Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery

ERTÜRK, Engin; GEZE SAATÇI, ŞÜKRAN; Ufuk DOĞAN, Bahanur; Cekic, Bahanur; BEŞİR, Ahmet

Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery

Bahanur ÇEKİÇ, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Yoğun Bakım Bölümü, Trabzon, Türkiye)

Bahanur Ufuk DOĞAN, (Numune Eğitim Araştırma Hastanesi, Anesteziyoloji ve Yoğun Bakım Bölümü, Trabzon, Türkiye)

ŞÜKRAN GEZE SAATÇI, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Yoğun Bakım Bölümü, Trabzon, Türkiye)

Engin ERTÜRK, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Yoğun Bakım Bölümü, Trabzon, Türkiye)

Ahmet BEŞİR (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Yoğun Bakım Bölümü, Trabzon, Türkiye)

European Journal of General Medicine

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Yıl: 2013 Cilt: 10 Sayı: 2 Sayfa Aralığı: 74 - 78 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery

Öz:

Biz çalışmamızda inguinal herni ve inmemiş testis operasyonu geçiren çocuklarda levobupivakain ile tramadolun yara yeri infiltra- syon yöntemiyle postoperatif ağrıyı azaltmadaki etkinliklerini karşılaştırmayı amaçladık. Genel anestezi altında elektif inguinal herni ve inmemiş testis operasyonu geçiren, ASA I-II risk grubunda, 1-6 yaş arası 80 çocuk hastanın dosya kayıtları retrospektif olarak incelendi. Cerrahi bitiminde, cilt kapanmadan önce yara dudaklarına 2 mg/kg tramadol içeren solusyondan 0.2 ml/kg olacak şekilde yapılanlar T Grubu, %0.25 lik levobupivakain solusyondan 0.2 ml/kg olacak şekilde yapılanlar L Grubu olarak kabul edildi. Hemodinamik parametreler, CHEOPS ağrı skoru, ek analjezik tüketimi ve yan etkiler dosyalardan incelenerek kaydedildi. Hastaların CHEOPS skoru L grubunda T grubu ile kıyaslandığında 4. ve 6. saatte daha yüksek saptandı (p<0.01). Ek analjezik tüketimi bakımından, Grup Tde ev periyodu dönemi parasetamol tüketimi Grup L 'den daha düşüktü (p<0.05). Sonuç olarak biz çalışmamızda; inguinal herni onarımı ve inmemiş testis operasyonu geçiren çocuklarda yara yerine infiltre edilen tramadolun levobupivakaine göre daha uzun analjezi süresi sağladığını ve ek analjezik ihtiyacının daha az olduğunu bulduk.

Anahtar Kelime:

Konular: Cerrahi

Çocuklarda levobupivakain ile tramadolun yara yeri infiltrasyon yöntemiyle postoperatif ağrıyı azaltmadaki etkinliklerinin karşılaştırılması

Öz:

The aim of this study was to compare the effects of wound infiltration with levobupivacaine and tramadol in reducing postopera- tive pain in children undergoing unilateral inguinal hernia and undescended testis surgery. Under general anesthesia for elective unilateral inguinal hernia and undescended testis underwent surgery, ASA I-II, 80 children between the ages of 1-6 records in the patient's file was reviewed. The patients who were given 2mg.kg-1 tramadol in saline solution as prepared 0,2 ml.kg-1 into the sur- gical incision area by the surgeon at the end of the operation were accepted as Group T, who were given 0.25% levobupivacaine as 0.2 ml.kg-1 were accepted as Group L. Hemodynamic parameters, CHEOPS pain scores, additional analgesic consumption, adverse effects were recorded from the files. Patients CHEOPS were significantly higher in Group L compared to Group T at 4 and 6 hours (p<0.01). In respect to supplementary analgesic administration, paracetamol consumption in Group T was lower than in Group L during home period (p<0.05). We observed that wound infiltration of tramadol provided longer-lasting analgesia compared to levobupivacaine in children undergoing unilateral inguinal hernia repair and undescended testis surgery, and that the requirement for additional analgesic was lower.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1.Rawal N, Axelsson K, Hylander J, et al. Postoperative patient controlled local anesthetics administration at home. Anesth Analg 1998; 86:86-9.
2.Gristwood RW. Cardiac and CNS toxicity of levobupiva- caine: strengths of evidence for advantage over bupiva- caine. Drug Saf 2002;25:153-63.
3.Burlacu CL, Buggy DJ. Update on local anesthetics: fo- cus on levobupivacaine. Ther Clin Risk Manag 2008; 4 (2): 381-92
4.Matsota P, Papageorgiou-Brousta M, Kostopanagiotou G. Wound infiltration with levobupivacaine: an alternative method of postoperative pain relief after inguinal hernia repair in children. Eur J Pediatr Surg 2007;17(4):270-4.
5.Bay-Nielsen M, Klarskov B, Bech K, Andersen J, Kehlet H. Levobupivacaine and bupivacaine as infiltration anaesthe- sia in inguinal herniorrhaphy.Br J Anaesth 1999; 82:280-2
6.Jaffe RA, Rowe MA. A comparison of the local anesthetic effects of meperidine, fentanyl, and sufentanil on dorsal root axons. Anesth Analg 1996; 83: 77681.
7.Mert T, Gunes Y, Guven M, Gunay I, Ozcengiz D. Comparison of nerve conduction blocks by an opioid and a local anesthetic. Eur J Pharmacol 2002;439:7781.
8. Altunkaya H, Ozer Y, Kargi E, et al. The postoperative analgesic effect of tramadol when used as subcutaneous local anesthetic. Anesth Analg 2004;99:14614.
9.Khajavi MR, Aghili SB, Moharari RS, et al. Subcutaneous tramadol infiltration at the wound site versus intravenous administration after pyelolithotomy. Ann Pharmacother 2009;43(3):430-5.
10. Ugur MB, Yilmaz M, Altunkaya H, Cinar F, Ozer Y, Beder L. Effects of intramuscular and peritonsillar injection of tra- madol before tonsillectomy: a double blind, randomized, placebo-controlled clinical trial. Int J Otorhinolaryngol 2008;72(2):241-8.
11. Kaki AM, Al Marakbi W. Post-herniorrhapy infiltration of tramadol versus bupivacaine for postoperative pain re- lief: a randomized study. Ann Saudi Med 2008;28(3):165-8
12. McGrath PJ, Johnson G, Goodman JT, et al. In: Fields HL, Dubner R, Cervero F, editors. The CHEOPS. A Behavioural Scale to Measure Postoperative Pain in Children. New York, USA: Raven Press; 1985. p. 395-402.
13. Covino BG, Wildsmith JAW. Clinical pharmacology of local anesthetic agents. In Cousins MJ, Bridenbaugh PO, eds. Neuronal Blockade. 3rd. Ed. Philadelphia: Lippincott- Raven, 1998. p.107
14. Cınar SO, Kum U, Cevizci N, Kayaoglu S, Oba S. Effects of levobupivacaine infiltration on postoperative analgesia and stress response in children following inguinal hernia repair. Eur J Anaesthesiology 2009;26:43043
15. Ellmauer S, Dick W, Otto S, Müller H. Different opioids in patients at cardiovascular risk. Comparison of central and peripheral hemodynamic adverse effects. Anaesthesist 1994;43(11):743-9
16. Pang WW, Huang PY, Chang DP, Huang MH. The peripheral analgesic effect of tramadol in reducing propofol injec- tion pain: a comparison with lidocaine. Reg Anesth Pain Med 1999;24:2469.
17. Pang WW, Mok MS, Chang DP, Yang TF, Lin CH, Huang MH. Intradermal injection of tramadol has local anesthetic ef- fect: a comparison with lidocaine. Acta Anaesthesiol Sin 1998;36:1336.
18. Tsai YC, Chang PJ, Jou IM. Direct tramadol application on sciatic nerve inhibits spinal somatosensory evoked poten- tials in rats. Anesth Analg 2001;92:154751.
19. Demiraran Y, Ilce Z, Kocaman B, Bozkurt P. Does tramadol wound infiltration offer an advantage over bupivacaine for postoperative analgesia in children following herni- otomy? Pediatric Anesthesia 2006;16:104750
20. Radbruch L, Grond S, Lehmann KA. A riskbenefit assess- ment of tramadol in the management of pain. Drug Saf 1996;15:8 29.
21. Shipton EA. Tramadol: present and future. Anesth Intensive Care 2000;28:36374.

APA	Cekic B, Ufuk DOĞAN B, GEZE SAATÇI Ş, ERTÜRK E, BEŞİR A (2013). Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. , 74 - 78.
Chicago	Cekic Bahanur,Ufuk DOĞAN Bahanur,GEZE SAATÇI ŞÜKRAN,ERTÜRK Engin,BEŞİR Ahmet Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. (2013): 74 - 78.
MLA	Cekic Bahanur,Ufuk DOĞAN Bahanur,GEZE SAATÇI ŞÜKRAN,ERTÜRK Engin,BEŞİR Ahmet Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. , 2013, ss.74 - 78.
AMA	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. . 2013; 74 - 78.
Vancouver	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. . 2013; 74 - 78.
IEEE	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A "Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery." , ss.74 - 78, 2013.
ISNAD	Cekic, Bahanur vd. "Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery". (2013), 74-78.

APA	Cekic B, Ufuk DOĞAN B, GEZE SAATÇI Ş, ERTÜRK E, BEŞİR A (2013). Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. European Journal of General Medicine, 10(2), 74 - 78.
Chicago	Cekic Bahanur,Ufuk DOĞAN Bahanur,GEZE SAATÇI ŞÜKRAN,ERTÜRK Engin,BEŞİR Ahmet Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. European Journal of General Medicine 10, no.2 (2013): 74 - 78.
MLA	Cekic Bahanur,Ufuk DOĞAN Bahanur,GEZE SAATÇI ŞÜKRAN,ERTÜRK Engin,BEŞİR Ahmet Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. European Journal of General Medicine, vol.10, no.2, 2013, ss.74 - 78.
AMA	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. European Journal of General Medicine. 2013; 10(2): 74 - 78.
Vancouver	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery. European Journal of General Medicine. 2013; 10(2): 74 - 78.
IEEE	Cekic B,Ufuk DOĞAN B,GEZE SAATÇI Ş,ERTÜRK E,BEŞİR A "Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery." European Journal of General Medicine, 10, ss.74 - 78, 2013.
ISNAD	Cekic, Bahanur vd. "Comparison of the postoperative analgesic effects of wound ınfiltration with tramadol and levobupivacaine in children undergoing ınguinal hernia and undescended testis surgery". European Journal of General Medicine 10/2 (2013), 74-78.