Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus

Kırbaş, Aynur; GÜVEN GÜVENDAĞ, Emine Seda; ŞAHİN KIR, Figen; BAYOĞLU TEKİN, Yeşim; YAZICI, Zihni Açar

Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus

Yeşim BAYOĞLU TEKİN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Rize, Türkiye)

Emine Seda GÜVEN GÜVENDAĞ, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Rize, Türkiye)

Zihni Açar YAZICI, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Rize, Türkiye)

Aynur KIRBAŞ, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Biyokimya Ana Bilim Dalı, Rize, Türkiye)

Figen ŞAHİN KIR (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Rize, Türkiye)

GORM:Gynecology Obstetrics & Reproductive Medicine

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Yıl: 2014 Cilt: 20 Sayı: 3 Sayfa Aralığı: 159 - 162 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus

Öz:

AMAÇ: Bu çalışmanın amacı Cooper T ve LevonorgestrelliRahim içi araçların (LNG-IUD) servikal mukus proteoglikan yapısı üzerine etkisinin değerlendirilmesidir.GEREÇ VE YÖNTEM: Bu kesitsel çalışma bir üniversite hastanesi jinekoloji polikliniğinde altı ay süre ile yürütülmüştür. Dahiledilme kriterleri 18-50 yaş arasında olmak ve kontraseptif yöntem olarak Copper T ya da LNG-IUD kullanmaktır. Mu kus örnekleri menstural kanamadan 7 gün sonra elde edilmiş ve servikal mukusta Hyaluronan (HA), Heparin Sulfat (HS) ve sulfatlanmış glikozaminoglikan (s-GAG) seviyeleri değerlendirilmiştir.BULGULAR: Copper T ve LNG-IUD gruplarında HA, HS ve s-GAG seviyeleri kontrol grubundan daha yüksektir. Ancak farksadece s-GAG için istatistiksel olarak anlamlıdır (p<0,001).SONUÇ: Bakırlı ve levonorgestrelli rahim içi kontraseptif araçların servikal mukusun proteoglikan içeriği üzerinde önemli etkileri vardır.

Anahtar Kelime:

Konular: Kadın Hastalıkları ve Doğum

Cooper T ve Levonorgestrelli rahim içi araçların servikal mukus proteoglikan yapısı üzerine etkilerinin karşılaştırılması

Öz:

OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD(LNG-IUD) on the proteoglycan composition of cervical mucus.STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinicof a University hospital for a six month period. The study participants were between 18-50 years old,using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 daysafter the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-gly-cosaminoglycans (s-GAG) were evaluated.RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher thanthose of the controls. However, the difference was statistically significant only for s-GAG (p<0.001).CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effectson proteoglycan component of cervical mucus.

Anahtar Kelime:

Konular: Kadın Hastalıkları ve Doğum

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	BAYOĞLU TEKİN Y, GÜVEN GÜVENDAĞ E, YAZICI Z, Kırbaş A, ŞAHİN KIR F (2014). Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. , 159 - 162.
Chicago	BAYOĞLU TEKİN Yeşim,GÜVEN GÜVENDAĞ Emine Seda,YAZICI Zihni Açar,Kırbaş Aynur,ŞAHİN KIR Figen Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. (2014): 159 - 162.
MLA	BAYOĞLU TEKİN Yeşim,GÜVEN GÜVENDAĞ Emine Seda,YAZICI Zihni Açar,Kırbaş Aynur,ŞAHİN KIR Figen Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. , 2014, ss.159 - 162.
AMA	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. . 2014; 159 - 162.
Vancouver	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. . 2014; 159 - 162.
IEEE	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F "Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus." , ss.159 - 162, 2014.
ISNAD	BAYOĞLU TEKİN, Yeşim vd. "Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus". (2014), 159-162.

APA	BAYOĞLU TEKİN Y, GÜVEN GÜVENDAĞ E, YAZICI Z, Kırbaş A, ŞAHİN KIR F (2014). Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. GORM:Gynecology Obstetrics & Reproductive Medicine, 20(3), 159 - 162.
Chicago	BAYOĞLU TEKİN Yeşim,GÜVEN GÜVENDAĞ Emine Seda,YAZICI Zihni Açar,Kırbaş Aynur,ŞAHİN KIR Figen Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. GORM:Gynecology Obstetrics & Reproductive Medicine 20, no.3 (2014): 159 - 162.
MLA	BAYOĞLU TEKİN Yeşim,GÜVEN GÜVENDAĞ Emine Seda,YAZICI Zihni Açar,Kırbaş Aynur,ŞAHİN KIR Figen Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.20, no.3, 2014, ss.159 - 162.
AMA	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. GORM:Gynecology Obstetrics & Reproductive Medicine. 2014; 20(3): 159 - 162.
Vancouver	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus. GORM:Gynecology Obstetrics & Reproductive Medicine. 2014; 20(3): 159 - 162.
IEEE	BAYOĞLU TEKİN Y,GÜVEN GÜVENDAĞ E,YAZICI Z,Kırbaş A,ŞAHİN KIR F "Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus." GORM:Gynecology Obstetrics & Reproductive Medicine, 20, ss.159 - 162, 2014.
ISNAD	BAYOĞLU TEKİN, Yeşim vd. "Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus". GORM:Gynecology Obstetrics & Reproductive Medicine 20/3 (2014), 159-162.