Evaluation of autonomic nervous system dysfunction in fibromyalgia

YILDIZ, SERPIL; KAPTANOĞLU, Ece; YAŞAR, MUSTAFA FATİH; Yıldız, Nebil; Sahin, Ozlem

Evaluation of autonomic nervous system dysfunction in fibromyalgia

Özlem ŞAHİN, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Sivas, Türkiye)

Serpil YILDIZ, (Abant İzzet Baysal Üniversitesi, İzzet Baysal Tıp Fakültesi, Nöröloji Anabilim Dalı, Bolu, Türkiye)

Nebil YILDIZ, (Abant İzzet Baysal Üniversitesi, İzzet Baysal Tıp Fakültesi, Nöröloji Anabilim Dalı, Bolu, Türkiye)

Mustafa Fatih YAŞAR, (Abant İzzet Baysal Üniversitesi, İzzet Baysal Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Bolu, Türkiye)

Ece KAPTANOĞLU (Cumhuriyet Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Romatoloji Bilim Dalı, Sivas, Türkiye)

Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi

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Yıl: 2011 Cilt: 57 Sayı: 2 Sayfa Aralığı: 62 - 65 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Evaluation of autonomic nervous system dysfunction in fibromyalgia

Öz:

Amaç: Fibromyaljide (FM) otonom sinir sistemi (OSS) disfonksiyonu hakkındaki çalışmaların farklı sonuçları vardır. Bu çalışmadaki amacımız sempatik deri yanıtı (SDY) cevaplarını kullanarak FM hastalarında sempatik sinir sistemi disfonksiyonunu değerlendirmektir. Gereç ve Yöntem: Çalışmaya 27 fibromyaljili kadın hasta ve 18 sağlıklı gönüllü kadın kontrol alındı. FM hastaları ve sağlıklı kişiler Beck Depresyon Envanteri (BDE), Beck Anksiyete Envanteri (BAE) ve FM için karakteristik olan kronik semptomlar yönünden sorgulandı. Sağ el palmar SDY, median sinirin bilek hizasında elektriksel olarak uyarılması ile elde edildi. Bulgular: FM hastalarında kronik semptomların çoğu yüksek orandaydı. Hastaların ve kontrollerin SDY amplitüd ve latansları arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). BDE ve BAE ortalama değerlerine göre FM hastalarında anksiyete ve depresyon yoktu. Sonuç: Bu çalışmada FM’de OSS disfonksiyonu tesbit edilmedi. SDY sadece sudomotor aktiviteyi gösterdiği için OSS’nin tamamını değerlendirmede yetersiz bir yöntem olabilir. OSS disfonksiyonu FM’nin etyopatogenezinden ziyade FM’de gözlenen bazı kronik semptomlardan, eşlik eden depresyon ve anksiyeteden sorumlu olabilir. FM hastalarının kronik semptom, anksiyete ve depresyon durumları da gözönünde bulundurularak, OSS’nin alt sistemlerini (kardiyovasküler refleks yol, sempatik kolinerjik aktivite gibi) inceleyen çalışmalar ile OSS’nin FM etyopatogenezindeki rolünü belirlemek mümkün olabilir.Türk Fiz Tıp Rehab Derg 2011;57:62-5.

Anahtar Kelime:

Konular: Rehabilitasyon

Fibromyaljide otonom sinir sistemi disfonksiyonunun değerlendirilmesi

Öz:

Objective: There have been conflicting results of studies on autonomic nervous system (ANS) dysfunction in fibromyalgia (FM). The aim of this study was to evaluate the sympathetic nervous system dysfunction via sympathetic skin response (SSR) recordings in patients with FM. Materials and Methods: Twenty-seven female patients with FM and 18 healthy volunteer females as controls were included in the study. All participant were administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) and were questioned about chronic symptoms that are characteristic for FM. Right palmar SSRs were evoked by electrical stimulation of the median nerve at the wrist. Results: The FM patients had higher rates of most of the chronic symptoms of FM. There was no significant difference in SSR latency and amplitude between patients and controls (p>0.05). The patients with FM had no depression and anxiety according to the BDI and BAI mean scores. Conclusion: We did not find ANS dysfunction in the patients with FM. SSR may be an insufficient way of determining the whole ANS dysfunction as it only evaluates the sudomotor component. ANS dysfunction may be responsible for some of the chronic symptoms of FM and accompanying depression and anxiety (not observed in the present study) rather than taking part in the etiopathogenesis. It can be possible to determine the role of ANS in FM etiopathogenesis by studies evaluating the subsystems of ANS (cardiovascular reflex pathway, sympathetic cholinergic activity etc.) in which chronic symptoms of FM, especially anxiety and depression, are also considered.Turk J Phys Med Rehab 2011;57:62-5.

Anahtar Kelime:

Konular: Rehabilitasyon

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Sahin O, YILDIZ S, Yıldız N, YAŞAR M, KAPTANOĞLU E (2011). Evaluation of autonomic nervous system dysfunction in fibromyalgia. , 62 - 65.
Chicago	Sahin Ozlem,YILDIZ SERPIL,Yıldız Nebil,YAŞAR MUSTAFA FATİH,KAPTANOĞLU Ece Evaluation of autonomic nervous system dysfunction in fibromyalgia. (2011): 62 - 65.
MLA	Sahin Ozlem,YILDIZ SERPIL,Yıldız Nebil,YAŞAR MUSTAFA FATİH,KAPTANOĞLU Ece Evaluation of autonomic nervous system dysfunction in fibromyalgia. , 2011, ss.62 - 65.
AMA	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E Evaluation of autonomic nervous system dysfunction in fibromyalgia. . 2011; 62 - 65.
Vancouver	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E Evaluation of autonomic nervous system dysfunction in fibromyalgia. . 2011; 62 - 65.
IEEE	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E "Evaluation of autonomic nervous system dysfunction in fibromyalgia." , ss.62 - 65, 2011.
ISNAD	Sahin, Ozlem vd. "Evaluation of autonomic nervous system dysfunction in fibromyalgia". (2011), 62-65.

APA	Sahin O, YILDIZ S, Yıldız N, YAŞAR M, KAPTANOĞLU E (2011). Evaluation of autonomic nervous system dysfunction in fibromyalgia. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 57(2), 62 - 65.
Chicago	Sahin Ozlem,YILDIZ SERPIL,Yıldız Nebil,YAŞAR MUSTAFA FATİH,KAPTANOĞLU Ece Evaluation of autonomic nervous system dysfunction in fibromyalgia. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 57, no.2 (2011): 62 - 65.
MLA	Sahin Ozlem,YILDIZ SERPIL,Yıldız Nebil,YAŞAR MUSTAFA FATİH,KAPTANOĞLU Ece Evaluation of autonomic nervous system dysfunction in fibromyalgia. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, vol.57, no.2, 2011, ss.62 - 65.
AMA	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E Evaluation of autonomic nervous system dysfunction in fibromyalgia. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2011; 57(2): 62 - 65.
Vancouver	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E Evaluation of autonomic nervous system dysfunction in fibromyalgia. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi. 2011; 57(2): 62 - 65.
IEEE	Sahin O,YILDIZ S,Yıldız N,YAŞAR M,KAPTANOĞLU E "Evaluation of autonomic nervous system dysfunction in fibromyalgia." Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 57, ss.62 - 65, 2011.
ISNAD	Sahin, Ozlem vd. "Evaluation of autonomic nervous system dysfunction in fibromyalgia". Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 57/2 (2011), 62-65.