Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings

ÇAKMAK, Fatma Nur; DİBEK MISIRLIOĞLU, Emine; BADEMCİ, Gülşah; ALİEFENDİOĞLU, Didem; KÖSE, Gülşen; BAYDAR, Zekiye

Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings

Emine DİBEK MISIRLIOĞLU, (Kırıkkale Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Kırıkkale, Türkiye)

Didem ALİEFENDİOĞLU, (Kırıkkale Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Kırıkkale, Türkiye)

Gülşah BADEMCİ, (Kırıkkale Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Kırıkkale, Türkiye)

Zekiye BAYDAR, (Ankara Dışkapı Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Gülşen KÖSE, (Ankara Dışkapı Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Fatma Nur ÇAKMAK (Ankara Dışkapı Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Journal of Neurological Sciences (Turkish)

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Yıl: 2009 Cilt: 26 Sayı: 1 Sayfa Aralığı: 18 - 25 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings

Öz:

Bu çalışmada; K vitamini eksikliğine bağlı intrakraniyal kanaması olan 25 infantın klinik, radyolojik bulguları ve risk faktörleri geriye dönük olarak değerlendirildi.25 olgunun 2 (%8)'si klasik tip ve 23'ü geç başlangıçlı tipte idi. 18 (%72)'i erkek ve 7 (%28)'si kız idi. Olguların 24 (%96)'ü sadece anne sütü ile beslenmekteydi. Olguların 18'ine doğumdan sonra K vitamini uygulanmıştı. En fazla görülen semptom kusma (%44) ve konvülsiyon (%40) idi. En fazla saptanan muayene bulgusu fontanel bombeliği (%40) ve solukluk (%40) idi. Onbir (%44) hastada intrakraniyal kanama birden fazla bölgede vardı ve kanama en fazla (%68) intraparankimal alana olmuştu. 12 olgu izleminde normal mental-motor gelişim gösterirken, mortalite oranı %8 bulundu.İntrakraniyal kanama özellikle geç tipin bulgusu olup en fazla intraparankimal alanda olmaktadır. Anne sütü ile beslenen bebeklerde doğumdan sonra K vitaminin yapılmamış olması en önemli risk faktörüdür.

Anahtar Kelime:

Konular: Nörolojik Bilimler

İnfantlarda K vitamini eksikliğine bağlı intrakraniyal kanama: Klinik ve radyolojik bulgular

Öz:

This retrospective study presents clinical and radiological findings and outcomes of 25 infants with intracranial hemorrhage due to vitamin K deficiency and evaluates the risk factors.Two of the infants (8%) were classical type and the others were late onset. Of the patients, 18 (72%) were male and 7 (28%) were female. Twenty four infants (96%) were being fed exclusively on breast milk. Eighteen of them (72%) had not received vitamin K prophylaxis at birth. The most disabling clinical symptoms were vomiting (44%) and convulsions (40%). The most common presentations were bulging fontanel (40%) and paleness (40%). Eleven patients (44%) showed intracranial hemorrhages at more than one site. Intraparenchymal hemorrhage was the commonest (68%) type of hemorrhage. Twelve of cases (57%) were developmentally normal. Mortality rate was 8%.Late type is frequently associated with intracranial hemorrhage particularly intraparenchymal. Lack of administration of vitamin K at birth to breastfeed babies is the most important risk factor for intracranial hemorrhage.

Anahtar Kelime:

Konular: Nörolojik Bilimler

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	DİBEK MISIRLIOĞLU E, ALİEFENDİOĞLU D, BADEMCİ G, BAYDAR Z, KÖSE G, ÇAKMAK F (2009). Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. , 18 - 25.
Chicago	DİBEK MISIRLIOĞLU Emine,ALİEFENDİOĞLU Didem,BADEMCİ Gülşah,BAYDAR Zekiye,KÖSE Gülşen,ÇAKMAK Fatma Nur Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. (2009): 18 - 25.
MLA	DİBEK MISIRLIOĞLU Emine,ALİEFENDİOĞLU Didem,BADEMCİ Gülşah,BAYDAR Zekiye,KÖSE Gülşen,ÇAKMAK Fatma Nur Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. , 2009, ss.18 - 25.
AMA	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. . 2009; 18 - 25.
Vancouver	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. . 2009; 18 - 25.
IEEE	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F "Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings." , ss.18 - 25, 2009.
ISNAD	DİBEK MISIRLIOĞLU, Emine vd. "Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings". (2009), 18-25.

APA	DİBEK MISIRLIOĞLU E, ALİEFENDİOĞLU D, BADEMCİ G, BAYDAR Z, KÖSE G, ÇAKMAK F (2009). Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish), 26(1), 18 - 25.
Chicago	DİBEK MISIRLIOĞLU Emine,ALİEFENDİOĞLU Didem,BADEMCİ Gülşah,BAYDAR Zekiye,KÖSE Gülşen,ÇAKMAK Fatma Nur Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish) 26, no.1 (2009): 18 - 25.
MLA	DİBEK MISIRLIOĞLU Emine,ALİEFENDİOĞLU Didem,BADEMCİ Gülşah,BAYDAR Zekiye,KÖSE Gülşen,ÇAKMAK Fatma Nur Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish), vol.26, no.1, 2009, ss.18 - 25.
AMA	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish). 2009; 26(1): 18 - 25.
Vancouver	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish). 2009; 26(1): 18 - 25.
IEEE	DİBEK MISIRLIOĞLU E,ALİEFENDİOĞLU D,BADEMCİ G,BAYDAR Z,KÖSE G,ÇAKMAK F "Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings." Journal of Neurological Sciences (Turkish), 26, ss.18 - 25, 2009.
ISNAD	DİBEK MISIRLIOĞLU, Emine vd. "Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings". Journal of Neurological Sciences (Turkish) 26/1 (2009), 18-25.