Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?

OLIVIER, Andre; TANRIVERDİ, Taner; KLEIN, Denise; MOK, Kelvin; POULIN, Nicole; AL HINAI, Qasim

Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?

Taner TANRIVERDİ, (Montreal Neurological Inst., Montreal/Quebec, Canada)

Qasim AL HINAI, (Montreal Neurological Inst., Montreal/Quebec, Canada)

Kelvin MOK, (Montreal Neurological Inst., Montreal/Quebec, Canada)

Denise KLEIN, (Montreal Neurological Inst., Montreal/Quebec, Canada)

Nicole POULIN, (Montreal Neurological Inst., Montreal/Quebec, Canada)

Andre OLIVIER (Montreal Neurological Inst., Montreal/Quebec, Canada)

Turkish Neurosurgery

2 0

Yıl: 2009 Cilt: 19 Sayı: 1 Sayfa Aralığı: 1 - 14 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?

Öz:

AMAÇ: Sol hipokampal sklerozlu hastaların pozitron emisyon tomografilerindeki atipik konuşma (sağ veya bilateral) aktivasyonları hakkında bilgi vermek.YÖNTEM ve GEREÇ: Sol hipokampal skleroz nedeniyle ameliyat edilmiş olan 12 sağlak hasta ile 12 sağlıklı sağlak kişiler çalışmaya dahil edildi ve konuşma aktivasyonlarının değerlendirilmesi için eşanlamlı sözcük bulma testi kullanıldı.BULGULAR: Kontrol grubu ile karşılaştırıldığında atipik konuşma aktivasyonları hasta grubunda daha fazla oranla bulundu. Kontrol grubunda toplam 3 kişide (%25) atipik konuşma aktivasyonları görüldü: 2 kişide bilateral sağ ve 1 kişide de bilateral sol ağırlıklı aktivasyonlar. Kontrol grubunda sağ taraflı Broka aktivasyonu görülmezken hastalarda %25 oranında görüldü. Hastalarda atipik konuşma aktivasyonu insidansı %91.6 (11 hasta) olarak bulundu.SONUÇ: Bu çalışma açıkça ortaya koymuştur ki sol hipokampal sklerozlu hastalarda lisan ile ilgili sinir sistemi ağında yeniden yapılanma olmaktadır. Lezyon, primer lisan bölgelerinden uzakta da olsa bu hastalarda atipik lisan aktivasyonları görülmektedir ve bu husus ameliyattan önce dikkate alınmalıdır.

Anahtar Kelime: Konuşma Pozitron-emisyon tomografi ve bilgisayarlı tomografi Hipokampus Baskınlık, serebral Nöral plastisite Skleroz

Konular: Cerrahi

Sol hipokampal sklerozlu hastalarda atipik konuşma lateralizasyonu: Hipokampus konuşma lateralizasyonunu etkiler mi?

Öz:

AIM: To provide information related to atypical language activations (right or bilateral) in positron emission tomography in patients with left clear-cut hippocampal sclerosis.MATERIAL and METHODS: Twelve right-handed patients who had been operated on left-sided hippocampal sclerosis and 12 right-handed normal subjects were included and the synonym generation task was used for evaluation of language lateralization.RESULTS: Atypical language activations were frequently found in the patients compared to the controls. A total of 3 (25%) subjects in the controls showed atypical activations: 2 bilateral with right and 1 bilateral with left-sided activations. There were no clear rightsided Broca activations in the control group but almost 25% of the patients showed clear right-sided Broca activations. In the patients the incidence of atypical language activations was 91.6% (11 patients).CONCLUSION: From the present study, it is clear that functional reorganization of the language-related neuronal network is modified in patients with left hippocampal sclerosis. Although the lesion is far from the primary language-related areas, atypical language lateralization is common in these patients and this should be considered in preoperative period.

Anahtar Kelime: Hippocampus Dominance, Cerebral Neuronal Plasticity Sclerosis Speech Positron-Emission Tomography and Computed Tomography

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TANRIVERDİ T, AL HINAI Q, MOK K, KLEIN D, POULIN N, OLIVIER A (2009). Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. , 1 - 14.
Chicago	TANRIVERDİ Taner,AL HINAI Qasim,MOK Kelvin,KLEIN Denise,POULIN Nicole,OLIVIER Andre Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. (2009): 1 - 14.
MLA	TANRIVERDİ Taner,AL HINAI Qasim,MOK Kelvin,KLEIN Denise,POULIN Nicole,OLIVIER Andre Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. , 2009, ss.1 - 14.
AMA	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. . 2009; 1 - 14.
Vancouver	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. . 2009; 1 - 14.
IEEE	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A "Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?." , ss.1 - 14, 2009.
ISNAD	TANRIVERDİ, Taner vd. "Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?". (2009), 1-14.

APA	TANRIVERDİ T, AL HINAI Q, MOK K, KLEIN D, POULIN N, OLIVIER A (2009). Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. Turkish Neurosurgery, 19(1), 1 - 14.
Chicago	TANRIVERDİ Taner,AL HINAI Qasim,MOK Kelvin,KLEIN Denise,POULIN Nicole,OLIVIER Andre Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. Turkish Neurosurgery 19, no.1 (2009): 1 - 14.
MLA	TANRIVERDİ Taner,AL HINAI Qasim,MOK Kelvin,KLEIN Denise,POULIN Nicole,OLIVIER Andre Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. Turkish Neurosurgery, vol.19, no.1, 2009, ss.1 - 14.
AMA	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. Turkish Neurosurgery. 2009; 19(1): 1 - 14.
Vancouver	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?. Turkish Neurosurgery. 2009; 19(1): 1 - 14.
IEEE	TANRIVERDİ T,AL HINAI Q,MOK K,KLEIN D,POULIN N,OLIVIER A "Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?." Turkish Neurosurgery, 19, ss.1 - 14, 2009.
ISNAD	TANRIVERDİ, Taner vd. "Atypical language lateralization in patients with left hippocampal sclerosis: Does the hippocampus affect language lateralization?". Turkish Neurosurgery 19/1 (2009), 1-14.