The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats

Fikriye POLAT, (Kocaeli Üniversitesi, Kocaeli, Türkiye)
Egemen DERE, (Uludağ Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Bursa, Türkiye)
Eylem GÜL, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, İstanbul, Türkiye)
İzzet YELKUVAN, (Cumhuriyet Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Sivas, Türkiye)
Öztürk ÖZDEMİR, (Çanakkale Onsekiz Mart Üniversitesi, Çanakkale, Türkiye)
Günsel BİNGÖL (Boş)
Turkish Journal of Biology
9 0
Yıl: 2013 Cilt: 37 Sayı: 1 Sayfa Aralığı: 33 - 38 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats

Öz:
This study examined the effects of separate and combined applications of 3-methylcholanthrene, a polycyclic aromatic hydrocarbon and potent carcinogenic agent, and butylated hydroxytoluene, the antioxidant food additive, on the glycogen levels of liver, muscle, testis, and tumor tissues in rats. Adult male Wistar albino rats weighing 100 110 g at 8 weeks of age were used in this study. This study consisted of a control group (n = 9) and 3 different experiment groups in which rats were chronically treated with 3-methylcholanthrene (n = 9) or butylated hydroxytoluene (n = 11) or a combination of these agents (n = 14). Rats were intraperitoneally injected with a 200 mg kg −1 dose of butylated hydroxytoluene and a 40 mg kg1 dose of 3-methylcholanthrene. At the end of the 26-week experimental period, tissues of rats killed via cervical dislocation were placed in 10% trichloroacetic acid for glycogen determination. Our results showed that the administration of 3-methylcholanthrene, butylated hydroxytoluene, and 3-methylcholanthrene + butylated hydroxytoluene caused statistically significant changes in the glycogen levels of liver, muscle, and testis tissues, and glycogen was stored in tumor tissue.
Anahtar Kelime: rats 3-methylcholanthrene carcinogens glycogen butylated hydroxyanisole food additives neoplasms polycyclic hydrocarbons

Konular: Biyoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Polat F, DERE E, GÜL E, Yelkuvan İ, ÖZDEMİR Ö, Bingöl G (2013). The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. , 33 - 38.
Chicago Polat Fikriye,DERE EGEMEN,GÜL Eylem,Yelkuvan İzzet,ÖZDEMİR Öztürk,Bingöl Günsel The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. (2013): 33 - 38.
MLA Polat Fikriye,DERE EGEMEN,GÜL Eylem,Yelkuvan İzzet,ÖZDEMİR Öztürk,Bingöl Günsel The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. , 2013, ss.33 - 38.
AMA Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. . 2013; 33 - 38.
Vancouver Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. . 2013; 33 - 38.
IEEE Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G "The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats." , ss.33 - 38, 2013.
ISNAD Polat, Fikriye vd. "The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats". (2013), 33-38.
APA Polat F, DERE E, GÜL E, Yelkuvan İ, ÖZDEMİR Ö, Bingöl G (2013). The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. Turkish Journal of Biology, 37(1), 33 - 38.
Chicago Polat Fikriye,DERE EGEMEN,GÜL Eylem,Yelkuvan İzzet,ÖZDEMİR Öztürk,Bingöl Günsel The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. Turkish Journal of Biology 37, no.1 (2013): 33 - 38.
MLA Polat Fikriye,DERE EGEMEN,GÜL Eylem,Yelkuvan İzzet,ÖZDEMİR Öztürk,Bingöl Günsel The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. Turkish Journal of Biology, vol.37, no.1, 2013, ss.33 - 38.
AMA Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. Turkish Journal of Biology. 2013; 37(1): 33 - 38.
Vancouver Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats. Turkish Journal of Biology. 2013; 37(1): 33 - 38.
IEEE Polat F,DERE E,GÜL E,Yelkuvan İ,ÖZDEMİR Ö,Bingöl G "The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats." Turkish Journal of Biology, 37, ss.33 - 38, 2013.
ISNAD Polat, Fikriye vd. "The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats". Turkish Journal of Biology 37/1 (2013), 33-38.
Sayfa Oluşturulma Tarihi
17-04-2024 0:44

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