Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma
Yıl: 2013 Cilt: 21 Sayı: 3 Sayfa Aralığı: 231 - 233 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma
Öz: Otuz yaşındaki kadın hasta sol gözünde 2 haftadır görme azalması şikayeti ile kliniğimize başvurdu. Hastanın hikayesin- den 6 ay önce evre 4 periferal T-hücreli non-Hodgkin lenfoma tanısı ile kemoterapi görmeye başladığı öğrenildi. Fundosko- pik muayenede sağ gözde tipik donmuş ağaç dal anjitisi görünümünde yaygın vasküler kılıflanma ve retinal hemorajilerle ilişkili beyaz retinal lezyonlar mevcuttu. Sol göz fundoskopik muayenede retina flue olarak değerlendirilmekle birlikte optik disk çevresinde ve periferik retina da eksudatif lezyonlar görülmekteydi. Serolojik testler HIV ve CMV Ig M testi negatif, CMV Ig G positif olarak sonuçlandı. Hastaya CMV retiniti tanısı konularak intravenöz gansiklovir tedavisi başlanıldı. Gansiklovir 4 ay sonra kesildi, ancak 2 hafta sonra her iki gözde CMV retiniti nüks etti. Genel durumu bozuk olan hasta hematoloji servisine transfer edildi ancak hasta kaybedildi. Sonuç olarak, bu tür olgularda hastalığın nüksetmemesi için en az 6 ay gansiklovir tedavisi önermekteyiz.
Anahtar Kelime: Konular:
Non-hodgkin lenfomalı bir olguda nüks sitomegalovirüs retiniti
Öz: A 30-year-old female patient presented at our clinic suffering from decreasing vision in the left eye for the last 2 weeks. According to the patient file, she had been started on chemotherapy six months ago due to a diagnosis of stage 4 peripheral T-cell non-Hodgkin’s lymphoma. There was common vascular sheathing with an appearance of typical frosted branch an- giitis and white retinal lesions related to retinal hemorrhages in the right eye on fundoscopic examination. The left retina was hazy on fundoscopic examination but exudative lesions were observed around the optic disc and macula and on the peripheral retina. HIV and CMV IgM tests were negative on serological tests, but the CMV IgG test was positive. CMV retinitis was diagnosed and intravenous ganciclovir administered as the treatment. Ganciclovir was stopped after 4 months, but CMV retinitis recurred in both eyes two weeks later. The patient was transferred to the hematology service as he was in poor general condition but later passed away. In conclusion, we recommend at least six months ganciclovir therapy for such cases to prevent the recurrence of the disease.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Bibliyografik
- 1. Bloom JN, Palestine AG. The diagnosis of cytomegalovirus retinitis. Ann Intern Med 1988;109:963-9. 2. Hoover DR, Peng Y, Saah A, et al. Occurrence of cytomegalo- virus retinitis after human immunodeficiency virus immuno- suppression. Arch Ophthalmol 1996;114:821-7. 3. Sugar EA, Jabs DA, Ahuja A, et al. Incidence of Cytomega- lovirus Retinitis in the Era of Highly Active Antiretroviral Therapy. Am J Ophthalmol 2012;153:1016-24. 4. Vote B, Russell M, Polkinghorne P. Recurrent cytomegalovirus retinitis in a patient with a normal lymphocyte count who had undergone splenectomy for lymphoma. Retina 2005;25:220-1. 5. Chawla R, Venkatesh P, Garg SP, et al. Cytomegalovirus reti- nitis in a patient with non-Hodgkin’s lymphoma: a diagnostic dilemma. Eur J Ophthalmol 2005;15:153-7. 6. Gooi P, Farmer J, Hurley B, et al. Cytomegalovirus reti- nitis mimicking intraocular lymphoma. Clin Ophthalmol 2008;2:969-71. 7. Ar MC, Ozbalak M, Tuzuner N, et al. Severe bone marrow failure due to valganciclovir overdose after renal transplanta- tion from cadaveric donors: four consecutive cases. Transplant Proc 2009;41:1648-53. 8. Oktavec KC, Nolan K, Brown DM, et al. Clinical outcomes in patients with cytomegalovirus retinitis treated with ganciclo- vir ımplant. Am J Ophthalmol 2012;153:728-33.
| APA | ÇETİN A, KILIÇ R, GÖKTOLGA G, Demir S, ÇOMÇALI ÜSTÜN S, ÇAKMAK Y (2013). Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. , 231 - 233. |
| Chicago | ÇETİN Abdi Bahadır,KILIÇ Raşit,GÖKTOLGA Gökay,Demir Selim,ÇOMÇALI ÜSTÜN Sebile,ÇAKMAK Yasin Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. (2013): 231 - 233. |
| MLA | ÇETİN Abdi Bahadır,KILIÇ Raşit,GÖKTOLGA Gökay,Demir Selim,ÇOMÇALI ÜSTÜN Sebile,ÇAKMAK Yasin Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. , 2013, ss.231 - 233. |
| AMA | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. . 2013; 231 - 233. |
| Vancouver | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. . 2013; 231 - 233. |
| IEEE | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y "Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma." , ss.231 - 233, 2013. |
| ISNAD | ÇETİN, Abdi Bahadır vd. "Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma". (2013), 231-233. |
| APA | ÇETİN A, KILIÇ R, GÖKTOLGA G, Demir S, ÇOMÇALI ÜSTÜN S, ÇAKMAK Y (2013). Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. Retina-Vitreus, 21(3), 231 - 233. |
| Chicago | ÇETİN Abdi Bahadır,KILIÇ Raşit,GÖKTOLGA Gökay,Demir Selim,ÇOMÇALI ÜSTÜN Sebile,ÇAKMAK Yasin Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. Retina-Vitreus 21, no.3 (2013): 231 - 233. |
| MLA | ÇETİN Abdi Bahadır,KILIÇ Raşit,GÖKTOLGA Gökay,Demir Selim,ÇOMÇALI ÜSTÜN Sebile,ÇAKMAK Yasin Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. Retina-Vitreus, vol.21, no.3, 2013, ss.231 - 233. |
| AMA | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. Retina-Vitreus. 2013; 21(3): 231 - 233. |
| Vancouver | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma. Retina-Vitreus. 2013; 21(3): 231 - 233. |
| IEEE | ÇETİN A,KILIÇ R,GÖKTOLGA G,Demir S,ÇOMÇALI ÜSTÜN S,ÇAKMAK Y "Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma." Retina-Vitreus, 21, ss.231 - 233, 2013. |
| ISNAD | ÇETİN, Abdi Bahadır vd. "Recurrent cytomegalovirus retinitis in a patient with non-hodgkin’s lymphoma". Retina-Vitreus 21/3 (2013), 231-233. |
