Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya

DAĞLAR, Duygu; NAAS, Theirry; Seyman, Derya; BAYSAN ÖZHAK, Betil; Ogunc, Dilara; Çolak, Dilek; ÖNGÜT, Gözde; Hazar, Volkan; SEPİN, Nevgün

Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya

Nevgün SEPİN, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Dilara ÖĞÜNÇ, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Gözde ÖNGÜT, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Derya SEYMAN, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Duygu DAĞLAR, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Betil BAYSAN ÖZHAK, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Dilek ÇOLAK, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Volkan HAZAR, (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

Theirry NAAS (Antalya Eğitim ve Araştırma Hastanesi, Antalya, Türkiye)

İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi

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Yıl: 2014 Cilt: 21 Sayı: 4 Sayfa Aralığı: 291 - 293 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya

Öz:

Akut Prekürsör B Hücreli Lenfoblastik Lösemi tanısıyla izlenen 4 yaşındaki bir çocuğun kan kültürü örneğinden imipenem dirençli Klebsiella pneumoniae izole edildi. İzolatın PCR analizi sonuçları VIM ve CTX- M enzimleri açısından pozitif olarak saptandı. Yapılan DNA sekans analizi sonucunda 160bplik bölge blaVIM-1 ile uyumlu olarak bulundu. Hasta siprofloksasin tedavisinin 15. gününde remisyonla taburcu edildi. Bu olguda Akdeniz Üniversitesi Hastanesinde ilk kez saptanan VIM 1 pozitif Klebsiella pneumoniae izolatı sunulmuştur. Farklı direnç paternine sahip bir vaka görüldüğünde, hızlı bir şekilde antibiyotik politikalarını da içeren infeksiyon kontrol önlemleri alınmalıdır.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Antalya'da Akut Lenfoblastik Lösemili Hastada VIM-1 Üreten Klebsiella Pneumoniae'ye Bağlı Gelişen Bakteremi

Öz:

A Klebsiella pneumoniae clinical isolate resistant to imipenem was recovered from blood culture of a 4 years old child with the diagnosis of acute precursor B cell lymphoblastic leukemia. PCR assays of Klebsiella pneumoniae isolate were positive with blaCTX-M and blaVIM genes. Sequence analysis of the 160 bp amplicon matched with blaVIM 1. Patient was discharged on the 15th day of ciprofloxacin theraphy with remission. We report here the first VIM-1 positive Klebsiella pneumoniae isolate case from Akdeniz University Hospital. Urgent and rapid precautions must be preferred including antibiotic policy and infection control practices when the first case with different resistance patern is detected.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SEPİN N, Ogunc D, ÖNGÜT G, Seyman D, DAĞLAR D, BAYSAN ÖZHAK B, Çolak D, Hazar V, NAAS T (2014). Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. , 291 - 293.
Chicago	SEPİN Nevgün,Ogunc Dilara,ÖNGÜT Gözde,Seyman Derya,DAĞLAR Duygu,BAYSAN ÖZHAK Betil,Çolak Dilek,Hazar Volkan,NAAS Theirry Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. (2014): 291 - 293.
MLA	SEPİN Nevgün,Ogunc Dilara,ÖNGÜT Gözde,Seyman Derya,DAĞLAR Duygu,BAYSAN ÖZHAK Betil,Çolak Dilek,Hazar Volkan,NAAS Theirry Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. , 2014, ss.291 - 293.
AMA	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. . 2014; 291 - 293.
Vancouver	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. . 2014; 291 - 293.
IEEE	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T "Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya." , ss.291 - 293, 2014.
ISNAD	SEPİN, Nevgün vd. "Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya". (2014), 291-293.

APA	SEPİN N, Ogunc D, ÖNGÜT G, Seyman D, DAĞLAR D, BAYSAN ÖZHAK B, Çolak D, Hazar V, NAAS T (2014). Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 21(4), 291 - 293.
Chicago	SEPİN Nevgün,Ogunc Dilara,ÖNGÜT Gözde,Seyman Derya,DAĞLAR Duygu,BAYSAN ÖZHAK Betil,Çolak Dilek,Hazar Volkan,NAAS Theirry Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 21, no.4 (2014): 291 - 293.
MLA	SEPİN Nevgün,Ogunc Dilara,ÖNGÜT Gözde,Seyman Derya,DAĞLAR Duygu,BAYSAN ÖZHAK Betil,Çolak Dilek,Hazar Volkan,NAAS Theirry Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, vol.21, no.4, 2014, ss.291 - 293.
AMA	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2014; 21(4): 291 - 293.
Vancouver	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2014; 21(4): 291 - 293.
IEEE	SEPİN N,Ogunc D,ÖNGÜT G,Seyman D,DAĞLAR D,BAYSAN ÖZHAK B,Çolak D,Hazar V,NAAS T "Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya." İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 21, ss.291 - 293, 2014.
ISNAD	SEPİN, Nevgün vd. "Bacteremia due to a VIM-1 Producing Klebsiella Pneumoniae Isolate from an Acute Lymphoblastic Leukemia Patient in Antalya". İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 21/4 (2014), 291-293.