A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis

SAYIN, M. Raşit; ELBEY KÖPRÜ, Hatice; ELBEY, Mehmet Ali; Akyüz, Abdurrahman; BULUR, Serkan; KAYA, Mehmet G.; akdag, serkan; AKIL, M. Ata; KARAPINAR, Hekim; Ulus, Taner; Kalkan, Mehmet Emin

A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis

Mehmet Ali ELBEY, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Serkan AKDAĞ, (Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Van, Türkiye)

Mehmet Emin KALKAN, (Sağlık Bakanlığı, Kartal Koşuyolu Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Mehmet G. KAYA, (Erciyes Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Kayseri, Türkiye)

M. Raşit SAYIN, (Bülent Ecevit Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Zonguldak, Türkiye)

Hekim KARAPINAR, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Sivas, Türkiye)

Serkan BULUR, (Düzce Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Düzce, Türkiye)

Taner ULUS, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Eskişehir, Türkiye)

M. Ata AKIL, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Hatice ELBEY KÖPRÜ, (Dicle Üniversitesi, Tıp Fakültesi, Diyarbakır, Türkiye)

Abdurrahman AKYÜZ, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Diğer Yazarlar

Anadolu Kardiyoloji Dergisi

4 2

Yıl: 2013 Cilt: 13 Sayı: 6 Sayfa Aralığı: 523 - 527 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis

Öz:

Amaç: Bu çok merkezli geriye dönük çalışmada Türkiye’de infektif endokarditin klinik ve mikrobiyolojik özellikleri, ekokardiyografik bulguları ve tedavi stratejisinin belirlenmesi amaçlanmıştır. Yöntemler: Çalışmaya alınan grup 2005-2012 tarihleri arasında Türkiye’de 13 merkezde infektif endokardit tedavisi alan, retrospektif olarak 248 hastayı içermektedir. Tüm merkezler çevre hastanelerden hasta kabul eden üçüncü basamak hastaneler idi. Veriler, modifiye Duke kriterlerine göre infektif endokardit tanısı ile yatırılan hastaların arşiv bilgilerinden alınmıştır. Bulgular: Hastaların yüz otuz yedisi erkek idi. Hastalardan yüz elli sekizinde doğal kapak, yetmiş beşinde protez kapak endokarditi mevcuttu. İki yüz yirmi üç hastada (%89) vejetasyon mevcuttu ve 52 hastada vejetasyon birden fazla sayıda idi. Vejetasyon en sık mitral kapak (%43) konumunda bulundu. En sık görülen kapak hastalığı mitral yetersizliğiydi. En sık izlenen predispozan faktör romatizmal kapak hastalığı idi (%28). Pozitif kan kül- türü %65 oranında saptandı. En sık izole edilen sorumlu organizma Staphylococcus aureus idi (%29). Hastane içi ölüm hızı %33 olarak bulundu. Sonuç: Batılı ülkelerle karşılaştırıldığında ülkemizde infektif endokardit epidemiyolojisinin en önemli farklılıkları genç yaş, yüksek romatizmal kalp hastalığı prevelansı, sık enterokokal enfeksiyon ve yüksek kültür negatif sıklığıdır.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Türkiye’de 13, üçüncü basamak hastanenin katıldığı çok merkezli enfektif endokardit çalışması

Öz:

Objective: The aim of this retrospective multicenter study was to investigate the clinical manifestations, microbiological profile, echocardio- graphic findings and management strategies of infective endocarditis (IE) in Turkey. Methods: The study population consisted of 248 Turkish patients with IE treated at 13 major hospitals in Turkey from 2005 to 2012 retrospec- tively. All hospitals are tertiary referral centers, which receive patients from surrounding hospitals. Data were collected from the medical files of all patients hospitalized with IE diagnosed according to modified Duke Criteria. Results: One hundred thirty seven of the patients were males. Native valves were involved in 158 patients while in 75 participants there was prosthetic valve endocarditis. Vegetations were detected in 223 patients (89%) and 52 patients had multiple vegetations. Mitral valve was the most common site of vegetation (43%). The most common valvular pathology was mitral regurgitation. The most common predisposing factor was rheumatic valvular disease (28%). Positive culture rate was 65%. Staphylococci were the most frequent causative microorganisms iso- lated (29%) followed by enterococci (11%). In-hospital mortality rate was 33%. Conclusions: Compared to IE in developed countries younger age, higher prevalence of rheumatic heart disease, more frequent enterococci infection and higher rates of culture negativity were other important aspects of IE epidemiology in Turkey.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ELBEY M, akdag s, Kalkan M, KAYA M, SAYIN M, KARAPINAR H, BULUR S, Ulus T, AKIL M, ELBEY KÖPRÜ H, Akyüz A (2013). A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. , 523 - 527.
Chicago	ELBEY Mehmet Ali,akdag serkan,Kalkan Mehmet Emin,KAYA Mehmet G.,SAYIN M. Raşit,KARAPINAR Hekim,BULUR Serkan,Ulus Taner,AKIL M. Ata,ELBEY KÖPRÜ Hatice,Akyüz Abdurrahman A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. (2013): 523 - 527.
MLA	ELBEY Mehmet Ali,akdag serkan,Kalkan Mehmet Emin,KAYA Mehmet G.,SAYIN M. Raşit,KARAPINAR Hekim,BULUR Serkan,Ulus Taner,AKIL M. Ata,ELBEY KÖPRÜ Hatice,Akyüz Abdurrahman A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. , 2013, ss.523 - 527.
AMA	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. . 2013; 523 - 527.
Vancouver	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. . 2013; 523 - 527.
IEEE	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A "A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis." , ss.523 - 527, 2013.
ISNAD	ELBEY, Mehmet Ali vd. "A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis". (2013), 523-527.

APA	ELBEY M, akdag s, Kalkan M, KAYA M, SAYIN M, KARAPINAR H, BULUR S, Ulus T, AKIL M, ELBEY KÖPRÜ H, Akyüz A (2013). A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. Anadolu Kardiyoloji Dergisi, 13(6), 523 - 527.
Chicago	ELBEY Mehmet Ali,akdag serkan,Kalkan Mehmet Emin,KAYA Mehmet G.,SAYIN M. Raşit,KARAPINAR Hekim,BULUR Serkan,Ulus Taner,AKIL M. Ata,ELBEY KÖPRÜ Hatice,Akyüz Abdurrahman A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. Anadolu Kardiyoloji Dergisi 13, no.6 (2013): 523 - 527.
MLA	ELBEY Mehmet Ali,akdag serkan,Kalkan Mehmet Emin,KAYA Mehmet G.,SAYIN M. Raşit,KARAPINAR Hekim,BULUR Serkan,Ulus Taner,AKIL M. Ata,ELBEY KÖPRÜ Hatice,Akyüz Abdurrahman A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. Anadolu Kardiyoloji Dergisi, vol.13, no.6, 2013, ss.523 - 527.
AMA	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. Anadolu Kardiyoloji Dergisi. 2013; 13(6): 523 - 527.
Vancouver	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis. Anadolu Kardiyoloji Dergisi. 2013; 13(6): 523 - 527.
IEEE	ELBEY M,akdag s,Kalkan M,KAYA M,SAYIN M,KARAPINAR H,BULUR S,Ulus T,AKIL M,ELBEY KÖPRÜ H,Akyüz A "A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis." Anadolu Kardiyoloji Dergisi, 13, ss.523 - 527, 2013.
ISNAD	ELBEY, Mehmet Ali vd. "A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis". Anadolu Kardiyoloji Dergisi 13/6 (2013), 523-527.