Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome

Yüksel, Murat; SOYDİNÇ, Serdar; OYLUMLU, Muhammed; AYDIN, MESUT; Akyüz, Abdurrahman; ACET, Halit; OYLUMLU, Mustafa; BILIK, MEHMET ZIHNI; YILDIZ, Abdulkadir; POLAT, Nihat

Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome

Mustafa OYLUMLU, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Abdulkadir YILDIZ, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Muhammed OYLUMLU, (Dumlupınar Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Kütahya, Türkiye)

Murat YÜKSEL, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Nihat POLAT, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Mehmet Zihni BİLİK, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Abdurrahman AKYÜZ, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Mesut AYDIN, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Halit ACET, (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

Serdar SOYDİNÇ (Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır Türkiye)

The Anatolian Journal of Cardiology

4 2

Yıl: 2015 Cilt: 15 Sayı: 4 Sayfa Aralığı: 277 - 283 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome

Öz:

Objective: Platelets and inflammatory cells are vital elements of acute coronary syndromes (ACS). Recent studies have shown that the platelet-to-lymphocyte ratio (PLR) is associated with several malignancies; however, there are not enough data in cardiovascular diseases. Therefore,the aim of this study was to explore the association between PLR and in-hospital mortality in patients with ACS.Methods: We retrospectively collected patients with ACS undergoing coronary angiography. Total and differential leukocyte counts were mea-sured by an automated hematology analyzer.Results: This study is single-centered and observational. In total, 587 patients with a mean age of 61.8±13.1 years (68.4% male) were enrolledin the study. Patients were divided into 3 tertiles based on PLR levels. In-hospital mortality was significantly higher among patients in the upperPLR tertile when compared with the middle and lower PLR tertile groups [29 (14.8%) vs. 17 (8.7%) and 2 (1.0%); p<0.001]. In the multiple logisticregression analysis, a high level of PLR was an independent predictor of in-hospital mortality, together with age, total leukocyte count, andcreatinine. Using a cutoff point of 142, the PLR predicted in-hospital mortality with a sensitivity of 69% and specificity of 63%.Conclusion: Different from other inflammatory markers and assays, PLR is an inexpensive and readily available biomarker that may be usefulfor cardiac risk stratification in patients with ACS.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	OYLUMLU M, YILDIZ A, OYLUMLU M, Yüksel M, POLAT N, BILIK M, Akyüz A, AYDIN M, ACET H, SOYDİNÇ S (2015). Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. , 277 - 283.
Chicago	OYLUMLU Mustafa,YILDIZ Abdulkadir,OYLUMLU Muhammed,Yüksel Murat,POLAT Nihat,BILIK MEHMET ZIHNI,Akyüz Abdurrahman,AYDIN MESUT,ACET Halit,SOYDİNÇ Serdar Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. (2015): 277 - 283.
MLA	OYLUMLU Mustafa,YILDIZ Abdulkadir,OYLUMLU Muhammed,Yüksel Murat,POLAT Nihat,BILIK MEHMET ZIHNI,Akyüz Abdurrahman,AYDIN MESUT,ACET Halit,SOYDİNÇ Serdar Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. , 2015, ss.277 - 283.
AMA	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. . 2015; 277 - 283.
Vancouver	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. . 2015; 277 - 283.
IEEE	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S "Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome." , ss.277 - 283, 2015.
ISNAD	OYLUMLU, Mustafa vd. "Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome". (2015), 277-283.

APA	OYLUMLU M, YILDIZ A, OYLUMLU M, Yüksel M, POLAT N, BILIK M, Akyüz A, AYDIN M, ACET H, SOYDİNÇ S (2015). Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. The Anatolian Journal of Cardiology, 15(4), 277 - 283.
Chicago	OYLUMLU Mustafa,YILDIZ Abdulkadir,OYLUMLU Muhammed,Yüksel Murat,POLAT Nihat,BILIK MEHMET ZIHNI,Akyüz Abdurrahman,AYDIN MESUT,ACET Halit,SOYDİNÇ Serdar Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. The Anatolian Journal of Cardiology 15, no.4 (2015): 277 - 283.
MLA	OYLUMLU Mustafa,YILDIZ Abdulkadir,OYLUMLU Muhammed,Yüksel Murat,POLAT Nihat,BILIK MEHMET ZIHNI,Akyüz Abdurrahman,AYDIN MESUT,ACET Halit,SOYDİNÇ Serdar Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. The Anatolian Journal of Cardiology, vol.15, no.4, 2015, ss.277 - 283.
AMA	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. The Anatolian Journal of Cardiology. 2015; 15(4): 277 - 283.
Vancouver	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. The Anatolian Journal of Cardiology. 2015; 15(4): 277 - 283.
IEEE	OYLUMLU M,YILDIZ A,OYLUMLU M,Yüksel M,POLAT N,BILIK M,Akyüz A,AYDIN M,ACET H,SOYDİNÇ S "Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome." The Anatolian Journal of Cardiology, 15, ss.277 - 283, 2015.
ISNAD	OYLUMLU, Mustafa vd. "Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome". The Anatolian Journal of Cardiology 15/4 (2015), 277-283.