Distribution of coronary artery risk factors: a regional analysis
Yıl: 2011 Cilt: 41 Sayı: 2 Sayfa Aralığı: 317 - 324 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Distribution of coronary artery risk factors: a regional analysis
Öz: Amaç: Bu çalışmadaki amacımız, Rize ili ve civarında koroner arter risk faktörlerinin sıklık ve dağılımını incelemektir. Yöntem ve gereç: Bu gözlemsel çalışmaya, 452 hasta (333 erkek, 119 kadın) alındı. Hastaların demografi k özelliklerinin yanı sıra, geleneksel risk faktörleri kaydedildi. Hastalar yaşa, cinsiyete ve elektrokardiyografi k özelliklerine göre gruplara ayrıldı. Bulgular: Çalışmaya katılan hastaların yaş ortalaması 63 ± 13 iken, % 74’ü erkekti. Sigara kullanımı ve HT genç yaşta ve erkeklerde daha fazla görüldü (% 71). Diyabetes mellitusta yaş grupları arasında fark tespit edilmedi. Kadınlarda HDL-C (P < 0,001) ve Total-C/HDL-C oranı (P < 0,05) erkeklere göre daha yüksek bulundu. Sigara kullanımı ve aile hikayesi yaşla birlikte azalma gösterdi. Sonuç: Hastaların % 97’sinde en az bir risk faktörü mevcuttu. Dolayısıyla çalışmamız, en önemli morbidite ve mortalite nedeni olan koroner arter hastalığında, hastalardaki risk faktör değişikliğinin ne kadar önemli olduğunu bizlere tekrar vurgulamaktadır.
Anahtar Kelime: Konular:
Koroner arter hastalığı risk faktörlerinin dağılımı: bölgesel bir analiz
Öz: Aim: To analyze the frequency and distribution of coronary artery risk factors in the city of Rize and its surrounding areas. Materials and methods: Th is observational study included 452 patients (333 men, 119 women). In addition to demographic characteristics of the patients, conventional risk factors were also recorded. Th e patients were grouped according to their ages, gender, and electrocardiographic characteristics. Results: Th e mean age of participants was 63 ± 13 years and 74% were male. Smoking and hypertension (HT) were seen more oft en (71%) in younger male patients. No diff erence among age groups was detected with regard to the occurrence of diabetes mellitus. Th e levels of HDL-cholesterol (P < 0.001) and the ratio of total cholesterol to HDL-cholesterol (P < 0.05) were found to be relatively higher in female patients. Th e prevalence of smoking and familial risk factors both decreased with age. Conclusion: At least one of these risk factors was detected in 97% of patients. Th erefore, our study continues to emphasize the crucial role of modifi cation of risk factors in patients with coronary artery disease, the most important etiologic factor for morbidity and mortality.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. World Health Organization. Th e World Health Report 2002 - Reducing risks to health, promoting healthy life. (http://www. who.int/whr/en)
- 2. Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F et al. INTERHEART Study Investigators. Eff ect of potentially modifi able risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004; 364: 937-52.
- 3. Onat A, Uzunlar B, Hergenç G, Yazıcı M, Uyarel H, Toprak S et al. Distribution of risk variables and global risk across geographic regions of Turkey. Türk Kardiyol Dern Arş 2003; 31: 323-30.
- 4. Turnbull F. Blood Pressure Lowering Treatment Trialists’ Collaboration. Eff ects of diff erent blood pressure-lowering regimens on major cardiovascular events: results of prospectively designed overviews of randomized trials. Lancet 2003; 362: 1527-35.
- 5. Collins R, Armitage J, Parish S, Sleigh P, Peto R. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomized placebo-controlled trial. Lancet 2003; 361: 2005-16.
- 6. de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications aft er myocardial infarction: fi nal report of the Lyon Diet Heart Study. Circulation 1999; 99: 779- 85.
- 7. Parish S, Collins R, Peto R, Youngman L, Barton J, Jayne K et al. Cigarette smoking, tar yields, and non-fatal myocardial infarction: 14,000 cases and 32,000 controls in the United Kingdom. Th e International Studies of Infarct Survival (ISIS) Collaborators. BMJ 1995; 311: 471-7.
- 8. Ermis C, Demir I, Semiz E, Yalcınkaya S, Sancaktar O, Tüzüner FE et al. Antalya Bölgesindeki Koroner Arter Hastalarının Demografi k ve Klinik Özellikleri ve Bu Özelliklerinin Türkiye Ortalamaları ile Karşılaştırılması. Ana Kar Der 2001; 1: 10-13.
- 9. Onat A, Karabulut A, Esen AM, Uyarel H, Ozhan H, Albayrak S et al. Analysis of all-cause mortality and coronary events in the Turkish Adult Risk Factor Survey 2005. Turk Kardiyol Dern Ars 2006; 34: 149-53.
- 10. Grundy SM, Cleeman JI, Merz CN, Brewer HB Jr, Clark LT, Hunninghake DB et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation 2004; 110: 227-39.
- 11. Pyörälä K: CHD prevention in clinical practice. Lancet 1996; 348: 26-8.
- 12. Khot UN, Khot MB, Bajzer CT, Sapp SK, Ohman EM, Brener SJ et al. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 2003; 290: 898-904.
- 13. Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: Th e Bogalusa Heart Study. N Engl J Med 1998; 338: 1650-6.
- 14. Shaw LJ, Bairey Merz CN, Pepine CJ, Reis SE, Bittner V, Kelsey SF et al. WISE Investigators. Insights from the NHLBISponsored Women’s Ischemia Syndrome Evaluation (WISE) Study: Part I: gender diff erences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J Am Coll Cardiol 2006; 47 (3 Suppl): S4-S20.
- 15. Gerber Y, Weston SA, Killian JM, Jacobsen SJ, Roger VL. Sex and classic risk factors aft er myocardial infarction: a community study. Am Heart J 2006; 152: 461-8.
- 16. Barrett-Connor E, Khaw K. Family history of heart attack as an independent predictor of death due to cardiovascular disease. Circulation 1984; 69: 1065-9.
- 17. Sytkowsky PA, D’Agostino RB, Belanger A, Kannel WB. Sex and time trends in cardiovascular disease incidence and mortality: the Framingham Heart Study, 1950-1989. Am J Epidemiol 1996; 143: 338-50.
- 18. Rosengren A, Dotevall A, Eriksson H, Wilhelmsen L. Optimal risk factors in the population: prognosis, prevalence, and secular trends; data from Goteborg population studies. Eur Heart J 2001; 22: 136-44.
- 19. Greenland P, Grundy S, Pasternak RC, Lenfant C. Problems on the pathway from risk assessment to risk reduction. Circulation 1998; 97: 1761-2.
- 20. Onat A, Şurdum-Avcı G, Şenocak M, Örnek E, İşler M, Özışık U et al. Türkiye’de erişkinlerde kalp hastalığı ve risk faktörleri sıklığı taraması: 4. Kanda kolesterol ve trigliserid düzeyleri. Türk Kardiyol Dern Arş 1991; 19: 88-96.
- 21. Onat A, Keleş İ, Çetinkaya A, Başar Ö, Yıldırım B, Erer B et al. On yıllık TEKHARF çalışması verilerine göre Türk erişkinlerinde koroner kökenli ölüm ve olayların prevalansı yüksek. Türk Kardiyol Dern Arş 2001; 29: 8-19.
- 22. Sonmez K, Akcay A, Gencbay M, Akcakoyun M, Demir D, Elönü OH et al. Prevalence of risk factors in patients with angiographically demonstrated coronary artery disease. Turk Kardiyol Dern Ars 2002; 30: 191-8.
- 23. Aygül N, Ozdemir K, Abacı A, Ülkü Aygül M, Düzenli MA, Vatankulu MA et al. Prevalence of risk factors of ST segment elevation myocardial infarction in Turkish patients living in Central Anatolia. Anadolu Kardiyol Derg 2009; 9: 3-8.
- 24. Stamler J, Wentworth D, Neaton JD. Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the multiple risk factor intervention trial (MRFIT). JAMA 1986; 256: 2823-8.
- 25. Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ 2004; 328: 1519-28.
- 26. Mahley RW, Palaoglu KE, Atak Z, Dawson-Pepin J, Langlois AM, Cheung V et al. Turkish heart study: lipids, lipoproteins, and apolipoproteins. J Lipid Res 1995; 36: 839-59.
- 27. Mahley RW, Bersot TP. Low levels of high-density lipoproteins in the Turkish population: A risk factor for coronary heart disease. Türk Kardiyol Dern Arş 1999; 27: 37-43.
- 28. Onat A. Risk factors and cardiovascular disease in Turkey. Atherosclerosis 2001; 156: 1-10.
- 29. Mahley RW, Mahley LL, Bersot TP, Pépin GM, Palaoğlu KE et al. Th e Turkish lipid problem: low levels of high density lipoproteins. Turk J Endocr Metab 2002; 1: 1-12.
- 30. Onat A, Aksu H, Uslu N, Kelefl I, Çetinkaya A, Yıldırım B et al. Smoking among Turkish adults: rising trend in women. Turk Kardiyol Dern Ars 1999; 27: 697-700.
APA | BOSTAN M, ŞATIROĞLU Ö, UYDU H, çiçek y, ÇANĞA A, KARADAĞ Z, TEMİZ A, UĞURLU Y, ATAK M, Bozkurt E (2011). Distribution of coronary artery risk factors: a regional analysis. , 317 - 324. |
Chicago | BOSTAN Mehmet,ŞATIROĞLU Ömer,UYDU HÜSEYİN AVNİ,çiçek yüksel gülen,ÇANĞA Aytun,KARADAĞ Zakir,TEMİZ Ahmet,UĞURLU Yavuz,ATAK MEHTAP,Bozkurt Engin Distribution of coronary artery risk factors: a regional analysis. (2011): 317 - 324. |
MLA | BOSTAN Mehmet,ŞATIROĞLU Ömer,UYDU HÜSEYİN AVNİ,çiçek yüksel gülen,ÇANĞA Aytun,KARADAĞ Zakir,TEMİZ Ahmet,UĞURLU Yavuz,ATAK MEHTAP,Bozkurt Engin Distribution of coronary artery risk factors: a regional analysis. , 2011, ss.317 - 324. |
AMA | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E Distribution of coronary artery risk factors: a regional analysis. . 2011; 317 - 324. |
Vancouver | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E Distribution of coronary artery risk factors: a regional analysis. . 2011; 317 - 324. |
IEEE | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E "Distribution of coronary artery risk factors: a regional analysis." , ss.317 - 324, 2011. |
ISNAD | BOSTAN, Mehmet vd. "Distribution of coronary artery risk factors: a regional analysis". (2011), 317-324. |
APA | BOSTAN M, ŞATIROĞLU Ö, UYDU H, çiçek y, ÇANĞA A, KARADAĞ Z, TEMİZ A, UĞURLU Y, ATAK M, Bozkurt E (2011). Distribution of coronary artery risk factors: a regional analysis. Turkish Journal of Medical Sciences, 41(2), 317 - 324. |
Chicago | BOSTAN Mehmet,ŞATIROĞLU Ömer,UYDU HÜSEYİN AVNİ,çiçek yüksel gülen,ÇANĞA Aytun,KARADAĞ Zakir,TEMİZ Ahmet,UĞURLU Yavuz,ATAK MEHTAP,Bozkurt Engin Distribution of coronary artery risk factors: a regional analysis. Turkish Journal of Medical Sciences 41, no.2 (2011): 317 - 324. |
MLA | BOSTAN Mehmet,ŞATIROĞLU Ömer,UYDU HÜSEYİN AVNİ,çiçek yüksel gülen,ÇANĞA Aytun,KARADAĞ Zakir,TEMİZ Ahmet,UĞURLU Yavuz,ATAK MEHTAP,Bozkurt Engin Distribution of coronary artery risk factors: a regional analysis. Turkish Journal of Medical Sciences, vol.41, no.2, 2011, ss.317 - 324. |
AMA | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E Distribution of coronary artery risk factors: a regional analysis. Turkish Journal of Medical Sciences. 2011; 41(2): 317 - 324. |
Vancouver | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E Distribution of coronary artery risk factors: a regional analysis. Turkish Journal of Medical Sciences. 2011; 41(2): 317 - 324. |
IEEE | BOSTAN M,ŞATIROĞLU Ö,UYDU H,çiçek y,ÇANĞA A,KARADAĞ Z,TEMİZ A,UĞURLU Y,ATAK M,Bozkurt E "Distribution of coronary artery risk factors: a regional analysis." Turkish Journal of Medical Sciences, 41, ss.317 - 324, 2011. |
ISNAD | BOSTAN, Mehmet vd. "Distribution of coronary artery risk factors: a regional analysis". Turkish Journal of Medical Sciences 41/2 (2011), 317-324. |