REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım

TAŞÇILAR, Nida; Karadeniz, Derya

REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım

Nida TAŞÇILAR, (Zonguldak Karaelmas Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Zonguldak, Türkiye)

Derya KARADENİZ (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye)

Türk Nöroloji Dergisi

26 0

Yıl: 2008 Cilt: 14 Sayı: 2 Sayfa Aralığı: 81 - 91 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım

Öz:

Bilimsel zemin: REM uykusu davranış bozukluğu (RDB) “rüyaların canlandırılması” ve normal REM uykusu kas atonisi kaybıyla karakterize bir parasomnidir. İdiyopatik ya da nörodejeneratif hastalıklarla birlikte gözlenir. “Rüyaların canlandırılması” sıklıkla şiddet veya zarar verici davranışlara neden olur. Bunun sonucunda hastalarda ve yatak arkadaşlarında laserasyon, kırık, subdural hematom gibi yaralanmalar gelişebilir. Gelişmiş ülkelerde, bu davranışların legal sonuçları tıbbi ve hukuksal literatürde tartışılmaktadır. Ancak Türkiye’de RDB’ye hukuksal yaklaşım henüz ele alınmamıştır.YORUM: Bu yazıda RDB’nin kliniği, patofizyolojisi, tedavisi ve medikolegal yaklaşım ele alınmıştır.

Anahtar Kelime: fizyopatoloji Hukuk REM uykusu davranış bozukluğu Tanı, ayırıcı

Konular: Nörolojik Bilimler

REM sleep behavior disorder and medico-legal aspects

Öz:

Scientific BACKGROUND: Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterised by dream-enacting behaviors and loss of normal REM sleep muscle atonia. It could occur idiopathically or accompanying neurodegenerative diseases. “Acting out of dreams” permits violent or injurious behaviors. These behaviors could result in laceration, fractures, subdural haematomas and so on. In developed countries, the legal implications of these behaviors have been discussing and debating in medical and legal literature. But in Turkey, legal aspects of RBD have not discussed yet. CONCLUSION: In this review, the clinic, pathopysiology, therapy and medicolegal aspects of RBD is discussed.

Anahtar Kelime: REM Sleep Behavior Disorder Diagnosis, Differential physiopathology Jurisprudence

Konular: Nörolojik Bilimler

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

1. Mahowald MW, Schenck CH. REM Sleep Parasomnias; Principles and Practice of Sleep Medicine (Kryger MH,eds) Philadelphia, Elsevier Yayın.; 2005;897-916.
2. Olson EJ, Boeve BF, Silber MH. Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain. 2000;123:331-339.
3. Schenck CH, Bundlie SR, Ettinger MG, Mahowald MW. Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep.1986;9(2):293-308.
4. Wolkove N, Elkholy O, Baltzan M, Palayew M. Sleep and aging: 1. Sleep disorders commonly found in older people. CMAJ. 2007;176(9):1299-1304.
5. Rapid eye movement sleep behavior disorder. American Academy of Sleep Medicine; International Classification of Sleep Disorders, 2. baskı.: Diagnostic and coding manual. Westchester, Illinois: American Academy of Sleep Medicine; 2005;148-152.
6. Mahowald MW, Schenck CH. Medical-legal aspects of sleep medicine. Neurol Clinic.1999;17(2):215-234.
7. Iranzo A, Santamaría J, Rye DB, Valldeoriola F, Martí MJ, Muñoz E, Vilaseca I, Tolosa E. Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD. Neurology. 2005;65(2):247-252.
8. Boeve BF, Silber MH, Parisi JE, Dickson DW, Ferman TJ, Benarroch EE, Schmeichel AM, Smith GE, Petersen RC, Ahlskog JE, Matsumoto JY, Knopman DS, Schenck CH, Mahowald MW. Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology. 2003;61:40-45.
9. Arnulf I, Merino-Andreu M, Bloch F, Konofal E, Vidailhet M, Cochen V, Derenne JP, Agid Y. REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy. Sleep. 2005;28(3):349-354.
10. Plazzi G, Montagna P. Remitting REM sleep behavior disorder as the initial sign of multiple sclerosis. Sleep Med. 2002;3:437-439.
11. Fukutake T, Shinotoh H, Nishino H, Ichikawa Y, Goto J, Kanazawa I, Hattori T. Homozygous Machado-Joseph disease presenting as REM sleep behavior disorder and prominent psychiatric symptoms. Eur J Neurol. 2002;9:97-100.
12. Zambelis T, Paparrigopoulos T, Soldatos CR. REM sleep behavior disorder associated with a neurinoma of the left pontocerebellar angle. J Neurol Neurosurg Psychiatry. 2002;72:821-822.
13. Kimura K, Tachibana N, Kohyama J, Otsuka Y, Fukazawa S, Waki R. A discrete pontine ischemic lesion could cause REM sleep behavior disorder. Neurology. 2000;55:894-895.
14. Friedmann JH. Presumed rapid eye movement behavior disorder in Machado-Joseph disease (spinocerebellar ataxia type 3). Mov Disord. 2002;17:1350-1353.
15. Syed BH, Rye DB, Singh G. REM sleep behavior disorder and SCA-3 (Machado-Joseph disease). Neurology. 2003;60:148.
16. Schenck CH, Mahowald MW. Polysomnographic, neurologic, psychiatric, and clinical outcome report on 70 consecutive cases with REM sleep behavior disorder (RBD): Sustained clonazepam efficacy in 89,5% of 57 treated patients. Cleve Clin J Med. 1990;57(Suppl):S9-S23.
17. Iranzo A, Graus F, Clover L, Morera J, Bruna J, Vilar C, Martínez Rodriguez JE, Vincent A, Santamaría J. Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. Ann Neurol. 2006;59:178-181.
18. Tippmann-Peikert M, Boeve BF, Keegan BM. REM sleep behavior disorder initiated by acute brainstem multiple sclerosis. Neurology. 2006;66(8):1277-1279.
19. Kumru H, Santamaria J, Tolosa E, Valldeoriola F, Muñoz E, Marti MJ, Iranzo A. Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations. Ann Neurol. 2004;56(4):599-603.
20. Trajanovic NN, Voloh I, Shapiro CM, Sandor P. REM sleep behaviour disorder in a child with Tourette’s syndrome. Can J Neurol Sci. 2004;31(4):572-575.
21. Mathis J, Hess CW, Bassetti C. Isolated mediotegmental lesion causing narcolepsy and rapid eye movement sleep behaviour disorder: a case evidencing a common pathway in narcolepsy and rapid eye movement sleep behaviour disorder. J Neurol Neurosurg Psychiatry. 2007;78(4):427-429.
22. Anderson K, Shneerson J, Smith I. Möbius syndrome in association with the REM sleep behaviour disorder. J Neurol Neurosurg Psychiatry. 2007;78(6):659-660.
23. Verma A, Anand V, Verma NP. Sleep disorders in chronic traumatic brain injury. J Clin Sleep Med. 2007;3(4):357-362. (abstract)
24. Dauvilliers Y, Rompré S, Gagnon JF, Vendette M, Petit D, Montplaisir J. REM sleep characteristics in narcolepsy and REM sleep behavior disorder. Sleep. 2007;30(7):844-849.
25. Hickey MG, Demaerschalk BM, Caselli RJ, Parish JM, Wingerchuk DM. “Idiopathic” rapid-eye-movement (REM) sleep behavior disorder is associated with future development of neurodegenerative diseases. Neurologist. 2007;13(2):98-101.
26. Gagnon JF, Postuma RB, Mazza S, Doyon J, Montplaisir J. Rapid-eyemovement sleep behaviour disorder and neurodegenerative diseases. Lancet Neurol. 2006;5(5):424-432.
27. Iranzo A, Molinuevo JL, SantamaríaJ, Serradell M, Martí MJ, Valldeoriola F, Tolosa E. Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol. 2006;5(7):572-577.
28. Postuma RB, Montplaisir J. Potential early markers of Parkinson’s disease in idiopathic rapid-eye-movement sleep behaviour disorder. Lancet Neurol. 2006;5(7):552-3.
29. Comella CL, Nardine TM, Diederich NJ, Stebbins GT. Sleep-related violence, injury, and REM sleep behavior disorder in Parkinson’s disease.Neurology. 1998;51:526-529.
30. Webster HH, Friedman L, Jones BE. Modification of paradoxical sleep following transections of the reticular formation at the pontomedullary junction. Sleep. 1986;9(1):1-23.
31. Hendricks JC, Morrison AR, Mann GL. Different behaviors during paradoxical sleep without atonia depend on pontine lesion site. Brain Res. 1982;239:81-105.
32. Mahowald MW, Schenck CH. REM sleep without atonia—from cats to humans. Arch Ital Biol. 2004;142(4):469-478.(abstract).
33. Mahowald MW, Schenck CH. REM sleep behavior disorder; Clinical Neurophysiology of Sleep Disorders Handbook of Clinical Neurophysiology Vol 6 (Guilleminault C,ed) Amsterdam, Elsevier Yay›n.; 2005;245-253.
34. Hirshkowitz M, Sharafkhaneh A. The physiology of sleep.Clinical Neurophysiology of Sleep Disorders Handbook of Clinical Neurophysiology Vol 6 (Guilleminault C,ed) Amsterdam, Elsevier Yay›n.; 2005;3-20.
35. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. BIS/BRI, UCLA, Los Angeles, 1968.
36. Dyken ME, Lin-Dyken DC, Seaba P, Yamada T. Violent sleep-related behavior leading to subdural hemorrhage. Arch Neurol. 1995;52:318-321.
37. Morfis L, Schwartz RS, Cistulli PA. REM sleep behavior disorder; a treatable cause of falls in elderly peopple. Age Ageing.1997;26:43-44.
38. Mahowald MW, Schenck CH. Parasomnias: sleepwalking and the law. Sleep Med Rev. 2000;4(4):321-339.
39. Mahowald MW, Schenck CH. Violent Parasomnias: Forensic Medicine Issues; Principles and Practice of Sleep Medicine (Kryger MH, eds) Philadelphia, Elsevier Yay›n.; 2005;960-968.
40. Schenck CH. [Aydın H, Karacan i (Çeviri Ed)] Uykuda Çözülen Paradoks.Ankara, HYB Yayın.; 2006.
41. Broughton R, Billings R, Cartwright R, Doucette D, Edmeads J, Edwardh M, Ervin F, Orchard B, Hill R, Turrell G Homicidal Somnambulism: A case report. Sleep. 1994;17(3):253-264.
42. Bornemann MAC, Mahowald MW, Schenck CH. Parasomnias Clinical features and forensic implications. Chest. 2006;130(2):605-610.
43. Nofzinger EA, WettsteinRM. Homicidal behavior and sleep apnea; a case report and medicolegal discussion. Sleep. 1995;18(9):776-782.
44. Özkan M, Hakeri H. Ceza Hukuku ve Ruhsal Bozukluklar. KHukA (Kamu Hukuku Arşivi). 1998;2:89-99.
45. Türk Ceza Kanunu 5237, kanun numarası:5237, kabul tarihi:12.10.2004, yayınlandığı resmi gazete 25611.
46. Sinforiani E, Zangaglia R, Manni R, Cristina S, Marchioni E, Nappi G, Mancini F, Pacchetti C. REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson’s disease. Mov Disord. 2006;21(4):462-466.
47. Schmidt MH, Koshal VB, Schmidt HS. Use of pramipexola in REM sleep behavior disorder: results from a case series. Sleep Med. 2006;7(5):418-423.

APA	TAŞÇILAR N, Karadeniz D (2008). REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. , 81 - 91.
Chicago	TAŞÇILAR Nida,Karadeniz Derya REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. (2008): 81 - 91.
MLA	TAŞÇILAR Nida,Karadeniz Derya REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. , 2008, ss.81 - 91.
AMA	TAŞÇILAR N,Karadeniz D REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. . 2008; 81 - 91.
Vancouver	TAŞÇILAR N,Karadeniz D REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. . 2008; 81 - 91.
IEEE	TAŞÇILAR N,Karadeniz D "REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım." , ss.81 - 91, 2008.
ISNAD	TAŞÇILAR, Nida - Karadeniz, Derya. "REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım". (2008), 81-91.

APA	TAŞÇILAR N, Karadeniz D (2008). REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. Türk Nöroloji Dergisi, 14(2), 81 - 91.
Chicago	TAŞÇILAR Nida,Karadeniz Derya REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. Türk Nöroloji Dergisi 14, no.2 (2008): 81 - 91.
MLA	TAŞÇILAR Nida,Karadeniz Derya REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. Türk Nöroloji Dergisi, vol.14, no.2, 2008, ss.81 - 91.
AMA	TAŞÇILAR N,Karadeniz D REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. Türk Nöroloji Dergisi. 2008; 14(2): 81 - 91.
Vancouver	TAŞÇILAR N,Karadeniz D REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım. Türk Nöroloji Dergisi. 2008; 14(2): 81 - 91.
IEEE	TAŞÇILAR N,Karadeniz D "REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım." Türk Nöroloji Dergisi, 14, ss.81 - 91, 2008.
ISNAD	TAŞÇILAR, Nida - Karadeniz, Derya. "REM uykusu davranış bozukluğu (RDB) ve mediko-legal yaklaşım". Türk Nöroloji Dergisi 14/2 (2008), 81-91.