Yıl: 2013 Cilt: 9 Sayı: 4 Sayfa Aralığı: 182 - 185 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Pure and mixed mucinous carcinoma of the breast

Öz:
Amaç: Müsinöz meme kanserleri nispeten nadirdir ve pür halinin tüm meme karsinomları içerisinde görülme sıklığı %2’dir. Pür ve mikst tipleritarif edilmiştir. Bu çalışmada müsinöz meme kanserindeki tedavi yaklaşım-ları ve prognostik özelliklerin değerlendirilmesi amaçlanmıştır. Yöntem ve Gereçler: Bu çalışmada kliniğimizde 2004-2011 yılları ara- sında müsinöz meme kanseri nedeniyle ameliyat edilen 24 olgu patolojiktanılarına göre pür ve miks olarak iki gruba ayrıldı. Bulgular: Olguların tamamı bayan ve ortanca yaşı 54(37-84) idi. Miks müsinöz meme karsinomlu hasta sayısı 15 (%62.5), pür müsinöz meme karsinomlu hasta sayısı ise dokuz (%37,5) idi. Hastaların ortanca izlem süresi 40 (12-84) aydı. Pür grupta aksiller lenf nodu metastazı sadece bir (%11) olguda mevcut olup miks grupta ise dokuz olguda saptanmış olup istatistiksel olarak anlamlı fark vardı (p=0,001). Sadece miks grupta bir has- tada lokal nüks görüldü. Miks grupta uzak metastazı olan hasta sayısı altı iken, pür grupta uzak metastaz saptanmadı. İki grup arasında uzak metastaz gelişimi açısından anlamlı fark vardı (p=0,028). Sonuç: Pür müsinöz meme kanserlerinin diğer invaziv meme kanserlerine göre prognozu oldukça iyidir. Pür müsinöz meme karsinomları onkolojik prensiplere uyularak yapılan tedaviyle yüz güldürücü neticeler alınabilen bir kanser türüdür.
Anahtar Kelime:

Konular: Cerrahi

Pür ve miks müsinöz meme karsinomu

Öz:
Objective: Mucinous carcinoma of the breast is relatively rare and theprevalence of its pure form among all carcinomas of the breast is 2%. Its pureand mixed types have been defined. This study aims at evaluating therapeuticapproaches to and prognostic features of mucinous carcinoma of the breast.Materials and Methods: The 24 patients, who had undergone surgerybecause of mucinous breast cancer at our clinic between 2004 and 2011,were categorized into two groups as pure and mixed according to theirpathological diagnoses within the scope of the study.Results: All the cases were female and the median age was 54 years (37-84). While the number of patients with mixed mucinous carcinoma of the breast was 15, the number of patients with pure mucinous carcinoma of the breast was nine (37.5%). The median follow-up period of the patients was 40 (12-84) months. Axillary lymph node metastasis was seen only in one pa- tient within the pure group (11%) while it was seen in nine cases in the mixed group. Thus, there was a statistically significant difference between the groups (p=0.001). Local recurrence was seen only in one patient in the mixed group. While there were six patients with distant metastases in the mixed group, there was no distant metastasis in the pure group (p=0.028). Conclusion: Pure mucinous breast cancers have better prognoses than other invasive breast cancers. Pure mucinous carcinoma of the breast is a type of cancer with which physicians may achieve gratifying results through treatment carried out in line with oncological principles.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. André S, Cunha F, Bernardo M, Meneses e Sousa J, Cortez F, Soares J. Mucinous carcinoma of the breast: a pathologic study of 82 cases. J Surg Oncol 1995;58:162-7. (PMID: 7898111)
  • 2. Toikkanen S, Kujari H. Pure and mixed mucinous carcinomas of the breast: a clinicopathologic analysis of 61 cases with long-term follow-up. Hum Pathol 1989;20:758-64. (PMID: 2545592)
  • 3. Monzawa S, Yokokawa M, Sakuma T, Takao S, Hirokaga K, Hanioka K, et al. Mucinous carcinoma of the breast: MRI features of pure and mixed forms with histopathologic correlation. AJR Am J Roentgenol 2009;192:125-31. (PMID: 19234240)
  • 4. Di Saverio S, Gutierrez J, Avisar E. A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma. Breast Can- cer Res Treat 2008;111:541-7. (PMID: 18026874)
  • 5. Silverberg SG, Kay S, Chitale AR, Levitt SH. Colloid carcinoma of the breast. Am J Clin Pathol 1971;55:355-63. (PMID: 4323690)
  • 6. Memis A, Ozdemir N, Parildar M, Ustun EE, Erhan Y. Mucinous (collo- id) breast cancer: mammographic and US features with histologic correla- tion. Eur J Radiol 2000;35: 39-43. (PMID: 10930764)
  • 7. Matsuda M, Yoshimoto M, Iwase T, Takahasi K, Kasumi F, Akiyama F, et al. Mammographic and clinicopathological features of mucinous carcino- ma of the breast. Breast Cancer 2000;7:65-70. (PMID: 11029773)
  • 8. Dhillon R, Depree P, Metcalf C, Wylie E. Screen-detected mucinous bre- ast carcinoma: potential for delayed diagnosis. Clinical Rad 2006;61:423- 30. (PMID: 16679116)
  • 9. Vo T, Xing Y, Meric-Bernstam F, Mirza N, Vlastos G, Symmans WF, et al. Long-term outcomes in patients with mucinous, medullary, tubular, and invasive ductal carcinomas after lumpectomy. Am J Surg 2007;194:527- 31. (PMID: 17826073)
  • 10. Diab SG, Clark GM, Osborne CK, Libby A, Allred DC, Elledge RM. Tu- mor characteristics and clinical outcome of tubular and mucinous breast carcinomas. J Clin Oncol 1999;17:1442-8. (PMID: 10334529)
  • 11. Louwman MW, Vriezen M, van Beek MW, Nolthenius-Puylaert MC, van der Sangen MJ, Roumen RM, et al. Uncommon breast tumors in perspective: incidence, treatment, and survival in The Netherlands. Int J Cancer 2007;121:127-35. (PMID: 17330844)
  • 12. Komaki K, Sakamoto G, Sugano H, Morimoto T, Monden Y. Mucinous carcinoma of the breast in Japan. A prognostic analysis based on morpho- logic features. Cancer 1988;61: 989-96. (PMID: 2827884)
  • 13. Cao AY, He M, Liu ZB, Di GH, Wu J, Lu JS, et al. Outcome of pure mucinous breast carcinoma compared to infiltrating ductal carcinoma: a population-based study from China. Ann Surg Oncol 2012;19:3019-27. (PMID: 22451233)
  • 14. Bae SY, Choi MY, Cho DH, Lee JE, Nam SJ, Yang JH. Mucinous carci- noma of the breast in comparison with invasive ductal carcinoma: clini- copathologic characteristics and prognosis. J Breast Cancer 2011;14:308- 13. (PMID: 22323918)
  • 15. Dogan E, Aksoy S, Dizdar O, Arslan C, Dede DS, Ozisik Y, et al. Pure mucinous carcinoma of the breast: a single center experience. J BUON 2011;16:565-7. (PMID: 22006768)
APA Gündeş E, AKSOY F, VATANSEV C, CAKIR M (2013). Pure and mixed mucinous carcinoma of the breast. , 182 - 185.
Chicago Gündeş Ebubekir,AKSOY FARUK,VATANSEV Celalettin,CAKIR Murat Pure and mixed mucinous carcinoma of the breast. (2013): 182 - 185.
MLA Gündeş Ebubekir,AKSOY FARUK,VATANSEV Celalettin,CAKIR Murat Pure and mixed mucinous carcinoma of the breast. , 2013, ss.182 - 185.
AMA Gündeş E,AKSOY F,VATANSEV C,CAKIR M Pure and mixed mucinous carcinoma of the breast. . 2013; 182 - 185.
Vancouver Gündeş E,AKSOY F,VATANSEV C,CAKIR M Pure and mixed mucinous carcinoma of the breast. . 2013; 182 - 185.
IEEE Gündeş E,AKSOY F,VATANSEV C,CAKIR M "Pure and mixed mucinous carcinoma of the breast." , ss.182 - 185, 2013.
ISNAD Gündeş, Ebubekir vd. "Pure and mixed mucinous carcinoma of the breast". (2013), 182-185.
APA Gündeş E, AKSOY F, VATANSEV C, CAKIR M (2013). Pure and mixed mucinous carcinoma of the breast. Meme Sağlığı Dergisi, 9(4), 182 - 185.
Chicago Gündeş Ebubekir,AKSOY FARUK,VATANSEV Celalettin,CAKIR Murat Pure and mixed mucinous carcinoma of the breast. Meme Sağlığı Dergisi 9, no.4 (2013): 182 - 185.
MLA Gündeş Ebubekir,AKSOY FARUK,VATANSEV Celalettin,CAKIR Murat Pure and mixed mucinous carcinoma of the breast. Meme Sağlığı Dergisi, vol.9, no.4, 2013, ss.182 - 185.
AMA Gündeş E,AKSOY F,VATANSEV C,CAKIR M Pure and mixed mucinous carcinoma of the breast. Meme Sağlığı Dergisi. 2013; 9(4): 182 - 185.
Vancouver Gündeş E,AKSOY F,VATANSEV C,CAKIR M Pure and mixed mucinous carcinoma of the breast. Meme Sağlığı Dergisi. 2013; 9(4): 182 - 185.
IEEE Gündeş E,AKSOY F,VATANSEV C,CAKIR M "Pure and mixed mucinous carcinoma of the breast." Meme Sağlığı Dergisi, 9, ss.182 - 185, 2013.
ISNAD Gündeş, Ebubekir vd. "Pure and mixed mucinous carcinoma of the breast". Meme Sağlığı Dergisi 9/4 (2013), 182-185.