Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio

Öz:

BSTRACT Objective: The neutrophil/lymphocyte ratio (NLR), the platelet/lymphocyte ratio (PLR), and uric acid (UA) are inflammatory markers in cardiovascular disease. However, there are not enough data on infarct-related artery (IRA) patency in ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of NLR, PLR, and UA with IRA patency before percutaneous coronary intervention (PCI) in STEMI. Methods: The study was designed as a retrospective study. Three hundred and twenty-four consecutive patients with STEMI were divided into two groups according to pre-PCI Thrombolysis in Myocardial Infarction flow grade (TIMI). Patients with a TIMI flow grade of into the spontaneous reperfusion (SR) group, while patients with TIMI flow grade of 0, 1 and 2 were placed into the non-SR group. The χ2and independentsamples t-test, Mann-Whitney U test, multivariate logistic regression analysis, and receiver-operator characteristic (ROC) curve analysis were used for the statistical analysis. Results: PLR, NLR, and UA values in the SR group were lower than in the non-SR group (p<0.004, p<0.001, p<0.001, respectively). In the multivariate analysis, serum UA level and PLR were found to be independent predictors of pre-PCI IRA patency. In the ROC curve analysis, PLR >190, UA>5.75 mg/dL, and NLR>4.2 predicted non-SR. The sensitivity and specificity of the association between low IRA TIMI flow grade and PLR were 88% and 84%, 72% and 66% for UA, and 74% and 44% for NLR, respectively. Conclusion: We determined that PLR and UA are novel predictors of IRA patency before PCI. We suggest that PLR and UA may be used in riskstratifying STEMI. (

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Konular: Kalp ve Kalp Damar Sistemi

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APA	ACET H, ERTAŞ F, AKIL M, ozyurtlu f, YILDIZ A, POLAT N, BILIK M, AYDIN M, OYLUMLU M, Kaya H, Yüksel M, Akyüz A, AYÇİÇEK H, alan s, TOPRAK N (2015). Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. , 648 - 656.
Chicago	ACET Halit,ERTAŞ Faruk,AKIL Mehmet Ata,ozyurtlu ferhat,YILDIZ Abdulkadir,POLAT Nihat,BILIK MEHMET ZIHNI,AYDIN MESUT,OYLUMLU Mustafa,Kaya Hasan,Yüksel Murat,Akyüz Abdurrahman,AYÇİÇEK Hilal,alan sait,TOPRAK Nizamettin Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. (2015): 648 - 656.
MLA	ACET Halit,ERTAŞ Faruk,AKIL Mehmet Ata,ozyurtlu ferhat,YILDIZ Abdulkadir,POLAT Nihat,BILIK MEHMET ZIHNI,AYDIN MESUT,OYLUMLU Mustafa,Kaya Hasan,Yüksel Murat,Akyüz Abdurrahman,AYÇİÇEK Hilal,alan sait,TOPRAK Nizamettin Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. , 2015, ss.648 - 656.
AMA	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. . 2015; 648 - 656.
Vancouver	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. . 2015; 648 - 656.
IEEE	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N "Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio." , ss.648 - 656, 2015.
ISNAD	ACET, Halit vd. "Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio". (2015), 648-656.

APA	ACET H, ERTAŞ F, AKIL M, ozyurtlu f, YILDIZ A, POLAT N, BILIK M, AYDIN M, OYLUMLU M, Kaya H, Yüksel M, Akyüz A, AYÇİÇEK H, alan s, TOPRAK N (2015). Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology, 15(8), 648 - 656.
Chicago	ACET Halit,ERTAŞ Faruk,AKIL Mehmet Ata,ozyurtlu ferhat,YILDIZ Abdulkadir,POLAT Nihat,BILIK MEHMET ZIHNI,AYDIN MESUT,OYLUMLU Mustafa,Kaya Hasan,Yüksel Murat,Akyüz Abdurrahman,AYÇİÇEK Hilal,alan sait,TOPRAK Nizamettin Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology 15, no.8 (2015): 648 - 656.
MLA	ACET Halit,ERTAŞ Faruk,AKIL Mehmet Ata,ozyurtlu ferhat,YILDIZ Abdulkadir,POLAT Nihat,BILIK MEHMET ZIHNI,AYDIN MESUT,OYLUMLU Mustafa,Kaya Hasan,Yüksel Murat,Akyüz Abdurrahman,AYÇİÇEK Hilal,alan sait,TOPRAK Nizamettin Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology, vol.15, no.8, 2015, ss.648 - 656.
AMA	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology. 2015; 15(8): 648 - 656.
Vancouver	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology. 2015; 15(8): 648 - 656.
IEEE	ACET H,ERTAŞ F,AKIL M,ozyurtlu f,YILDIZ A,POLAT N,BILIK M,AYDIN M,OYLUMLU M,Kaya H,Yüksel M,Akyüz A,AYÇİÇEK H,alan s,TOPRAK N "Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio." The Anatolian Journal of Cardiology, 15, ss.648 - 656, 2015.
ISNAD	ACET, Halit vd. "Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio". The Anatolian Journal of Cardiology 15/8 (2015), 648-656.