The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study

Mollamahmutoglu, Leyla; Danisman, Nuri; Kahyaoglu, Serkan; KAHYAOĞLU, İnci

The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study

İnci KAHYAOĞLU, (Ufuk Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Serkan KAHYAOĞLU, (Boş)

Leyla MOLLAMAHMUTOĞLU, (Boş)

Nuri DANIŞMAN (Dr. Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Cumhuriyet Tıp Dergisi (ELEKTRONİK)

2 0

Yıl: 2012 Cilt: 34 Sayı: 4 Sayfa Aralığı: 447 - 453 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study

Öz:

Amaç. Maternal kronik demir eksikliği anemisinin preterm eylem, düşük doğum ağırlığı veintrauterin gelişme geriliği ile ilişkili olduğu bulunmuştur. Maternal aneminin doğum sırasındatransplasental fetal oksijenizasyonu üzerine olumsuz etkileri henüz çalışılmış değildir. Yöntem.Spontan doğum eylemi başlayan, hemoglobin değeri 9,5gr/dL altında olan 16sı anemik toplam 32term gebe çalışmaya dahil edilmiştir. Doğumdan hemen sonra arteriyel kord kanı örnekleritoplanmıştır. Neonatal Apgar skorları, doğum ağırlıkları ve umbilikal kord pH, PaO2, PaCO2, O2saturasyonu ve HCO3 değerleri kaydedilmiştir. Bulgular. Anemik ve anemik olmayan hastalarınortalama hemoglobin değerleri sırasıyla 7,69±1,14gr/dL ve 10,5±0,67gr/dLdir. Anemik olmayanhastaların neonatal kord kanı PaO2 ve O2 satürasyonu değerleri anemik hastalardan anlamlıderecede daha yüksek bulunmuştur (PaO2 için 84,3 vs. 41,3mmHg ve O2 satürasyonu için %69,5vs. %42,6 , sırasıyla). Anemik ve anemik olmayan hastaların kord kanı PaCO2, pH ve HCO3değerleri arasında fark bulunamamıştır. Sonuç. Her ne kadar, 9,5gr/dLnin altındaki üçüncütrimester maternal hemoglobin seviyesi neonatal kord kanı PaO2 ve O2 satürasyonunda azalmayasebep olsa da, ciddi anemi dışında genel olarak neonatal hipoksemiye yol açmaz. Maternal demireksikliği anemisinin fetüsün transplasental oksij en transportu ve neonatal asit-baz dengesi üzerinemuhtemel etkileri, neonatal hipokseminin yenidoğanın fizyolojik durumuna uzun ve kısa dönemliklinik etkilerinin araştırıldığı çalışmalarla açıklığa kavuşturulmalıdır.

Anahtar Kelime:

Konular: Cerrahi

Maternal demir eksikliği anemisinin derecesi ile f etal neonatal hipoksemi arasındaki ilişki: Kesitsel bir çalışma

Öz:

Aim. Chronic maternal iron deficiency anemia has been found to be related with preterm delivery,low birth weight and intrauterine growth retardation. The potential detrimental effects of maternalanemia on the transplacental fetal oxygen extraction during labor have not been investigated yet.Method. Upon the spontaneous initiation of delivery among 32 term pregnant women, half ofthem with hemoglobin values lower than 9.5gr/dL as anemic group, have been included to thestudy. Arterial cord blood samples have been collected immediately after delivery. Neonatal Apgarscores, birth weight and cord blood analysis of pH, PaO2, PaCO2, O2 saturation and HCO3 havebeen recorded. Results. The mean hemoglobin levels of the anemic and non-anemic patients were7.69±1.14 gr/dL and 10.5 ±0.67gr/dL respectively. Neonatal cord blood PaO2 and O2 saturation ofthe non-anemic patients were significantly higher than anemic patients (84.3 vs. 41.3 mmHg forPaO2 and 69.5% vs. 42.6% for O2 saturation respectively). No significant difference in cord bloodPaCO2, pH and HCO3 levels were found between anemic and non anemic ones. Conclusion.Although third trimester maternal iron deficiency anemia decreases neonatal cord blood PaO2 andO2 saturation levels; apart from severe ones, it does not result in neonatal hypoxemia generally.The possible effects of maternal iron deficiency anemia that can deteriorate transplacental oxygentransport to the fetus and neonatal acid-base status of the newborn should be clarified by furtherstudies based on the short and long term clinical results of neonatal hypoxemia in the newborn sphysiological state.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KAHYAOĞLU İ, Kahyaoglu S, Mollamahmutoglu L, Danisman N (2012). The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. , 447 - 453.
Chicago	KAHYAOĞLU İnci,Kahyaoglu Serkan,Mollamahmutoglu Leyla,Danisman Nuri The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. (2012): 447 - 453.
MLA	KAHYAOĞLU İnci,Kahyaoglu Serkan,Mollamahmutoglu Leyla,Danisman Nuri The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. , 2012, ss.447 - 453.
AMA	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. . 2012; 447 - 453.
Vancouver	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. . 2012; 447 - 453.
IEEE	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N "The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study." , ss.447 - 453, 2012.
ISNAD	KAHYAOĞLU, İnci vd. "The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study". (2012), 447-453.

APA	KAHYAOĞLU İ, Kahyaoglu S, Mollamahmutoglu L, Danisman N (2012). The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. Cumhuriyet Tıp Dergisi (ELEKTRONİK), 34(4), 447 - 453.
Chicago	KAHYAOĞLU İnci,Kahyaoglu Serkan,Mollamahmutoglu Leyla,Danisman Nuri The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. Cumhuriyet Tıp Dergisi (ELEKTRONİK) 34, no.4 (2012): 447 - 453.
MLA	KAHYAOĞLU İnci,Kahyaoglu Serkan,Mollamahmutoglu Leyla,Danisman Nuri The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. Cumhuriyet Tıp Dergisi (ELEKTRONİK), vol.34, no.4, 2012, ss.447 - 453.
AMA	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. Cumhuriyet Tıp Dergisi (ELEKTRONİK). 2012; 34(4): 447 - 453.
Vancouver	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study. Cumhuriyet Tıp Dergisi (ELEKTRONİK). 2012; 34(4): 447 - 453.
IEEE	KAHYAOĞLU İ,Kahyaoglu S,Mollamahmutoglu L,Danisman N "The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study." Cumhuriyet Tıp Dergisi (ELEKTRONİK), 34, ss.447 - 453, 2012.
ISNAD	KAHYAOĞLU, İnci vd. "The relationship between the degree of maternal iron deficiency anemia and fetal neonatal hypoxemia: A cross-sectional study". Cumhuriyet Tıp Dergisi (ELEKTRONİK) 34/4 (2012), 447-453.