Streptococcal toxic shock syndrome (STSS), the most common complication of skin infection is caused by a streptoccus. This syndrome is characterized by fever, hypotension and multiple organ failure. A 64 year old male patient with sudden onset of facial swelling and redness in the eye was admitted to hospital with these complaints. The patient had bilateral periorbital edema, purulent discharge from the right eye and swelling starting from the frontal region and spreading to the right side of the neck. The gram stain of the discharge was made and gram-positive cocci were seen in the abundant leukocytes. Antibiotics, corticosteroids, respiratory and hemodynamic support were given as the treatment protocol. A 70 year old male patient with sudden swelling in the eyes and discharge from the eyes was admitted with these complaints. Bilateral lid swelling, edema, hyperemia and temperature increase were present in the patient s physical examination. The gram stain of the discharge was made and gram-positive cocci and abundant leukocytes were seen. Antibiotic treatment was given. Toxic shock syndrome caused by streptococcus is a serious clinical condition rarely encountered in emergency department. Aggressive soft tissue infections in the clinical presentation, shock, ARDS and renal failure are generally associated with bacteremia. Despite aggressive treatment, the mortality rate is 80%. (JAEM 2013; 12: 49-51)