Relation between aortic stiffness and extension of coronary artery disease

BOSTAN, Mehmet; çiçek, yüksel gülen; Bozkurt, Engin; ŞATIROĞLU, Ömer; ÇETİN, Mustafa; Bayar, Nermin

Relation between aortic stiffness and extension of coronary artery disease

Ömer ŞATIROĞLU, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Mehmet BOSTAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Nermin BAYAR, (Sağlık Bakanlığı, Rize Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Rize, Türkiye)

Yüksel ÇİÇEK, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Mustafa ÇETİN, (Sağlık Bakanlığı, Rize Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Rize, Türkiye)

Engin BOZKURT (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Turkish Journal of Medical Sciences

0 1

Yıl: 2012 Cilt: 42 Sayı: 3 Sayfa Aralığı: 417 - 424 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Relation between aortic stiffness and extension of coronary artery disease

Öz:

Amaç: Bu araştırmada, koroner arter hastalığının yaygınlığı ve ciddiyeti ile aortun elastikiyet özellikleri arasındaki ilişki araştırıldı. Yöntem ve gereç: Çalışmaya, koroner arter hastalığı (KAH) şüphesiyle elektif koroner anjiyografi yapılan ardışık yüz hasta alındı. Bunlardan KAH tespit edilen, yaş ortalamaları 62,1 ± 10,3 yıl olan 47 erkek, 16 kadın toplam 63 hasta grup 1 olarak alındı. Koroner arterleri normal ve yaş ortalamaları 51,4 ± 10,8 yıl olan 20 erkek, 17 kadın toplam 37 olgu grup 2 olarak alındı. Koroner anjiyografi sonrası tüm hastalara ekokardiyografi yapılarak aortun elastik özellikleri (aortik distensibilite ve stifness index) ölçüldü. Hastaların yaş, cinsiyet ve ateroskleroz risk faktörleri sorgulandı. Koroner anjiyografi de % 50den fazla darlık olması ciddi koroner arter hastalığı olarak kabul edildi. Koroner arter hastalığının yaygınlığı gensini skoru ile belirlendi. Bulgular: Grup 1 deki hastaların yaş ortalamaları (62,1 ± 10,3 yıl) ve erkek cinsiyet oranı, grup 2den (51,4 ± 10,8) daha fazla bulundu (sırasıyla P < 0.001, P = 0.035). Grup 1in aortik stifnes ortalaması grup 2ye göre anlamlı derecede artarken (sırasıyla, 8,9 ± 5,1 mm, 6,1 ± 4,6 mm, P = 0.001). aortik distensibilite ortalaması ise anlamlı derecede azalmış bulundu (sırasıyla, 23,4 ± 16,5 mm, 42,4 ± 27,1 mm, P < 0.001). İleri yaş, koroner arter hastalığı risk faktörleri ve koroner arter hastalığının yaygınlığı ile korele olarak aortik stifnes indeks artmakta, distensibilite azalmaktadır. Sonuç: KAHın yaygınlığı ve tutulan koroner damar sayısı ile orantılı olarak aortik stifnesi artmakta, distensibilite ise azalmaktadır.

Anahtar Kelime:

Konular: Cerrahi

Koroner arter hastalığının yaygınlığı ile aortik stiffnes ilişkisi

Öz:

Aim: To investigate the relation between aortic stiffness and the extension/severity of coronary artery disease (CAD). Materials and methods: A consecutive 100 patients with suspicion of CAD who underwent elective coronary angiography were enrolled in this study. Of those patients determined as having CAD, 63 were classifi ed as Group I (mean age: 62.1 ± 10.3 years; 47 male and 16 female). Group II included 37 patients with normal coronary arteries (mean age: 51.4 ± 10.8 years; 20 male and 17 female). Aortic flexibility (aortic distensibility and stiffness index) was evaluated by echocardiography aft er coronary angiography in all of the patients. Patient data were gathered in relation to age, sex, and atherosclerotic risk factors. Stenosis above 50% was accepted as severe CAD. The extension of coronary artery disease was determined using the Gensini score. Results: The mean age (62.1 ± 10.3 and 51.4 ± 10.8, respectively) and the male/female rate in Group I were higher than in Group II (P < 0.001 and P = 0.035, respectively). The mean aortic stiffness in Group I was significantly increased compared to Group II (8.9 ± 5.1 mm and 6.1 ± 4.6 mm, respectively; P = 0.001), whereas the mean aortic distensibility in Group I was signifi cantly lower than in Group II (23.4 ± 16.5 mm and 42.4 ± 27.1 mm, respectively; P < 0.001). The aortic stiffness index increased and distensibility decreased in correlation with age, coronary artery risk factors, and extension of CAD. Conclusion: The aortic stiffness index increased and distensibility decreased in correlation with CAD extension and the number of affected coronary arteries.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ŞATIROĞLU Ö, BOSTAN M, Bayar N, çiçek y, ÇETİN M, Bozkurt E (2012). Relation between aortic stiffness and extension of coronary artery disease. , 417 - 424.
Chicago	ŞATIROĞLU Ömer,BOSTAN Mehmet,Bayar Nermin,çiçek yüksel gülen,ÇETİN Mustafa,Bozkurt Engin Relation between aortic stiffness and extension of coronary artery disease. (2012): 417 - 424.
MLA	ŞATIROĞLU Ömer,BOSTAN Mehmet,Bayar Nermin,çiçek yüksel gülen,ÇETİN Mustafa,Bozkurt Engin Relation between aortic stiffness and extension of coronary artery disease. , 2012, ss.417 - 424.
AMA	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E Relation between aortic stiffness and extension of coronary artery disease. . 2012; 417 - 424.
Vancouver	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E Relation between aortic stiffness and extension of coronary artery disease. . 2012; 417 - 424.
IEEE	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E "Relation between aortic stiffness and extension of coronary artery disease." , ss.417 - 424, 2012.
ISNAD	ŞATIROĞLU, Ömer vd. "Relation between aortic stiffness and extension of coronary artery disease". (2012), 417-424.

APA	ŞATIROĞLU Ö, BOSTAN M, Bayar N, çiçek y, ÇETİN M, Bozkurt E (2012). Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences, 42(3), 417 - 424.
Chicago	ŞATIROĞLU Ömer,BOSTAN Mehmet,Bayar Nermin,çiçek yüksel gülen,ÇETİN Mustafa,Bozkurt Engin Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences 42, no.3 (2012): 417 - 424.
MLA	ŞATIROĞLU Ömer,BOSTAN Mehmet,Bayar Nermin,çiçek yüksel gülen,ÇETİN Mustafa,Bozkurt Engin Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences, vol.42, no.3, 2012, ss.417 - 424.
AMA	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences. 2012; 42(3): 417 - 424.
Vancouver	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences. 2012; 42(3): 417 - 424.
IEEE	ŞATIROĞLU Ö,BOSTAN M,Bayar N,çiçek y,ÇETİN M,Bozkurt E "Relation between aortic stiffness and extension of coronary artery disease." Turkish Journal of Medical Sciences, 42, ss.417 - 424, 2012.
ISNAD	ŞATIROĞLU, Ömer vd. "Relation between aortic stiffness and extension of coronary artery disease". Turkish Journal of Medical Sciences 42/3 (2012), 417-424.