One of the most important thing that affects theemployees success, happiness and productivityin the organisation is their loyalty to the organisation and their job satisfaction. This research wasconducted in order to determine the level of theinstutional loyalties and the job satisfaction of theemployees who work in the hospitals , the relationship between them and the effects of the socio-demographic characteristics on institutionalloyalty and job satisfaction.The research wasconducted in Haydarpaşa Numune Training andResearch Hospital in 2010 and has descriptiveand inferential nature.The data was collected by face to face questionnaire method and 5-Likert Scale was used.Withrandom sampling method 460 employees werechosen as a sample among the recearch groupconsisting of 1350 employees and 451 questionnaires which were fully answered were evaluated.In the analysis of the data for independent samples ,T test and one- way analysis of variance were used in the scope ofSPSSfor Windows 15.0 software, and in order to determine the differences Tukey and Scheffe wereused . The relationship between the variableswas tested by Correlation analysis.When employees organisational loyalty and jobsatisfaction are examined , the average of emotional loyalty is approximately 2.96 , continuanceloyalty is found as 2.91, normative loyalty is 3.2,general institutional loyalty (overall corporatecommitment) as 3.05, internal job satisfaction isapproximately 3.24 , external job satisfaction is2.70 and general (overall) job satisfaction is found as 3.03 . The average level of job satisfaction and organisational loyalty of the hospital staffis moderate and there is a relationship and interaction between them.In the hospitals , studies should be made to increase organisational loyalty and job satisfaction. We expect that the research will have a lot ofcontributions to the similar researches and willsupport the top management decisions.