Yıl: 2013 Cilt: 13 Sayı: 8 Sayfa Aralığı: 766 - 771 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study

Öz:
Amaç: Damar sertliği önemli kardiyovasküler kötü hadiselerle ilişkilidir. Kalp-ayak bileği vasküler indeks ölçümü (KAVI), sistolik kan basıncından çok az etkilenir ve damar sertliği değerlendirilmesinde yeni ve hassas bir yöntem olup ateroskleroz ve arteriolosklerozun hassas bir gösterge- sidir. Bu çalışmanın amacı kardiyak sendrom-X’li hastalarda (KSX) KAVI yöntemi ile damar sertliğinin değerlendirilmesidir. Yöntemler: Çalışmamız gözlemsel ve kesitsel nitelikte olup, bu çalışmada 49 KSX (tipik göğüs ağrısı olan, egzersiz elektrokardiyografi testinde pozitif iskemik değişiklikleri bulunan ve yapılan koroner anjiyografide normal koroner arterler tespit edilen hastalar) (29 erkek) ve 54 sağlıklı hasta (21 erkek) değerlendirildi. KAVI VaSera-1000 KAVI aletiyle ölçüldü. İstatistiksel analizde Ki-kare, t-testi, korelasyon analizi ve mantıksal regres- yon analizi kullanıldı. Bulgular: KSX hastalarında KAVI ve nabız basıncı kontrol grubuna göre anlamlı olarak daha yüksekti (sırasıyla 7,50±1,50, 6,49±0,77, p<0,001; 53,00±10,06, 47,39±8,17, p=0,002). Fakat yaş, kilo, boy, vücut kitle indeksi, bel çevresi, kalça çevresi, sistolik kan basıncı, diyastolik kan basıncı, ortalama kan basıncı, düşük ağırlıklı kolesterol, yüksek ağırlıklı kolesterol, trigliserit, kreatinin klirensi, hemoglobin, sol atriyum çapı, sol ventrikül kütlesi, sol ventrikül kütle indeksi ve ejeksiyon fraksiyonları arasında anlamlı fark yoktu. Lojistik regresyon analizinde KSX’in bağımsız öngördü- rücüsü olarak KAVI bulundu (OR=1,780, %95 CI: 1,157-2,737, p=0,009). Sonuç: KAVI, KSX hastalarında artış gösterir ve bu hastalığın bağımsız bir göstergesidir.
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Kardiyak sendrom X hastalarında kalp-ayak bileği vasküler indeksinin değerlendirilmesi: Gözlemsel bir çalışma

Öz:
Objective: Arterial stiffness is associated with major adverse cardiovascular events. Cardio-ankle vascular index (CAVI), a novel marker of arterial stiffness, which is weakly influenced by systolic blood pressure, is a sensitive marker the atherosclerosis and arteriolosclerosis. The aim of this study is to investigate arterial stiffness by CAVI in patients with cardiac syndrome X (CSX). Methods: The present study was observational and cross sectional, and involved 49 patients (26 male) with CSX (angina-like chest pain, positive electrocardiographic ischemic changes at treadmill exercise test, angiographically normal coronary arteries) and 54 healthy subjects (21 male). CAVI was measured by VaSera-1000 CAVI instrument. Statistical analysis was performed using the Chi-square, Student t-test, correlation analysis and logistic regression analysis. Results: The CAVI and pulse pressure were significantly increased in patients with CSX compared to control group (7.50±1.50, 6.49±0.77, p<0.001; 53.00±10.06, 47.39±8.17, p=0.002, consecutively). In contrast, there were no significant differences in the age, weight, height, body mass index, waist circumference, hip circumference, systolic blood pressure, diastolic blood pressure, mean blood pressure, glucose, low density lipoprotein level, high density lipoprotein level (HDL), triglyceride, estimated creatinine clearance, hemoglobin, left atrium diameter, left ven- tricular mass (LVM), LVM index and ejection fraction. CAVI was the only independent predictor of CSX in logistic regression analysis (OR=1.780, 95% CI: 1.157-2.737, p=0.009). Conclusion: CAVI is increased in syndrome X patients and is an independent predictor of this syndrome.
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA AYKAN A, GÖKDENİZ T, GÜL İ, BOYACI F, TURAN T, AYKAN ALTINTAŞ D, ÇELİK Ş, Yildiz M (2013). Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. , 766 - 771.
Chicago AYKAN Ahmet Çağrı,GÖKDENİZ Tayyar,GÜL İlker,BOYACI Faruk,TURAN Turhan,AYKAN ALTINTAŞ Duygun,ÇELİK Şükrü,Yildiz Mustafa Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. (2013): 766 - 771.
MLA AYKAN Ahmet Çağrı,GÖKDENİZ Tayyar,GÜL İlker,BOYACI Faruk,TURAN Turhan,AYKAN ALTINTAŞ Duygun,ÇELİK Şükrü,Yildiz Mustafa Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. , 2013, ss.766 - 771.
AMA AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. . 2013; 766 - 771.
Vancouver AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. . 2013; 766 - 771.
IEEE AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M "Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study." , ss.766 - 771, 2013.
ISNAD AYKAN, Ahmet Çağrı vd. "Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study". (2013), 766-771.
APA AYKAN A, GÖKDENİZ T, GÜL İ, BOYACI F, TURAN T, AYKAN ALTINTAŞ D, ÇELİK Ş, Yildiz M (2013). Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. Anadolu Kardiyoloji Dergisi, 13(8), 766 - 771.
Chicago AYKAN Ahmet Çağrı,GÖKDENİZ Tayyar,GÜL İlker,BOYACI Faruk,TURAN Turhan,AYKAN ALTINTAŞ Duygun,ÇELİK Şükrü,Yildiz Mustafa Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. Anadolu Kardiyoloji Dergisi 13, no.8 (2013): 766 - 771.
MLA AYKAN Ahmet Çağrı,GÖKDENİZ Tayyar,GÜL İlker,BOYACI Faruk,TURAN Turhan,AYKAN ALTINTAŞ Duygun,ÇELİK Şükrü,Yildiz Mustafa Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. Anadolu Kardiyoloji Dergisi, vol.13, no.8, 2013, ss.766 - 771.
AMA AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. Anadolu Kardiyoloji Dergisi. 2013; 13(8): 766 - 771.
Vancouver AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study. Anadolu Kardiyoloji Dergisi. 2013; 13(8): 766 - 771.
IEEE AYKAN A,GÖKDENİZ T,GÜL İ,BOYACI F,TURAN T,AYKAN ALTINTAŞ D,ÇELİK Ş,Yildiz M "Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study." Anadolu Kardiyoloji Dergisi, 13, ss.766 - 771, 2013.
ISNAD AYKAN, Ahmet Çağrı vd. "Assessment of cardio-ankle vascular index in patients with cardiac syndrome-X: an observational study". Anadolu Kardiyoloji Dergisi 13/8 (2013), 766-771.