Yıl: 2014 Cilt: 14 Sayı: 2 Sayfa Aralığı: 162 - 169 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers

Öz:
The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

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Öz:
Objective: There are few data regarding clinical characteristics, laboratory parameters, electrocardiographic and echocardiographic findings in takotsubo cardiomyopathy patients presenting with QT prolongation. Aim of this study was to investigate the differences in these parameters between takotsubo cardiomyopathy patients presenting with and those without QT prolongation. Methods: We performed an observational retrospective study. One hundred five patients were enrolled from the takotsubo cardiomyopathy registry database and divided according to the presence of QT prolongation. Fifty patients presented with QT prolongation (QT group) and 55 did not (NQT group). Statistical analysis was performed using Student’s t-test or Mann-Whitney U test and chi-square test. Results: QT group had higher prevalence of dyspnea (66 versus 40%, p=0.008) and cardiogenic shock (46 versus 24%, p=0.016) than NQT group. QT group had higher prevalence of ST elevation (82 versus 64%, p=0.036), T wave inversion (96 versus 58%, p=0.001), ventricular tachycardia/ ventricular fibrillation (8 versus 0%, p=0.032) and classic ballooning pattern (92 versus 66%, p=0.003), but lower left ventricular ejection fraction (mean, 39.2 versus 43.5%, p=0.005). In addition, QT group had significant higher hs-C-reactive protein (median, 6.6 versus 1.7 mg/L, p=0.023), creatine kinase-MB (median, 18.6 versus 7.6 ng/mL, p=0.032) and NT-pro-brain natriuretic peptide levels (median, 3637 versus 2145 pg/mL, p=0.044). QT group required more frequent use of inotropics (46 versus 24%, p=0.016) and diuretics (58 versus 38%, p=0.042) than NQT group. Conclusion: The clinical features of takotsubo cardiomyopathy are different according to the presence of QT prolongation. The QT group was lesser likely to have preserved cardiovascular reserve and more likely to require hemodynamic support than the NQT group despite the entire prognosis of takotsubo cardiomyopathy is excellent regardless of QT prolongation. (Anadolu Kardiyol Derg 2014; 14: 162-9)
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA SONG B, CHUNG S, KIM S, KIM H, KANG G, PARK Y, CHUN W, OH J (2014). The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. , 162 - 169.
Chicago SONG Bong Gun,CHUNG Sang Man,KIM Sung Hea,KIM Hyun Joong,KANG Gu Hyun,PARK Yong Hwan,CHUN Woo Jung,OH Ju Hyeon The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. (2014): 162 - 169.
MLA SONG Bong Gun,CHUNG Sang Man,KIM Sung Hea,KIM Hyun Joong,KANG Gu Hyun,PARK Yong Hwan,CHUN Woo Jung,OH Ju Hyeon The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. , 2014, ss.162 - 169.
AMA SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. . 2014; 162 - 169.
Vancouver SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. . 2014; 162 - 169.
IEEE SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J "The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers." , ss.162 - 169, 2014.
ISNAD SONG, Bong Gun vd. "The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers". (2014), 162-169.
APA SONG B, CHUNG S, KIM S, KIM H, KANG G, PARK Y, CHUN W, OH J (2014). The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. Anadolu Kardiyoloji Dergisi, 14(2), 162 - 169.
Chicago SONG Bong Gun,CHUNG Sang Man,KIM Sung Hea,KIM Hyun Joong,KANG Gu Hyun,PARK Yong Hwan,CHUN Woo Jung,OH Ju Hyeon The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. Anadolu Kardiyoloji Dergisi 14, no.2 (2014): 162 - 169.
MLA SONG Bong Gun,CHUNG Sang Man,KIM Sung Hea,KIM Hyun Joong,KANG Gu Hyun,PARK Yong Hwan,CHUN Woo Jung,OH Ju Hyeon The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. Anadolu Kardiyoloji Dergisi, vol.14, no.2, 2014, ss.162 - 169.
AMA SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. Anadolu Kardiyoloji Dergisi. 2014; 14(2): 162 - 169.
Vancouver SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers. Anadolu Kardiyoloji Dergisi. 2014; 14(2): 162 - 169.
IEEE SONG B,CHUNG S,KIM S,KIM H,KANG G,PARK Y,CHUN W,OH J "The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers." Anadolu Kardiyoloji Dergisi, 14, ss.162 - 169, 2014.
ISNAD SONG, Bong Gun vd. "The QT prolongation and clinical features in patients with takotsubo cardiomyopathy: Experiences of two tertiary cardiovascular centers". Anadolu Kardiyoloji Dergisi 14/2 (2014), 162-169.