The association between platelet/lymphocyte ratio and coronary artery disease severity

Kaya, Hasan; Akyüz, Abdurrahman; YILDIZ, Abdulkadir; AYDIN, MESUT; alan, sait; Yüksel, Murat; POLAT, Nihat; ACET, Halit; OYLUMLU, Mustafa; BILIK, MEHMET ZIHNI

The association between platelet/lymphocyte ratio and coronary artery disease severity

Murat YÜKSEL, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Abdulkadir YILDIZ, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Mustafa OYLUMLU, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Abdurrahman AKYÜZ, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Mesut AYDIN, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Hasan KAYA, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Halit ACET, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Nihat POLAT, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Mehmet Zihni BİLİK, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Sait ALAN (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

The Anatolian Journal of Cardiology

1 0

Yıl: 2015 Cilt: 15 Sayı: 8 Sayfa Aralığı: 640 - 647 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The association between platelet/lymphocyte ratio and coronary artery disease severity

Öz:

Objective: In this study, we aimed to explore the association between platelet-to-lymphocyte ratio (PLR) and the severity of atherosclerosis in coronary artery disease (CAD). Methods: Clinical and laboratory data of 388 patients who underwent coronary angiography were evaluated retrospectively. Gensini score, which indicates the severity of atherosclerosis, was calculated for all of the patients. Patients with CAD were categorized as mild and severe atherosclerosis, according to their Gensini score. Eighty patients with normal coronary arteries formed the control group. Mean PLR values of the three study groups were compared. Also, PLR value was tested for whether it showed a positive correlation with Gensini score. Results: The mean PLR of the severe atherosclerosis group was significantly higher than that of the mild atherosclerosis and controls groups (p<0.001). Also, PLR was positively correlated with Gensini score in CAD patients. A cut-off value of 111 for PLR predicted severe atherosclerosis with 61% sensitivity and 59% specificity. Pre-procedural PLR level was found to be independently associated with Gensini score, together with WBC, age, and low HDL level, in the multivariate analysis. Conclusion: Our study suggests that high PLR appears to be additive to conventional risk factors and commonly used biomarkers in predicting severe atherosclerosis.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Yüksel M, YILDIZ A, OYLUMLU M, Akyüz A, AYDIN M, Kaya H, ACET H, POLAT N, BILIK M, alan s (2015). The association between platelet/lymphocyte ratio and coronary artery disease severity. , 640 - 647.
Chicago	Yüksel Murat,YILDIZ Abdulkadir,OYLUMLU Mustafa,Akyüz Abdurrahman,AYDIN MESUT,Kaya Hasan,ACET Halit,POLAT Nihat,BILIK MEHMET ZIHNI,alan sait The association between platelet/lymphocyte ratio and coronary artery disease severity. (2015): 640 - 647.
MLA	Yüksel Murat,YILDIZ Abdulkadir,OYLUMLU Mustafa,Akyüz Abdurrahman,AYDIN MESUT,Kaya Hasan,ACET Halit,POLAT Nihat,BILIK MEHMET ZIHNI,alan sait The association between platelet/lymphocyte ratio and coronary artery disease severity. , 2015, ss.640 - 647.
AMA	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s The association between platelet/lymphocyte ratio and coronary artery disease severity. . 2015; 640 - 647.
Vancouver	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s The association between platelet/lymphocyte ratio and coronary artery disease severity. . 2015; 640 - 647.
IEEE	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s "The association between platelet/lymphocyte ratio and coronary artery disease severity." , ss.640 - 647, 2015.
ISNAD	Yüksel, Murat vd. "The association between platelet/lymphocyte ratio and coronary artery disease severity". (2015), 640-647.

APA	Yüksel M, YILDIZ A, OYLUMLU M, Akyüz A, AYDIN M, Kaya H, ACET H, POLAT N, BILIK M, alan s (2015). The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology, 15(8), 640 - 647.
Chicago	Yüksel Murat,YILDIZ Abdulkadir,OYLUMLU Mustafa,Akyüz Abdurrahman,AYDIN MESUT,Kaya Hasan,ACET Halit,POLAT Nihat,BILIK MEHMET ZIHNI,alan sait The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology 15, no.8 (2015): 640 - 647.
MLA	Yüksel Murat,YILDIZ Abdulkadir,OYLUMLU Mustafa,Akyüz Abdurrahman,AYDIN MESUT,Kaya Hasan,ACET Halit,POLAT Nihat,BILIK MEHMET ZIHNI,alan sait The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology, vol.15, no.8, 2015, ss.640 - 647.
AMA	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology. 2015; 15(8): 640 - 647.
Vancouver	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology. 2015; 15(8): 640 - 647.
IEEE	Yüksel M,YILDIZ A,OYLUMLU M,Akyüz A,AYDIN M,Kaya H,ACET H,POLAT N,BILIK M,alan s "The association between platelet/lymphocyte ratio and coronary artery disease severity." The Anatolian Journal of Cardiology, 15, ss.640 - 647, 2015.
ISNAD	Yüksel, Murat vd. "The association between platelet/lymphocyte ratio and coronary artery disease severity". The Anatolian Journal of Cardiology 15/8 (2015), 640-647.