A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007

ARDA, BİLGİN; YAMAZHAN, Tansu; SİPAHİ, Oğuz Reşat; PULLUKÇU, Hüsnü; Ulusoy, Sercan; TAŞBAKAN, Meltem IŞIKGÖZ

A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007

Meltem IŞIKGÖZ TAŞBAKAN, (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Hüsnü PULLUKÇU, (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Oğuz Reşat SİPAHİ, (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Tansu YAMAZHAN, (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Bilgin ARDA, (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Sercan ULUSOY (Ege Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye)

Turkish Journal of Medical Sciences

8 0

Yıl: 2011 Cilt: 41 Sayı: 3 Sayfa Aralığı: 557 - 564 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007

Öz:

Amaç: Bu çalışmada; 1997-2001 ve 2002- Eylül 2007 dönemlerinde Türkiye’de yapılmış olan yayınlardaki üriner sistem enfeksiyonlarından izole edilen Escherichia coli kökenlerinin direnç durumlarının karşılaştırılması amaçlanmıştır. Yöntem ve gereç: Yayımlanmış olan makaleler üç ulusal veri tabanı (Ulakbim Türk Medikal Literatür veritabanı, http:// www.turkishmedline.com, http://medline.pleksus.com.tr) ve iki uluslar arası (Pubmed and Science Citation Index) veri tabanında taranmıştır. Bulgular: Toplam 53 makalede (1997-2001 döneminden 28 makale, 2002-2007 döneminden 25 makale) 25577 E. coli kökenine ait veriye ulaşılmıştır. Bu kökenlerden 18.106’sı poliklinik hastalarından, 7471’i yatan hastalardan izoleedilmiştir. Poliklinik hastalarından izole edilen kökenler değerlendirildiğinde siprofl oksasin direncinde önemli bir artış görülürken amikasin, gentamisin, netilmisin ve kotrimoksazol direncinde anlamlı bir azalma görülmüştür. Hastanede yatan hastaların verileri analiz edildiğinde amikasin, netilmisin, kotrimoksazol ve amoksisilin/klavulonat direncinde anlamlı azalma izlenirken, nitrofurantoin direncinde anlamlı bir artış gözlenmiştir. Sonuç: Türkiye perspektifi nden bakıldığında verilerimiz aminoglikozit ve üçüncü kuşak sefalosporinler yatan hastalarda iyi seçenekler olabileceğini düşündürmektedir. Komplike olmayan hastaların ampirik tedavisinde fosfomisin/ trometamin, nitrofurantoin ve oral üçüncü kuşak sefalosporinler uygun alternatifl er olabilir. GSBL oranı yatan hastalarda ve poliklinik hastalarında artmaktadır. Toplumda ve hastanede direnç oranlarını sınırlamak için antibiyotik yönetim politikaları ya da kısıtlama programları acilen uygulamaya konulmalıdır

Anahtar Kelime:

Konular: Cerrahi

Türkiye’de idrar kültürlerinden izole edilen Escherichia coli kökenlerinde direnç durumlarının havuz analizi: 1997-2001 ve 2002-2007 dönemlerinin karşılaştırılması

Öz:

Aim: To compare the resistance patterns of Escherichia coli strains reported to be isolated from urine cultures in published medical literature from Turkey in 1997-2001 and 2002-September 2007. Materials and methods: To fi nd the published series, 3 national databases (Ulakbim Turkish Medical Literature database, http://www.turkishmedline.com, http://medline.pleksus.com.tr), and 2 international databases (Pubmed and Science Citation Index (SCI)) were searched. Results: Data for 25,577 E. coli strains were obtained from 53 articles (28 articles from 1997-2001, 25 from 2002-2007). Of these strains 18,106 were isolated from outpatients, whereas 7471 were from inpatients. When the strains isolated from outpatients were evaluated, there was a signifi cant increase in the ciprofl oxacin resistance, whereas there was a signifi cant decrease in amikacin, netilmicin, and co-trimoxazole resistance (P < 0.05). When the data of hospitalized patients were analyzed, there was signifi cant decrease in amikacin, gentamicin, netilmicin, co-trimoxazole, and amoxicillin/clavulanate resistance, whereas a signifi cant increase was observed in nitrofurantoin resistance (P < 0.05). Th e ESBL rate increased in both the inpatients and outpatients (P < 0.05). Conclusion: When looked at from Turkey’s perspective, our data suggest that aminoglycosides and third-generation cephalosporins may be good choices in the treatment of inpatients. Fosfomycin/tromethamine, nitrofurantoin, and oral third-generation cephalosporins may be reasonable alternatives in the empirical treatment of uncomplicated outpatient cases. Policies to constrain resistance in both the community, and hospitals, such as antibiotic stewardship or restriction programs, should be implemented immediately.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TAŞBAKAN M, PULLUKÇU H, SİPAHİ O, YAMAZHAN T, ARDA B, Ulusoy S (2011). A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. , 557 - 564.
Chicago	TAŞBAKAN Meltem IŞIKGÖZ,PULLUKÇU Hüsnü,SİPAHİ Oğuz Reşat,YAMAZHAN Tansu,ARDA BİLGİN,Ulusoy Sercan A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. (2011): 557 - 564.
MLA	TAŞBAKAN Meltem IŞIKGÖZ,PULLUKÇU Hüsnü,SİPAHİ Oğuz Reşat,YAMAZHAN Tansu,ARDA BİLGİN,Ulusoy Sercan A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. , 2011, ss.557 - 564.
AMA	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. . 2011; 557 - 564.
Vancouver	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. . 2011; 557 - 564.
IEEE	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S "A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007." , ss.557 - 564, 2011.
ISNAD	TAŞBAKAN, Meltem IŞIKGÖZ vd. "A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007". (2011), 557-564.

APA	TAŞBAKAN M, PULLUKÇU H, SİPAHİ O, YAMAZHAN T, ARDA B, Ulusoy S (2011). A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. Turkish Journal of Medical Sciences, 41(3), 557 - 564.
Chicago	TAŞBAKAN Meltem IŞIKGÖZ,PULLUKÇU Hüsnü,SİPAHİ Oğuz Reşat,YAMAZHAN Tansu,ARDA BİLGİN,Ulusoy Sercan A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. Turkish Journal of Medical Sciences 41, no.3 (2011): 557 - 564.
MLA	TAŞBAKAN Meltem IŞIKGÖZ,PULLUKÇU Hüsnü,SİPAHİ Oğuz Reşat,YAMAZHAN Tansu,ARDA BİLGİN,Ulusoy Sercan A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. Turkish Journal of Medical Sciences, vol.41, no.3, 2011, ss.557 - 564.
AMA	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. Turkish Journal of Medical Sciences. 2011; 41(3): 557 - 564.
Vancouver	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007. Turkish Journal of Medical Sciences. 2011; 41(3): 557 - 564.
IEEE	TAŞBAKAN M,PULLUKÇU H,SİPAHİ O,YAMAZHAN T,ARDA B,Ulusoy S "A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007." Turkish Journal of Medical Sciences, 41, ss.557 - 564, 2011.
ISNAD	TAŞBAKAN, Meltem IŞIKGÖZ vd. "A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007". Turkish Journal of Medical Sciences 41/3 (2011), 557-564.