aksoy MC, Acaroglu RE, Tokgozoglu AM, Ozdemir N, Surat A. Retrospective evaluation of treatment methods in tuberculosis spondylitis. Hacettepe J Orthop Surg 1995; 5:207-209.
  • 2- Alanay A, Cil A, Berk H, Acaroğlu RA, Yazıcı M, Akcalı O, Kosay C, Genc Y, Surat. Reliability and validity of adapted Turkish version of Scoliosis Research Society-22 (SRS-22) questionnaire. Spine 2005; 30 (21): 2464-2468.
  • 3- Benhardt, M. Normal spinal anatomy: normal sagittal plane alignment. In: Bridwell, K.H., DeWald, R.L., eds. The Text Book of Spinal Surgery, Philadelphia, Lippincott -Raven Publishers, 1997: 188-189.
  • 4- Benli IT, Aydın E, Kis M, Akaşlın S, Tuzuner M, Baz AB. The results of anterior instrumentation in vertebral tuberculosis. J. Turkish Spine Surg 1996; 7(3):98-101.
  • 5- Benli IT, Akalin S, Kis M, Citak M, Kurtulus B, Duman E. The results of anterior fusion and Cotrel – Dubousset – Hopf instrumentation in idiopathic scoliosis. Eur Spine J 2000; 9(6): 5005-515.
  • 6- Benli IT, Kis M, Akal›n S, Citak M, Kanevetci S, Duman E. The results of anterior radical debridement and anterior instrumentation in Pott's disease and comparison with other surgical techniques. Kobe J Med Sci 2000; 46: 39 –68.
  • 7- Benli IT, Acaroglu E, Akalin S, Kis M, Duman E, Un A. Anterior radical debridement and anterior instrumentation in tubercolous spondylitis. Eur Spine J 2003; 12: 224 – 234.
  • 8- Benli IT, Alanay A, Akalın S. Kış M, Acaroğlu E, Atefl B, Aydın E. Comparison of anterior instrumentation systems and the results of minimum 5 years follow-up in the treatment of tuberculosis spondylitis. Kobe J Med Sci 2005; 50 (5-6): 167-180.
  • 9- Benli İT, Kaya A, Acaro¤lu E. Anterior instrumentation in tuberculosis spondylitis. Is it effective and safe? Clin Orthop Rel Res 2007, 460: 108-116.
  • 10-Dai LY, Jiang LS, Wang W, Cui YM. Single – stage anterior autogenous bone grafting and instrumentation in the surgical management of spinal tuberculosis. Spine 2005; 30 (20): 2342-2349.
  • 11- Dick JC, Brodke DS, Zdeblick TA, et al. Anterior instrumentation of the thoracolumbar spine. Spine 1997; 22: 744-50.
  • 12- Domanic U, Hamzaoglu A, Sar C, Yavuzer Y. Posterior fusion and instrumentation after anterior radical debridement and fusion in the surgical treatment of Pott's disease. J Turkish Spine Surg 1993; 4(1): 16-19.
  • 13- Dunn HK. Anterior stabilization of thoracolumbar injuries. Clin Orthop 1984; 189: 116-24.
  • 14- Faro FD, White KK, Ahn JS, Oka RS, Mahar AT, Bawa M, Farmsworth CL, Garfin SR, Newton PO. Biomechanical analysis of anterior instrumentation for lumbar corpectomy. Spine 2003; 28 (22): E468-471.
  • 15- Frankel HL, Hancock DO, Hyslop G, Melzah J, Michaelis LS, Ungar GH, Vernon JD, Walsh JJ. The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. Paraplegia 1969; 7:179-192.
  • 16- Guven O, Kumano K, Yasin S, Karahan M, Tsuji S. A single stage posterior approach and rigid fixation for preventing kyphosis in the treatment of spinal tuberculosis. Spine 1994;19:1039-1043.
  • 17- Harris, MB, Thomas KA, Igram CM, et al. The effect of anterior thoracolumbar plate application on the compressive loading of the strut graft. Spine 1996; 21: 1487-93.
  • 18- Hodgson AR, Stock FE, Forg HSY, Ong GB. Anterior spinal fusion: the operative approach and pathological findings in 412 patients with Pott’s disease of the spine. Br J Surg 1960; 48: 172-178.
  • 19- Hodgson AR, Stock FE. Anterior spinal fusion. A preliminary communication on the radical treatment of Pott's disease and Pott paraplegia. Clin Orthop 1994; 300: 16-23.
  • 20- Hsu LC, Cheng CL, Leong JC. Pott’s paraplegia of late onset: The cause of compression and results after anterior decompression. J Bone Joint Surg 1988; 70-B: 534-538.
  • 21- Hopf C, Eysel P, Dubousset J. CDH: Preliminary report on new anterior spinal instrumentation. Eur Spine J 1995; 4: 194-199.
  • 22- Kaneda K, Abumi K, Fujiya M. Burst fractures with neurologic deficits of the thoracolumbarlumbar spine. Results of anterior decompression and stabilization with anterior instrumentation. Spine 1984; 9: 788-95.
  • 23- Kemp HBS, Jackson JW, Jeremiah JD, Cook J. Anterior fusion of the spine for infective lesions in adults. J Bone Joint Surg 1973; 55-B: 715-734.
  • 24- Korkusuz F, Islam C, Korkusuz Z. Prevention of postoperative late kyphosis in Pott's disease by anterior decompression and intervertebral grafting. World J Surg 1997; 21(5): 524-528.
  • 25- Kostuik JP. Anterior spinal cord decompression for lesions of the thoracic and lumbar spine: Techniques, new methods of internal fixation. Spine 1983; 8:512-531.
  • 26- Loembe PM. Medical -surgical treatment of progressive tuberculous (Pott's) paraplegia in Gabon. Paraplegia 1995; 33(10): 579-584.
  • 27- McCullen G, Vaccaro AR, Garfin SR. Thoracic and lumbar trauma: rationale for selecting the appropriate fusion technnique. Orthop Clin North Am 1998; 29: 813-28.
  • 28- Medical Research Council Working Party or Tuberculosis of the Spine. A 15 -year assessment of controlled trials of the management of tuberculosis of the spine in Korea and Hong Kong. Thirteenth Report of the Medical Research Council Working Party on Tuberculosis of the Spine. J Bone Joint Surg 1998; 80-B(3): 456-462.
  • 29- Medical Research Council Working Party on Tuberculosis of the Spine. Five-year assessment of controlled trials of short -course chemotherapy regimens of 6, 9 or 18 months' duration for spinal tuberculosis in patients ambulatory from the start or undergoing radical surgery. Fourteenth report of the Medical Research Council Working Party on Tuberculosis of the Spine. Int Orthop 1999; 23(2):73-81.
  • 30- Medical Research Council Working Party or Tuberculosis of the Spine. A 15 -year assessment of controlled trials of the management of tuberculosis of the spine in Korea and Hong Kong. Thirteenth Report of the Medical Research Council Working Party on Tuberculosis of the Spine. J Bone Joint Surg 1998; 80-B(3): 456-462.
  • 31- Moon M S. Spine 1998 update: tuberculosis of the spine. Spine 1997; 22 (15): 1791-1797.
  • 32- Moula T, Fowles JV, Kassab MT, Sliman N. Pott's paraplegia: a clinical review of operative and conservative treatment in 63 adults and children. Int Orthop 1981; 5(1): 23-29.
  • 33- Nemir RL, Krasinski K. Tuberculosis in children and adolescents in the 1980s. Pediatr Infect Dis J 1988; 7 (6): 375-379.
  • 34- Oga M, Arizono T, Takasita M, Sugioka Y. Evaluation of the risk of instrumentation as a foreign body in spinal tuberculosis: Clinical and biologic study. Spine 1993; 18: 1890-1894.
  • 35- Ozdemir HM, Us AK, Ogun T. The role of anterior spinal instrumentation and allograft fibula for the treatment of Pott’s disease. Spine 2003; 28 (5): 474 – 479.
  • 36- Rajasekaran S, Soundarapandian S. Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis. J Bone Joint Surg 1989; 71-A: 1314-1323.
  • 37- Rezai AR, Lee M, Cooper PR, Errico TJ, Koslow M. Modern management of spinal tuberculosis. Neurosurgery 1995; 36 (1): 87-97.
  • 38- Schulitz KP, Kothe R, Leong JCY, Wehling P. Growth changes of solid fusion kyphotic bloc after surgery for tuberculosis. Spine 1997; 22 (10): 1150-1155.
  • 39- Shimamoto N, Kotani Y, Shono Y, et al. Biomechanical evaluation of anterior spinal instrumentation systems for scoliosis: in vitro fatigue simulation. Spine 2001; 26: 2701-2708.
  • 40- Slucky AV, Eismont FJ. Spinal infections. In: Bridwell KH, DeWald RL, Eds., The Textbook of Spinal Surgery, Philadelphia, Lippincott -Raven Publishers. 1997 : 2141-2183.
  • 41- Tuli SM. Current concept. Severe kyphotic deformity in tuberculosis of the spine. Int Orthop 1995; 19: 327-331.
  • 42- Upadhyay SS, Sell P, Saji MJ, Sell B, Hsu LC. Surgical management of spinal tuberculosis in adults: Hong Kong operation compared with debridement surgery for short and long term outcome of deformity. Clin Orthop Rel Res 1994; 302: 173-182.
  • 43- Upadhyay SS, Saji MJ, Yau ACMC. Duration of antituberculous chemotherapy in conjunction with radical surgery in the management of spinal tuberculosis. Spine 1996; 21: 1898-1903.
  • 44- Yau ACMC, Hsu LCS, O'Brein JP, Hodgson AR. Tuberculosis kyphosis: correction with spinal osteotomy halopelvis distraction and anterior and posterior fusion. J Bone Joint Surg 1974; 56-A: 1419-1434.
  • 45- Yilmaz C, Selek HY, Gurkan I, Erdemli B, Korkusuz Z. Anterior instrumentation for the treatment of spinal tuberculosis. J Bone Joint Surg 1999; 81-A (9): 1261-1267.
APA BENLİ İ, KAYA A, GÜÇLÜ B (2008). Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. , 435 - 446.
Chicago BENLİ İ. Teoman,KAYA Alper,GÜÇLÜ BERK Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. (2008): 435 - 446.
MLA BENLİ İ. Teoman,KAYA Alper,GÜÇLÜ BERK Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. , 2008, ss.435 - 446.
AMA BENLİ İ,KAYA A,GÜÇLÜ B Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. . 2008; 435 - 446.
Vancouver BENLİ İ,KAYA A,GÜÇLÜ B Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. . 2008; 435 - 446.
IEEE BENLİ İ,KAYA A,GÜÇLÜ B "Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon." , ss.435 - 446, 2008.
ISNAD BENLİ, İ. Teoman vd. "Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon". (2008), 435-446.
APA BENLİ İ, KAYA A, GÜÇLÜ B (2008). Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. Journal of Turkish Spinal Surgery, 19(4), 435 - 446.
Chicago BENLİ İ. Teoman,KAYA Alper,GÜÇLÜ BERK Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. Journal of Turkish Spinal Surgery 19, no.4 (2008): 435 - 446.
MLA BENLİ İ. Teoman,KAYA Alper,GÜÇLÜ BERK Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. Journal of Turkish Spinal Surgery, vol.19, no.4, 2008, ss.435 - 446.
AMA BENLİ İ,KAYA A,GÜÇLÜ B Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. Journal of Turkish Spinal Surgery. 2008; 19(4): 435 - 446.
Vancouver BENLİ İ,KAYA A,GÜÇLÜ B Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon. Journal of Turkish Spinal Surgery. 2008; 19(4): 435 - 446.
IEEE BENLİ İ,KAYA A,GÜÇLÜ B "Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon." Journal of Turkish Spinal Surgery, 19, ss.435 - 446, 2008.
ISNAD BENLİ, İ. Teoman vd. "Çoklu seviye tüberküloz spondilitte anterior enstrümantasyon". Journal of Turkish Spinal Surgery 19/4 (2008), 435-446.