The value of serum BNP for the diagnosis of intracranial injury in head trauma

Sayhan, Mustafa Burak; AKDUR, Gökhan; YEMENİCİ, Serap; kavalci, cemil

The value of serum BNP for the diagnosis of intracranial injury in head trauma

Cemil KAVALCI, (Sağlık Bakanlığı, Ankara Numune Eğitim ve Araştırma Hastanesi, Acil Tıp Kliniği, Ankara, Türkiye)

Gökhan AKDUR, (Trakya Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Edirne, Türkiye)

Serap YEMENİCİ, (Trakya Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Edirne, Türkiye)

Mustafa Burak SAYHAN (Trakya Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Edirne, Türkiye)

Türkiye Acil Tıp Dergisi

6 0

Yıl: 2012 Cilt: 12 Sayı: 3 Sayfa Aralığı: 112 - 116 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The value of serum BNP for the diagnosis of intracranial injury in head trauma

Öz:

Amaç: Travmalar 1-44 yaş arası insanlarda ölümün en sık nedenidir. Bilgisayarlı Beyin Tomografisi bu hastalarda tanı için kullanılır. Brain Natriüretik Peptit (BNP) serebral ventriküllerden izole edilmiştir. Bu çalışmada acile kafa travması ile başvuran hastalarda kafa içi yaralanmayı belirlemede yatak başı serum BNP seviyelerinin yeri olup/olmadığının araştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışma Trakya Üniversitesi Tıp Fakültesi Acil Servisinde prospektif olarak yapılmıştır. Kafa travması nedeniyle acile gelen 100 hasta çalışmaya alınmıştır. İkili grupları karşılaştırmada Mann-Whitney U, çoklu grupları karşılaştırmada Kruskal-Wallis testi kullanılmıştır. p<0.05 değeri istatistiksel olarak önemli kabul edilmiştir. Bulgular: 81 hasta (%81) erkek, 19 hasta (%19) kadındı. Beyin BT’si negatif olan 86 hastanın ortanca serum BNP düzeyi 5.00 pg/ml idi. Beyin BT’si pozitif olan 14 hastanın ortanca serum BNP düzeyi ise 6.15 pg/ml idi. Yapılan istatistiksel analiz sonucu bu iki grup arasında serum BNP düzeyleri açısından istatistiksel olarak anlamlı bir fark bulunmadı (p>0.05). Sonuç: Kafa travmalı hastalarda serum BNP düzeylerinin bilgisayarlı beyin tomografisi ile saptanan intrakraniyal hasarı belirlemede etkili olmadığı tespit edilmiştir.

Anahtar Kelime:

Konular: Cerrahi

Kafa travmalı hastalarda kafa içi yaralanmanın tanısında serum BNP’nin yeri

Öz:

Objective: Injuries are leading cause of death in persons less than 45 years old. Cranial computed tomography is used for diagnosis in these patients. Brain natriuretic peptide (BNP) was isolated first from the cerebral ventricles. The aim of this study is to search whether bedside BNP measurement has a place in determining intracranial injury in patients admitted to the emergency department with head trauma Matherial and Methods: The study was done prospectively in the emergency department (ED) of the Trakya University Hospital. 100 patients who were admitted to ED because of head injury and a control group of 20 healthy volunteers were enrolled to the study. Mann-Whitney U test was used to compare the binary groups, and Kruskal-Wallis test to compare multi-groups. p<0.05 was considered to be significant. Results: Eighty-one patients (81%) were male, and 19 (19%) were female. Median serum BNP level was 5.00 pg/ml in total 86 patients in Cranial CT (-) group. Mean serum BNP level in 14 patients of the Cranial CT (+) group was 6.15 pg/ml. There was no statistically significant difference between these two groups from the point of serum BNP levels ( p>0.05). Conclusions: We found in our study that serum BNP examination to show any intracranial injury in patients with head trauma was poor.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	kavalci c, AKDUR G, YEMENİCİ S, Sayhan M (2012). The value of serum BNP for the diagnosis of intracranial injury in head trauma. , 112 - 116.
Chicago	kavalci cemil,AKDUR Gökhan,YEMENİCİ Serap,Sayhan Mustafa Burak The value of serum BNP for the diagnosis of intracranial injury in head trauma. (2012): 112 - 116.
MLA	kavalci cemil,AKDUR Gökhan,YEMENİCİ Serap,Sayhan Mustafa Burak The value of serum BNP for the diagnosis of intracranial injury in head trauma. , 2012, ss.112 - 116.
AMA	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M The value of serum BNP for the diagnosis of intracranial injury in head trauma. . 2012; 112 - 116.
Vancouver	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M The value of serum BNP for the diagnosis of intracranial injury in head trauma. . 2012; 112 - 116.
IEEE	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M "The value of serum BNP for the diagnosis of intracranial injury in head trauma." , ss.112 - 116, 2012.
ISNAD	kavalci, cemil vd. "The value of serum BNP for the diagnosis of intracranial injury in head trauma". (2012), 112-116.

APA	kavalci c, AKDUR G, YEMENİCİ S, Sayhan M (2012). The value of serum BNP for the diagnosis of intracranial injury in head trauma. Türkiye Acil Tıp Dergisi, 12(3), 112 - 116.
Chicago	kavalci cemil,AKDUR Gökhan,YEMENİCİ Serap,Sayhan Mustafa Burak The value of serum BNP for the diagnosis of intracranial injury in head trauma. Türkiye Acil Tıp Dergisi 12, no.3 (2012): 112 - 116.
MLA	kavalci cemil,AKDUR Gökhan,YEMENİCİ Serap,Sayhan Mustafa Burak The value of serum BNP for the diagnosis of intracranial injury in head trauma. Türkiye Acil Tıp Dergisi, vol.12, no.3, 2012, ss.112 - 116.
AMA	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M The value of serum BNP for the diagnosis of intracranial injury in head trauma. Türkiye Acil Tıp Dergisi. 2012; 12(3): 112 - 116.
Vancouver	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M The value of serum BNP for the diagnosis of intracranial injury in head trauma. Türkiye Acil Tıp Dergisi. 2012; 12(3): 112 - 116.
IEEE	kavalci c,AKDUR G,YEMENİCİ S,Sayhan M "The value of serum BNP for the diagnosis of intracranial injury in head trauma." Türkiye Acil Tıp Dergisi, 12, ss.112 - 116, 2012.
ISNAD	kavalci, cemil vd. "The value of serum BNP for the diagnosis of intracranial injury in head trauma". Türkiye Acil Tıp Dergisi 12/3 (2012), 112-116.