Yıl: 2012 Cilt: 11 Sayı: 4 Sayfa Aralığı: 208 - 211 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Silent cerebral ischemia and infarct prevelance in chronic renal failure patients

Öz:
Amaç: Serebrovasküler hastalıklar tüm dünyada mortalite ve morbiditenin en önemli sebebidir. İskemik infarktlar, serebrovasküler hastalıklar içerisinde en sık görülen ve en çok ölüme neden olan grubu oluşturur. Sessiz serebral iskemili hastalarda, iskemik infarkt insidansı normal populasyona göre 10 kat daha fazladır. Serebral infarkt geliştikten sonra uygulanan tedavi modaliteleri yeterli olmamaktadır. Bu sebeble risk faktörlerinin tespiti, primer ve sekonder profilaksi, erken tanı, tedavi ve rehabilitasyon için yapılan çalışmalar önem kazanmaktadır. Serebrovasküler hastalıklar diyaliz hastalarında da ölümün major nedenlerinden biridir. Kronik böbrek yetmezliği (KBY) ve diyaliz tedavisinin serebral iskemi ve infarkt gelişimi üzerine etkisi henüz açıklığa kavuşturulamamıştır. Biz bu çalışmada, hemodiyaliz ve periton diyaliz tedavisi alan KBY hastalarında sessiz serebral iskemi ve infarkt prevalansını manyetik resonans görüntüleme (MRG) ile araştırdık. Gereç ve Yöntemler: Otuz hemodiyaliz ve 40 periton diyaliz hastası vaka grubu olarak, acil servise başvuran nörolojik şikayetleri olamayan 50 hasta ise kontrol grubu olarak çalışmaya alınmıştır. Bulgular: Vaka ve kontrol grupları benzer demografik özellikler ve risk faktörleri taşımalarına rağmen, KBY’ li hastalarda kontrol grubuna kıyasla sessiz serebral iskemi ve infarkt prevalansının anlamlı şekilde arttığı gözlenmiştir. Sonuç: KBY’nin serebral iskemi ve infarkt gelişimi üzerine istatistiksel olarak anlamlı etkisinin (MRG ile ortaya konan) olduğu belirlenmiştir. Elde edilen bu sonuçlar, KBY’ nin iskemik strok gelişiminde önemli bir risk faktörü olduğunu, daha geniş klinik ve deneysel çalışmalarla bu konunun araştırılması gerektiğini ortaya koymuştur. (JAEM 2012; 11: 208-11)
Anahtar Kelime:

Konular: Acil Tıp

Kronik böbrek yetmezlikli hastalarda sessiz serebral iskemi ve infarkt prevalansı

Öz:
Objective: Cerebrovascular diseases are the most common causes of morbidity and mortality. The ischemic type is the most common and most fatal o among the all cerebrovasculer diseases. In patients having silent cerebral ischemia the incidence of ischemic infarction is ten times greater than in the normal population. The treatment modalities are not efficient after the cerebral infarct has occurred. For this reason academic studies are gaining importance for the determination of risk factors, primary and secondary prophylaxis, early diagnosis, treatment and rehabilitation. Cerebrovascular diseases are also the most common major causes of death in hemodialysis patients. The effect of dialysis treatment and chronic renal failure disease on the development of cerebral ischemia and infarct has not been explained, In this study we analyzed the prevalence of silent cerebral ischemia and infarct in the cronic renal failure patients having hemodialysis and peritoneal dialysis treatment, using magnetic resonance imaging. Material and Methods: The study included 30 patients with hemodialysis, 40 patients with peritoneal dialysis and control group of 50 patients admitted to emergency department due to complaints other than neurological ones. Results: Although the case and control groups having similar demographical properties and risk factors, the prevalence of silent cerebral ischemia and infarct is determined as significantly increased in the chronic renal failure patient group. Conclusion: It is determined by MR that chronic renal failure has significant effects on developing cerebral ischemia and infarct. These findings showed us chronic renal failiure is an important risk factor for developing cerebral ischemic stroke. Additional clinical and experimental studies are needed on this subject. (JAEM 2012; 11: 208-11)
Anahtar Kelime:

Konular: Acil Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA KEBAPÇIOĞLU A, BAKOĞLU E, KAFALI M, GİRİŞGİN A, KOYUNCU F, BİRCAN M, GÜL M, Kocak S (2012). Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. , 208 - 211.
Chicago KEBAPÇIOĞLU Ali Sedat,BAKOĞLU Ertan,KAFALI Mehmet Ertuğrul,GİRİŞGİN ABDULLAH SADIK,KOYUNCU Feridun,BİRCAN Metin,GÜL MEHMET,Kocak Sedat Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. (2012): 208 - 211.
MLA KEBAPÇIOĞLU Ali Sedat,BAKOĞLU Ertan,KAFALI Mehmet Ertuğrul,GİRİŞGİN ABDULLAH SADIK,KOYUNCU Feridun,BİRCAN Metin,GÜL MEHMET,Kocak Sedat Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. , 2012, ss.208 - 211.
AMA KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. . 2012; 208 - 211.
Vancouver KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. . 2012; 208 - 211.
IEEE KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S "Silent cerebral ischemia and infarct prevelance in chronic renal failure patients." , ss.208 - 211, 2012.
ISNAD KEBAPÇIOĞLU, Ali Sedat vd. "Silent cerebral ischemia and infarct prevelance in chronic renal failure patients". (2012), 208-211.
APA KEBAPÇIOĞLU A, BAKOĞLU E, KAFALI M, GİRİŞGİN A, KOYUNCU F, BİRCAN M, GÜL M, Kocak S (2012). Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. Akademik Acil Tıp Dergisi, 11(4), 208 - 211.
Chicago KEBAPÇIOĞLU Ali Sedat,BAKOĞLU Ertan,KAFALI Mehmet Ertuğrul,GİRİŞGİN ABDULLAH SADIK,KOYUNCU Feridun,BİRCAN Metin,GÜL MEHMET,Kocak Sedat Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. Akademik Acil Tıp Dergisi 11, no.4 (2012): 208 - 211.
MLA KEBAPÇIOĞLU Ali Sedat,BAKOĞLU Ertan,KAFALI Mehmet Ertuğrul,GİRİŞGİN ABDULLAH SADIK,KOYUNCU Feridun,BİRCAN Metin,GÜL MEHMET,Kocak Sedat Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. Akademik Acil Tıp Dergisi, vol.11, no.4, 2012, ss.208 - 211.
AMA KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. Akademik Acil Tıp Dergisi. 2012; 11(4): 208 - 211.
Vancouver KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S Silent cerebral ischemia and infarct prevelance in chronic renal failure patients. Akademik Acil Tıp Dergisi. 2012; 11(4): 208 - 211.
IEEE KEBAPÇIOĞLU A,BAKOĞLU E,KAFALI M,GİRİŞGİN A,KOYUNCU F,BİRCAN M,GÜL M,Kocak S "Silent cerebral ischemia and infarct prevelance in chronic renal failure patients." Akademik Acil Tıp Dergisi, 11, ss.208 - 211, 2012.
ISNAD KEBAPÇIOĞLU, Ali Sedat vd. "Silent cerebral ischemia and infarct prevelance in chronic renal failure patients". Akademik Acil Tıp Dergisi 11/4 (2012), 208-211.