Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension

Ata, Necmi; ESEN, Hamza; ESEN, FERHAN

Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension

Ferhan ESEN, (Osmangazi Üniversitesi, Tıp Fakültesi, Biyofizik Anabilim Dalı, Eskişehir, Türkiye)

Necmi ATA, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Eskişehir, Türkiye)

Hamza ESEN (Osmangazi Üniversitesi, Tıp Fakültesi, Biyofizik Anabilim Dalı, Eskişehir, Türkiye)

Anadolu Kardiyoloji Dergisi

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Yıl: 2014 Cilt: 14 Sayı: 1 Sayfa Aralığı: 3 - 8 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension

Öz:

Objective: To investigate limb specific differences in cutaneous vascular function in patients (n=33) with essential hypertension (EHT). Methods: In this observational cross-sectional study, baseline skin blood flow and the response to local heating were measured with a laser Doppler flowmeter (LDF) from the volar region of the forearm and the gaiter area of the foot at supine rest. The fractal analysis, detrended fluctua- tion analysis (DFA), was used to calculate the correlation properties of skin blood flow, LDF signal. The paired t-test and repeated measures ANOVA were used to determine the response to local heating and compare the scaling exponents of different anatomical locations respectively. Results: We found three linear scaling regions that describe the fractal behavior of LDF signal with their slopes, scaling exponents. For cardiac (αC) and cardio-respiratory (αCR) scaling exponents, thermal hyperemia (T) induced greater change in the leg (αC=1.49±0.26; αCT=1.62±0.20 p<0.01 and αCR=0.84±0.29 αCRT=0.42±0.28 p<0.001) than in forearm (αC=1.28±0.13; αCT=1.33±0.13 p>0.05 and αCR=0.73±0.15; αCRT=0.65±0.018 p<0.05). Local scal- ing exponents (αL≈αLT~1) were not significantly different (p>0.05) and, local lines did not shift in parallel with local heating in both extremities. Conclusion: The results of the present study suggest that skin microvascular function is impaired in both extremities in EHT patients. However, myogenic response is not uniform in both extremities and pronounced response to local thermal hyperemia has been observed in the gaiter area compared with the volar region. Further studies are needed to determine if these limb specific microvascular differences is the result of posture-induced structural and functional adaptation.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ESEN F, Ata N, ESEN H (2014). Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. , 3 - 8.
Chicago	ESEN FERHAN,Ata Necmi,ESEN Hamza Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. (2014): 3 - 8.
MLA	ESEN FERHAN,Ata Necmi,ESEN Hamza Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. , 2014, ss.3 - 8.
AMA	ESEN F,Ata N,ESEN H Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. . 2014; 3 - 8.
Vancouver	ESEN F,Ata N,ESEN H Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. . 2014; 3 - 8.
IEEE	ESEN F,Ata N,ESEN H "Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension." , ss.3 - 8, 2014.
ISNAD	ESEN, FERHAN vd. "Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension". (2014), 3-8.

APA	ESEN F, Ata N, ESEN H (2014). Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. Anadolu Kardiyoloji Dergisi, 14(1), 3 - 8.
Chicago	ESEN FERHAN,Ata Necmi,ESEN Hamza Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. Anadolu Kardiyoloji Dergisi 14, no.1 (2014): 3 - 8.
MLA	ESEN FERHAN,Ata Necmi,ESEN Hamza Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. Anadolu Kardiyoloji Dergisi, vol.14, no.1, 2014, ss.3 - 8.
AMA	ESEN F,Ata N,ESEN H Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. Anadolu Kardiyoloji Dergisi. 2014; 14(1): 3 - 8.
Vancouver	ESEN F,Ata N,ESEN H Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension. Anadolu Kardiyoloji Dergisi. 2014; 14(1): 3 - 8.
IEEE	ESEN F,Ata N,ESEN H "Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension." Anadolu Kardiyoloji Dergisi, 14, ss.3 - 8, 2014.
ISNAD	ESEN, FERHAN vd. "Comparative study of the upper and lower limb skin blood flow control mechanisms in patients with essential hypertension". Anadolu Kardiyoloji Dergisi 14/1 (2014), 3-8.