The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion

SARIKAYA, SABİT; TÜRKMEN, Mehmet Muhsin; DEMİR, Serdar; ÖZKAN, Birol; Alici, Gokhan; şahin, müslüm; Kalkan, Mehmet Emin; ÇAKALAĞAOĞLU, Kamil Cantürk; BİTEKER, MURAT; YAZICIOĞLU, Mehmet Vefik

The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion

Müslüm ŞAHİN, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Serdar DEMİR, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Mehmet Emin KALKAN, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Birol ÖZKAN, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Gökhan ALICI, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Kamil Cantürk ÇAKALAĞAOĞLU, (Kartal Koşuyolu Kalp Eğitim ve Araştırma Hastanesi, Kalp ve Damar Cerrahisi Kliniği, İstanbul, Türkiye)

Mehmet Vefik YAZICIOĞLU, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Sabit SARIKAYA, (Kartal Koşuyolu Kalp Eğitim ve Araştırma Hastanesi, Kalp ve Damar Cerrahisi Kliniği, İstanbul, Türkiye)

Murat BİTEKER, (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Mehmet Muhsin TÜRKMEN (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Anadolu Kardiyoloji Dergisi

1 6

Yıl: 2014 Cilt: 14 Sayı: 1 Sayfa Aralığı: 48 - 54 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion

Öz:

Objective: The aim of this study was to evaluate the relation between blood gamma-glutamyltransferase (GGT) levels and coronary collateral circulation in patients with chronic total occlusion (CTO). Methods: Two hundred twenty-two patients with chronic stable coronary artery disease (CAD) and CTO were included in this cross-sectional, observational study. Coronary collaterals were graded from 0 to 3 according to the Rentrop method. Patients with grade 0-1 collateral develop- ment were regarded as poor collateral group (n=66) while patients with grade 2-3 collateral development were regarded as good collateral group (n=156). Statistical analysis was performed using independent samples t, Mann-Whitney U and Chi-square tests, logistic regression and receiver operator curve analysis. Results: The poor coronary collateral group had significantly higher levels of serum GGT compared to the good collateral group (p<0.001). Multiple logistic regression analysis showed that GGT levels were independent predictors of poor collateral circulation (OR-0.946, 95% CI=0.918- 0.9719, p<0.001). The result of ROC curve analysis for GGT was as following: area under the ROC curve (AUC)=0.732, 95% CI: 0.622-0.841, p<0.001. Conclusion: Higher GGT levels are associated with poor coronary collateral circulation in patients with CTO. GGT may be used to predict the grade of coronary collateral circulation in CTO patients with chronic stable CAD.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	şahin m, DEMİR S, Kalkan M, ÖZKAN B, Alici G, ÇAKALAĞAOĞLU K, YAZICIOĞLU M, SARIKAYA S, BİTEKER M, TÜRKMEN M (2014). The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. , 48 - 54.
Chicago	şahin müslüm,DEMİR Serdar,Kalkan Mehmet Emin,ÖZKAN Birol,Alici Gokhan,ÇAKALAĞAOĞLU Kamil Cantürk,YAZICIOĞLU Mehmet Vefik,SARIKAYA SABİT,BİTEKER MURAT,TÜRKMEN Mehmet Muhsin The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. (2014): 48 - 54.
MLA	şahin müslüm,DEMİR Serdar,Kalkan Mehmet Emin,ÖZKAN Birol,Alici Gokhan,ÇAKALAĞAOĞLU Kamil Cantürk,YAZICIOĞLU Mehmet Vefik,SARIKAYA SABİT,BİTEKER MURAT,TÜRKMEN Mehmet Muhsin The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. , 2014, ss.48 - 54.
AMA	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. . 2014; 48 - 54.
Vancouver	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. . 2014; 48 - 54.
IEEE	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M "The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion." , ss.48 - 54, 2014.
ISNAD	şahin, müslüm vd. "The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion". (2014), 48-54.

APA	şahin m, DEMİR S, Kalkan M, ÖZKAN B, Alici G, ÇAKALAĞAOĞLU K, YAZICIOĞLU M, SARIKAYA S, BİTEKER M, TÜRKMEN M (2014). The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. Anadolu Kardiyoloji Dergisi, 14(1), 48 - 54.
Chicago	şahin müslüm,DEMİR Serdar,Kalkan Mehmet Emin,ÖZKAN Birol,Alici Gokhan,ÇAKALAĞAOĞLU Kamil Cantürk,YAZICIOĞLU Mehmet Vefik,SARIKAYA SABİT,BİTEKER MURAT,TÜRKMEN Mehmet Muhsin The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. Anadolu Kardiyoloji Dergisi 14, no.1 (2014): 48 - 54.
MLA	şahin müslüm,DEMİR Serdar,Kalkan Mehmet Emin,ÖZKAN Birol,Alici Gokhan,ÇAKALAĞAOĞLU Kamil Cantürk,YAZICIOĞLU Mehmet Vefik,SARIKAYA SABİT,BİTEKER MURAT,TÜRKMEN Mehmet Muhsin The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. Anadolu Kardiyoloji Dergisi, vol.14, no.1, 2014, ss.48 - 54.
AMA	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. Anadolu Kardiyoloji Dergisi. 2014; 14(1): 48 - 54.
Vancouver	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion. Anadolu Kardiyoloji Dergisi. 2014; 14(1): 48 - 54.
IEEE	şahin m,DEMİR S,Kalkan M,ÖZKAN B,Alici G,ÇAKALAĞAOĞLU K,YAZICIOĞLU M,SARIKAYA S,BİTEKER M,TÜRKMEN M "The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion." Anadolu Kardiyoloji Dergisi, 14, ss.48 - 54, 2014.
ISNAD	şahin, müslüm vd. "The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion". Anadolu Kardiyoloji Dergisi 14/1 (2014), 48-54.