Morphometric investigations of fresh and fixed rabbit kidney
Yıl: 2011 Cilt: 27 Sayı: 3 Sayfa Aralığı: 149 - 154 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Morphometric investigations of fresh and fixed rabbit kidney
Öz: Amaç: Bu çalışmada formaldehit tespitinin böbrek morfo-metrisine etkisi ile böbreği oluşturan yapıların hacim ölçümlerinin ve ilgili yapıların böbrek içerisindeki hacimsel oranlarının Cavalieri prensibi kullanarak değerlendirilmesi amaçlandı.Gereç ve Yöntem: Çalışmada 9 adet sağlıklı erkek Yeni Zelanda beyaz tavşanına ait böbrekler kullanıldı. Taze böbreklere ait ağırlık verileri elde edildikten sonra craniocaudal uzunluk, dorsoventral ve mediolateral çap ölçümleri dijital kumpas yardımı ile yapıldı. Her bir böbreğe ait hacim ölçümleri Arşimed prensibi ile gerçekleştirildi. Bu işlemlerden sonra taze böbrekler %10 formol içeren kaplarda 15 gün süre ile tespit edildi. Tespit edilen böbrekler üzerinde taze böbreklerde yapılan ölçüm işlemleri tekrarlandı ve böbreği oluşturan yapıların (korteks, medulla ve pelvis re-nalis) hacimleri Cavalieri prensibi ile hesaplandı.Bulgular: Taze (15.8±0.26 mm) ve tespit edilmiş (14.8±0.32 mm) sağ böbreklere ait dorsoventral çap değerleri arasında istatistiki olarak önemli fark tespit edildi (p<0.05). Sol ve sağ böbreğe ait rölatif organ ağırlıkları sırası ile %0.38±0.02 ve %0.38±0.01 olarak belirlendi. Formol ile tespit sonrası sol ve sağ böbrek ağırlıklarının sırası ile %7.33 ve %7.56 oranında arttığı görüldü. Tespit sonrası hacim değerlerinde ağırlık artışına paralel olarak sol böbrekte %7.13 (p<0.05), sağ böbrekte ise %3.34 (p>0.05) oranında artış olduğu tespit edildi.Öneri: Taze ve formol ile tespit edilmiş böbreklere ait elde edilen morfometrik verilerin gelecekte invaziv ve noninva-ziv metotların kullanıldığı böbrek hastalıkları üzerinde yapılacak çalışmalara katkı sağlayacağı düşünüldü.
Anahtar Kelime: Konular:
Taze ve tespit edilmiş tavşan böbreği üzerinde morfometrik araştırmalar.
Öz: Aim: The aim of this study was to investigate the effect of formalin fixation on the morphometry of kidneys, and to assess the volume and fractions of its constituents using the Cavalieri principle. Materials and Methods: In this study, kidneys of nine healthy male White New Zealand rabbits were used. After weighing the kidneys, craniocaudal length, and mediolateral and dorsoventral diameters of fresh kidneys were measured with digital calipers, and the volume of each kidney was estimated using Archimedes' principle. The fresh kidneys were kept in a container of 10% formalin solution for 15 days. The Cavalieri principle was utilized for the determination of volume and the volume fraction of renal constituents. Results: The differences in the dorsoventral diameter of fresh (15.8±0.26 mm) and fixed (14.8±0.32 mm) right kidneys were found to be statistically significant (p<0.05). The relative organ weights were determined to be 0.38±0.02% and 0.38±0.01% for the left and right kidneys, respectively. After formalin fixation, the weights of the left and right kidney increased by 7.33% and 7.56% respectively, and an increase in volume was determined between fresh and fixed left (7.13%, p<0.05) and right kidneys (3.34%, p>0.05). Conclusion: It is believed that obtained morphometric data will contribute to studies involving the investigation of kidney diseases using invasive and non-invasive methods.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | BOLAT D, BAHAR S, Selçuk M, TIPIRDAMAZ S (2011). Morphometric investigations of fresh and fixed rabbit kidney. , 149 - 154. |
| Chicago | BOLAT DURMUŞ,BAHAR Sadullah,Selçuk Muhammet Lütfi,TIPIRDAMAZ Sadettin Morphometric investigations of fresh and fixed rabbit kidney. (2011): 149 - 154. |
| MLA | BOLAT DURMUŞ,BAHAR Sadullah,Selçuk Muhammet Lütfi,TIPIRDAMAZ Sadettin Morphometric investigations of fresh and fixed rabbit kidney. , 2011, ss.149 - 154. |
| AMA | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S Morphometric investigations of fresh and fixed rabbit kidney. . 2011; 149 - 154. |
| Vancouver | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S Morphometric investigations of fresh and fixed rabbit kidney. . 2011; 149 - 154. |
| IEEE | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S "Morphometric investigations of fresh and fixed rabbit kidney." , ss.149 - 154, 2011. |
| ISNAD | BOLAT, DURMUŞ vd. "Morphometric investigations of fresh and fixed rabbit kidney". (2011), 149-154. |
| APA | BOLAT D, BAHAR S, Selçuk M, TIPIRDAMAZ S (2011). Morphometric investigations of fresh and fixed rabbit kidney. Eurasian Journal of Veterinary Sciences, 27(3), 149 - 154. |
| Chicago | BOLAT DURMUŞ,BAHAR Sadullah,Selçuk Muhammet Lütfi,TIPIRDAMAZ Sadettin Morphometric investigations of fresh and fixed rabbit kidney. Eurasian Journal of Veterinary Sciences 27, no.3 (2011): 149 - 154. |
| MLA | BOLAT DURMUŞ,BAHAR Sadullah,Selçuk Muhammet Lütfi,TIPIRDAMAZ Sadettin Morphometric investigations of fresh and fixed rabbit kidney. Eurasian Journal of Veterinary Sciences, vol.27, no.3, 2011, ss.149 - 154. |
| AMA | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S Morphometric investigations of fresh and fixed rabbit kidney. Eurasian Journal of Veterinary Sciences. 2011; 27(3): 149 - 154. |
| Vancouver | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S Morphometric investigations of fresh and fixed rabbit kidney. Eurasian Journal of Veterinary Sciences. 2011; 27(3): 149 - 154. |
| IEEE | BOLAT D,BAHAR S,Selçuk M,TIPIRDAMAZ S "Morphometric investigations of fresh and fixed rabbit kidney." Eurasian Journal of Veterinary Sciences, 27, ss.149 - 154, 2011. |
| ISNAD | BOLAT, DURMUŞ vd. "Morphometric investigations of fresh and fixed rabbit kidney". Eurasian Journal of Veterinary Sciences 27/3 (2011), 149-154. |
