The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability

BOSTAN, Mehmet; KOCAMAN, Sinan Altan; ÇANĞA, Aytun; Durakoglugil, Murtaza Emre; AKDOĞAN, Remzi Adnan; RAKICI, Halil; İLHAN, Gökhan; DURAKOĞLUGİL, Tuğba; Ergül, Elif

The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability

Murtaza Emre DURAKOĞLUGİL, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Aytun ÇANĞA, (Rize Eğitim ve Araştırma Hastanesi, Kardiyoloji Bölümü, Rize, Türkiye)

Sinan Altan KOCAMAN, (Rize Eğitim ve Araştırma Hastanesi, Kardiyoloji Bölümü, Rize, Türkiye)

Remzi Adnan AKDOĞAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Gastroenteroloji Kliniği, Rize, Türkiye)

Tuğba DURAKOĞLUGİL, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim, Rize, Türkiye)

Elif ERGÜL, (Rize Eğitim ve Araştırma Hastanesi, Kardiyoloji Bölümü, Rize, Türkiye)

Halil RAKICI, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Gastroenteroloji Kliniği, Rize, Türkiye)

Gökhan İLHAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kalp ve Damar Cerrahisi Anabilim Dalı, Rize, Türkiye)

Mehmet BOSTAN (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Anadolu Kardiyoloji Dergisi

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Yıl: 2014 Cilt: 14 Sayı: 6 Sayfa Aralığı: 525 - 530 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability

Öz:

Objective: Irritable bowel syndrome (IBS), a subgroup of functional somatic disorders, may be associated with autonomic dysfunction (AD).Heart rate variability (HRV), a measure of autonomic dysfunction, may predict survival. The aim of this study was to investigate the effect of IBSon HRV parameters, carotid intima-media thickness (CIMT) and carotid-femoral pulse wave velocity (cf-PWV) as surrogates of AD, subclinicalatherosclerosis and arterial stiffness, respectively.Methods: Our study was cross-sectional and observational. Thirty consecutive patients with IBS and 30 control participants underwent 24-hourHolter monitoring, cf-PWV assessment and CIMT measurement. The diagnosis of IBS was based on Rome III criteria. There were 24 patientswith IBS-Constipation (80%), 4 patients with IBS-Diarrhea (13.3%), and 2 patients with IBS-Mixed (6.7%) in IBS group. Student t-test and χ2 testwere utilized in order to compare continuous and categorical variables between two groups, respectively.Results: Biochemical parameters did not differ between groups except for slightly increased creatinine in patients with IBS. cf-PWV and CIMTvalues were similar between groups. SDNN index and RMSSD were significantly impaired in patients with IBS compared to controls. Frequencyanalyses revealed lower LF, HF, and VLF in subjects with IBS.Conclusion: We demonstrated decreased parasympathetic modulation in patients with constipation predominant IBS. However, we could notdemonstrate any changes in vascular structure and functions measured by carotid intima-media thickness and pulse wave velocity. Our resultsdo not support accelerated atherosclerosis in IBS population (Anadolu

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Durakoglugil M, ÇANĞA A, KOCAMAN S, AKDOĞAN R, DURAKOĞLUGİL T, Ergül E, RAKICI H, İLHAN G, BOSTAN M (2014). The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. , 525 - 530.
Chicago	Durakoglugil Murtaza Emre,ÇANĞA Aytun,KOCAMAN Sinan Altan,AKDOĞAN Remzi Adnan,DURAKOĞLUGİL Tuğba,Ergül Elif,RAKICI Halil,İLHAN Gökhan,BOSTAN Mehmet The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. (2014): 525 - 530.
MLA	Durakoglugil Murtaza Emre,ÇANĞA Aytun,KOCAMAN Sinan Altan,AKDOĞAN Remzi Adnan,DURAKOĞLUGİL Tuğba,Ergül Elif,RAKICI Halil,İLHAN Gökhan,BOSTAN Mehmet The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. , 2014, ss.525 - 530.
AMA	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. . 2014; 525 - 530.
Vancouver	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. . 2014; 525 - 530.
IEEE	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M "The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability." , ss.525 - 530, 2014.
ISNAD	Durakoglugil, Murtaza Emre vd. "The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability". (2014), 525-530.

APA	Durakoglugil M, ÇANĞA A, KOCAMAN S, AKDOĞAN R, DURAKOĞLUGİL T, Ergül E, RAKICI H, İLHAN G, BOSTAN M (2014). The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. Anadolu Kardiyoloji Dergisi, 14(6), 525 - 530.
Chicago	Durakoglugil Murtaza Emre,ÇANĞA Aytun,KOCAMAN Sinan Altan,AKDOĞAN Remzi Adnan,DURAKOĞLUGİL Tuğba,Ergül Elif,RAKICI Halil,İLHAN Gökhan,BOSTAN Mehmet The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. Anadolu Kardiyoloji Dergisi 14, no.6 (2014): 525 - 530.
MLA	Durakoglugil Murtaza Emre,ÇANĞA Aytun,KOCAMAN Sinan Altan,AKDOĞAN Remzi Adnan,DURAKOĞLUGİL Tuğba,Ergül Elif,RAKICI Halil,İLHAN Gökhan,BOSTAN Mehmet The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. Anadolu Kardiyoloji Dergisi, vol.14, no.6, 2014, ss.525 - 530.
AMA	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. Anadolu Kardiyoloji Dergisi. 2014; 14(6): 525 - 530.
Vancouver	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability. Anadolu Kardiyoloji Dergisi. 2014; 14(6): 525 - 530.
IEEE	Durakoglugil M,ÇANĞA A,KOCAMAN S,AKDOĞAN R,DURAKOĞLUGİL T,Ergül E,RAKICI H,İLHAN G,BOSTAN M "The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability." Anadolu Kardiyoloji Dergisi, 14, ss.525 - 530, 2014.
ISNAD	Durakoglugil, Murtaza Emre vd. "The effect of irritable bowel syndrome on carotid intima-mediathickness, pulse wave velocity, and heart rate variability". Anadolu Kardiyoloji Dergisi 14/6 (2014), 525-530.