Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life

kılıçarslan, ayşegül; Eser, Filiz; Bodur, Hatice; garip, yesim

Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life

Yeşim GARİP, (Başak Tıp Merkezi, Fiziksel Tıp ve Rehabilitasyon, Bölümü Ankara, Türkiye)

Filiz ESER, (Ankara Numune Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Ankara, Türkiye)

Ayşegül KILIÇARSLAN, (Ankara Numune Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Ankara, Türkiye)

Hatice BODUR (Ankara Numune Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Ankara, Türkiye)

Archives of Rheumatology

2 0

Yıl: 2015 Cilt: 30 Sayı: 3 Sayfa Aralığı: 231 - 237 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life

Öz:

Objectives: This study aims to investigate neuropathic pain in rheumatologic disorders including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and osteoarthritis (OA) using PainDETECT and to determine its effect on the quality of life in terms of disease activity, functional status, social and emotional functioning. Patients and methods: A total of 150 patients (66 males, 84 females; mean age 48.44±12.22 years; range 25 to 65 years) were included in the study. Of these patients, 50 had OA, 50 had RA, and 50 had AS. Control group consisted of 50 healthy subjects (20 males, 30 females; mean age 48.36±12.68 years; range 25 to 65 years). OA severity was evaluated by Western Ontario and McMasters Universities Index of Osteoarthritis. In RA patients, Disease Activity Score-28 was used for measuring disease activity, and Stanford Health Assessment Questionnaire for functional status. In AS patients, disease activity was assessed by Bath Ankylosing Spondylitis Disease Activity Index and functional status by Bath Ankylosing Spondylitis Functional Index. Neuropathic pain was determined by PainDETECT questionnaire and quality of life by Nottingham Health Profile. Results: Prevalence of neuropathic pain was 44% in OA, 28% in AS, and 18% in RA patients. Compared with control patients, prevalence was higher in OA [Odds ratio=12.46 95% confidence interval (3.89-39.85)] (p=0.00) and AS patients [Odds ratio=4.47 95% confidence interval (1.36-14.76)] (p=0.009). In OA patients, PainDETECT was correlated with Western Ontario and McMasters Universities Index of Osteoarthritis (p=0.00). In all of the patient groups, PainDETECT was correlated with Nottingham Health Profile (p=0.00). Physical mobility subgroup showed the strongest correlation with PainDETECT. Conclusion: Our study demonstrated that neuropathic pain is strongly associated with quality of life in terms of physical mobility, energy, sleep, and social and emotional functions. The disease with highest prevalence of neuropathic pain was OA. A better understanding of neuropathic pain mechanisms in rheumatic diseases will help us find more effective treatment strategies.

Anahtar Kelime:

Konular: Romatoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	garip y, Eser F, kılıçarslan a, Bodur H (2015). Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. , 231 - 237.
Chicago	garip yesim,Eser Filiz,kılıçarslan ayşegül,Bodur Hatice Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. (2015): 231 - 237.
MLA	garip yesim,Eser Filiz,kılıçarslan ayşegül,Bodur Hatice Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. , 2015, ss.231 - 237.
AMA	garip y,Eser F,kılıçarslan a,Bodur H Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. . 2015; 231 - 237.
Vancouver	garip y,Eser F,kılıçarslan a,Bodur H Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. . 2015; 231 - 237.
IEEE	garip y,Eser F,kılıçarslan a,Bodur H "Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life." , ss.231 - 237, 2015.
ISNAD	garip, yesim vd. "Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life". (2015), 231-237.

APA	garip y, Eser F, kılıçarslan a, Bodur H (2015). Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. Archives of Rheumatology, 30(3), 231 - 237.
Chicago	garip yesim,Eser Filiz,kılıçarslan ayşegül,Bodur Hatice Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. Archives of Rheumatology 30, no.3 (2015): 231 - 237.
MLA	garip yesim,Eser Filiz,kılıçarslan ayşegül,Bodur Hatice Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. Archives of Rheumatology, vol.30, no.3, 2015, ss.231 - 237.
AMA	garip y,Eser F,kılıçarslan a,Bodur H Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. Archives of Rheumatology. 2015; 30(3): 231 - 237.
Vancouver	garip y,Eser F,kılıçarslan a,Bodur H Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life. Archives of Rheumatology. 2015; 30(3): 231 - 237.
IEEE	garip y,Eser F,kılıçarslan a,Bodur H "Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life." Archives of Rheumatology, 30, ss.231 - 237, 2015.
ISNAD	garip, yesim vd. "Prevalence of Neuropathic Pain in Rheumatic Disorders: Association With Disease Activity, Functional Status and Quality of Life". Archives of Rheumatology 30/3 (2015), 231-237.