Early oxidative status in adult patients with isolated traumatic brain injury

Özgür SÖĞÜT, (Harran Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
Halil KAYA, (Harran Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
Mehmet Tahir GÖKDEMİR, (Harran Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
Leyla SOLDUK, (Harran Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
Mehmet Akif DOKUZOĞLU, (Harran Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
Mustafa Burak SAYHAN, (Trakya Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Edirne, Türkiye)
Atılhan KAYA, (Harran Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Şanlıurfa, Türkiye)
ABDÜRRAHİM KOÇYİĞİT (Harran Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Şanlıurfa, Türkiye)
Turkish Journal of Medical Sciences
0 1
Yıl: 2012 Cilt: 42 Sayı: 6 Sayfa Aralığı: 1010 - 1019 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Early oxidative status in adult patients with isolated traumatic brain injury

Öz:
Aim: To investigate oxidative and antioxidative status, as well as the Glasgow Coma Scale (GCS) and Revised Trauma Score (RTS), reflecting injury severity and neurological outcome during the early posttraumatic period in patients with isolated traumatic brain injury (TBI). Materials and methods: Fift y-one adult patients with TBI and 45 eligible healthy volunteers as control subjects were enrolled. Plasma total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) were calculated as biomarkers of early oxidative changes in serum using a novel automated method. Results: TOS levels and OSI values were significantly higher in nonsurvivors compared with those in survivors. However, there was no significant difference in TAS levels between survivors and nonsurvivors. GCS and RTS showed negative correlations with TOS levels, but neither was significantly related to OSI levels. Furthermore, GCS scores were negatively correlated with TAS levels, whereas RTS scores were not signifi cantly related to TAS levels. Conclusion: Patients with isolated TBI are exposed to potent oxidative stress. TOS, as an early oxidative stress biomarker, might reflect the severity of cerebral insult in those patients.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA SÖĞÜT O, Kaya H, Gökdemir M, SOLDUK L, DOKUZOĞLU M, Sayhan M, KAYA A, KOÇYİĞİT A (2012). Early oxidative status in adult patients with isolated traumatic brain injury. , 1010 - 1019.
Chicago SÖĞÜT Ozgur,Kaya Halil,Gökdemir Mehmet Tahir,SOLDUK Leyla,DOKUZOĞLU Mehmet Akif,Sayhan Mustafa Burak,KAYA Atılhan,KOÇYİĞİT ABDÜRRAHİM Early oxidative status in adult patients with isolated traumatic brain injury. (2012): 1010 - 1019.
MLA SÖĞÜT Ozgur,Kaya Halil,Gökdemir Mehmet Tahir,SOLDUK Leyla,DOKUZOĞLU Mehmet Akif,Sayhan Mustafa Burak,KAYA Atılhan,KOÇYİĞİT ABDÜRRAHİM Early oxidative status in adult patients with isolated traumatic brain injury. , 2012, ss.1010 - 1019.
AMA SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A Early oxidative status in adult patients with isolated traumatic brain injury. . 2012; 1010 - 1019.
Vancouver SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A Early oxidative status in adult patients with isolated traumatic brain injury. . 2012; 1010 - 1019.
IEEE SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A "Early oxidative status in adult patients with isolated traumatic brain injury." , ss.1010 - 1019, 2012.
ISNAD SÖĞÜT, Ozgur vd. "Early oxidative status in adult patients with isolated traumatic brain injury". (2012), 1010-1019.
APA SÖĞÜT O, Kaya H, Gökdemir M, SOLDUK L, DOKUZOĞLU M, Sayhan M, KAYA A, KOÇYİĞİT A (2012). Early oxidative status in adult patients with isolated traumatic brain injury. Turkish Journal of Medical Sciences, 42(6), 1010 - 1019.
Chicago SÖĞÜT Ozgur,Kaya Halil,Gökdemir Mehmet Tahir,SOLDUK Leyla,DOKUZOĞLU Mehmet Akif,Sayhan Mustafa Burak,KAYA Atılhan,KOÇYİĞİT ABDÜRRAHİM Early oxidative status in adult patients with isolated traumatic brain injury. Turkish Journal of Medical Sciences 42, no.6 (2012): 1010 - 1019.
MLA SÖĞÜT Ozgur,Kaya Halil,Gökdemir Mehmet Tahir,SOLDUK Leyla,DOKUZOĞLU Mehmet Akif,Sayhan Mustafa Burak,KAYA Atılhan,KOÇYİĞİT ABDÜRRAHİM Early oxidative status in adult patients with isolated traumatic brain injury. Turkish Journal of Medical Sciences, vol.42, no.6, 2012, ss.1010 - 1019.
AMA SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A Early oxidative status in adult patients with isolated traumatic brain injury. Turkish Journal of Medical Sciences. 2012; 42(6): 1010 - 1019.
Vancouver SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A Early oxidative status in adult patients with isolated traumatic brain injury. Turkish Journal of Medical Sciences. 2012; 42(6): 1010 - 1019.
IEEE SÖĞÜT O,Kaya H,Gökdemir M,SOLDUK L,DOKUZOĞLU M,Sayhan M,KAYA A,KOÇYİĞİT A "Early oxidative status in adult patients with isolated traumatic brain injury." Turkish Journal of Medical Sciences, 42, ss.1010 - 1019, 2012.
ISNAD SÖĞÜT, Ozgur vd. "Early oxidative status in adult patients with isolated traumatic brain injury". Turkish Journal of Medical Sciences 42/6 (2012), 1010-1019.
Sayfa Oluşturulma Tarihi
17-04-2024 0:52

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