Effects of spaceflight on cells of bone marrow origin

ÖZÇİVİCİ, ENGİN

Effects of spaceflight on cells of bone marrow origin

Engin ÖZÇİVİCİ (İzmir Teknoloji Enstitüsü Makina Mühendisliği, Bölümü, İzmir, Türkiye)

Turkish Journal of Hematology

3 0

Yıl: 2013 Cilt: 30 Sayı: 1 Sayfa Aralığı: 1 - 7 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Effects of spaceflight on cells of bone marrow origin

Öz:

Uzay istasyonları, Ay ve uzak gezegenlerde insan yaşantısının sürdürülmesi her ne kadar bilim kurgu romanlarının öğesi olsa da, bugün uzay ajanslarının kısa vadeli hedefleri arasında yer göstermeye başlamıştır. Bu bilimsel derleme, insanoğlunun uzun süreli uzay uçuşları sırasında karşılaştığı biyomedikal problemleri sunma hedefiyle yazılmıştır. Özellikle kemik iliği kökenli kemik, kan ve bağışıklık hücrelerine yoğunlaşılan derlemede bu hücrelerin ağırlıksız ortamda yaşadığı sayısal ve fonksiyonel değişiklikler sunulmuştur. Mekanik kuvvet yoksunluğunun sadece özelleşmiş hücrelerde değil aynı zamanda kemik iliği içinde varolan öncül kök hücrelere olan etkisi de derlemeye eklenmiştir. Özetle, uzay uçuşları kemik iliğinde bulunan bütün hücrelerin düzenini bozduğu için, uzun süreli uçuşlarının sağlıklı gerçekleşme potansiyelinin ağırlıksız ortamın yarattığı ters etkileri ortadan kaldırabilecek yenilikçi biyomedikal çözümler ve uzay teknolojilerine bağımlı olacağı öngörülmüştür.

Anahtar Kelime:

Konular: Hematoloji

Uzay uçuşlarının kemik iliği kökenli hücreler üzerindeki etkileri

Öz:

Once only a subject for science fiction novels, plans for establishing habitation on space stations, the Moon, and distant planets now appear among the short-term goals of space agencies. This article reviews studies that present biomedical issues that appear to challenge humankind for long-term spaceflights. With particularly focus on cells of bone marrow origin, studies involving changes in bone, immune, and red blood cell populations and their functions due to extended weightlessness were reviewed. Furthermore, effects of mechanical disuse on primitive stem cells that reside in the bone marrow were also included in this review. Novel biomedical solutions using space biotechnology will be required in order to achieve the goal of space exploration without compromising the functions of bone marrow, as spaceflight appears to disrupt homeostasis for all given cell types.

Anahtar Kelime:

Konular: Hematoloji

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	ÖZÇİVİCİ E (2013). Effects of spaceflight on cells of bone marrow origin. , 1 - 7.
Chicago	ÖZÇİVİCİ ENGİN Effects of spaceflight on cells of bone marrow origin. (2013): 1 - 7.
MLA	ÖZÇİVİCİ ENGİN Effects of spaceflight on cells of bone marrow origin. , 2013, ss.1 - 7.
AMA	ÖZÇİVİCİ E Effects of spaceflight on cells of bone marrow origin. . 2013; 1 - 7.
Vancouver	ÖZÇİVİCİ E Effects of spaceflight on cells of bone marrow origin. . 2013; 1 - 7.
IEEE	ÖZÇİVİCİ E "Effects of spaceflight on cells of bone marrow origin." , ss.1 - 7, 2013.
ISNAD	ÖZÇİVİCİ, ENGİN. "Effects of spaceflight on cells of bone marrow origin". (2013), 1-7.

APA	ÖZÇİVİCİ E (2013). Effects of spaceflight on cells of bone marrow origin. Turkish Journal of Hematology, 30(1), 1 - 7.
Chicago	ÖZÇİVİCİ ENGİN Effects of spaceflight on cells of bone marrow origin. Turkish Journal of Hematology 30, no.1 (2013): 1 - 7.
MLA	ÖZÇİVİCİ ENGİN Effects of spaceflight on cells of bone marrow origin. Turkish Journal of Hematology, vol.30, no.1, 2013, ss.1 - 7.
AMA	ÖZÇİVİCİ E Effects of spaceflight on cells of bone marrow origin. Turkish Journal of Hematology. 2013; 30(1): 1 - 7.
Vancouver	ÖZÇİVİCİ E Effects of spaceflight on cells of bone marrow origin. Turkish Journal of Hematology. 2013; 30(1): 1 - 7.
IEEE	ÖZÇİVİCİ E "Effects of spaceflight on cells of bone marrow origin." Turkish Journal of Hematology, 30, ss.1 - 7, 2013.
ISNAD	ÖZÇİVİCİ, ENGİN. "Effects of spaceflight on cells of bone marrow origin". Turkish Journal of Hematology 30/1 (2013), 1-7.