Yıl: 2015 Cilt: 7 Sayı: 3 Sayfa Aralığı: 144 - 148 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Multiple Skleroz ve Beslenme

Öz:
Multiple skleroz, genellikle 20-50 yaşları arasında ortaya çıkan, santral sinir sistemini etkileyen otoimmun kronikbir hastalıktır. Hastalık çoğunlukla ataklar ve remisyonlar ile seyretmektedir. Hastalığın hem patogenezinde hemde tedavisinde beslenmenin rolü olduğu düşünülmektedir. D vitamini yetersizliği görülen coğrafi bölgelerde dahayüksek oranda görülen multiple sklerozun tedavisi için pek çok diyet araştırılmıştır. Allerjensiz, glutensiz diyetler,çoklu doymamış yağ asitlerinin kullanıldığı diyetler veya antioksidan besin öğeleri suplementasyonunun yapıldığıdiyetlerden hiçbirinin etkinliği kanıtlanmamıştır. Multiple sklerozda görme bozuklukları, disfaji, nörojen bağırsakgibi besin hazırlama ve tüketmeyi güçleştiren semptomlar görülebilmektedir. Bunun yanında hareket kısıtlılığındandolayı ağırlık artışı da olabilir. Hastaların hem kaşeksi hem de obezite açısından beslenme durumlarının değerlendi- rilmesi, semptomlara yönelik beslenme tedavileri geliştirilmesi ve yaşam boyu izlenmesi önemlidir.
Anahtar Kelime:

Konular: Cerrahi

Multiple Sclerosis and Nutrition

Öz:
Multiple sclerosis is an autoimmune disease which occurs at the age of 20-50 and affects central nervous system. Attacksand remissions are mostly seen during the disease. It is considered that nutrition plays a role in the pathogenesis andtherapy of this disease. Quite a number of diet have been researched for the treatment of multiple sclerosis which is seenin the geographical areas with lack of vitamin D. Non-allergenic diets, diets without gluten, diets including polyunsatu- rated fatty acids or diets with antioxidant nutrient supplementation have been researched and none of their efficiencyhave been proved. Some symptoms such as visual impairment, dysphagia and neurogenic intestine that make foodpreparation and consumption difficult, can be seen during multiple sclerosis. Apart from this, weight gain can be seendue to limitation of movement. It is important to assess the nutritional status of patients in terms of both cachexia andobesity, to develop a nutritional therapy according to symptoms and to provide patients with the life-long monitoring.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Kidd PM. Multiple sclerosis, an autoimmune inflammatory disease: prospects for its integrative management. Altern Med Rev 2001; 6(6):540-566.
  • 2. Remig VM. Medical Nutrition Therapy for Neurologic Disorders. In: Mahan LK, Escott-Stump S, editors. Krause's Food & Nutrition Therapy. Kanada: Saunders Elsevier; 2008. p. 1093-1094.
  • 3. Brown SJ. The role of vitamin D in multiple sclerosis. Ann Pharmacother 2006; 40(6):1158-1161.
  • 4. Ropper AH, Brown RH. Adams and Victor's Principles of Neurology. 8 ed. New York: McGraw-Hill Professional; 2005.
  • 5. Mark BL, Carson JA. Vitamin D and autoimmune disease-- implications for practice from the multiple sclerosis literature. J Am Diet Assoc 2006; 106(3):418-424.
  • 6. Hayes CE. Vitamin D: a natural inhibitor of multiple sclerosis. Proc Nutr Soc 2000; 59(4):531-535.
  • 7. Swank RL, Lerstad O, Strøm A, Backer J. Multiple sclerosis in rural Norway its geographic and occupational incidence in relation to nutrition. N Engl J Med 1952; 246(19):722-728.
  • 8. Fingas CD, Altinbas A, Schlattjan M, Beilfuss A, Sowa JP, Sydor S, et al. Expression of apoptosis- and vitamin D pathway-related genes in hepatocellular carcinoma. Digestion, 2013; 87(3):176-181.
  • 9. Cantorna MT, Hayes, CE, DeLuca HF. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci USA 1996; 93(15):7861-7864.
  • 10. Mirzaei F, Michels KB, Munger K, O’Reilly E, Chitnis T, Forman MR, et al. Gestational vitamin D and the risk of multiple sclerosis in offspring. Ann Neurol, 2011; 70(1): 30-40.
  • 11. Langer-Gould A, Huang S, Van Den Eeden SK, Gupta, R, Leimpeter, AD, Albers KB, et al. Vitamin D, pregnancy, breastfeeding, and postpartum multiple sclerosis relapses. Arch Neurol 2011; 68(3):310-313.
  • 12. Pozuelo-Moyano B, Benito-León J, Mitchell AJ, HernándezGallego JA. systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of vitamin D in multiple sclerosis. Neuroepidemiology 2013; 40(3):147-153.
  • 13. Schwarz S, Leweling H. Multiple sclerosis and nutrition. Mult Scler 2005; 11(1):24-32.
  • 14. Payne A. Nutrition and diet in the clinical management of multiple sclerosis. J Hum Nutr Diet 2001; 14(5):349-357.
  • 15. Swank RL, Goodwin J. Review of MS patient survival on a Swank low saturated fat diet. Nutrition 2003; 19(2):161-162.
  • 16. Farinotti M, Simi S, Di Pietranton PC, McDowell N, Brait L, Lupo D, Filippini G. Dietary interventions for multiple sclerosis. Cochrane Database Syst Rev 2007; Issue 1. Art. No.: CD004192.
  • 17. Pasquinelli S, Solaro C. Nutritional assessment and malnutrition in multiple sclerosis. Neurol Sci 2008; 29(4):367-369.
  • 18. Timmerman GM, Stuifbergin AK. Eating patterns in women with multiple sclerosis. J Neurosci Nurs 1999; 31(3):152-158.
  • 19. Ehrentheil OF, Schulman MH, Alexander L. Role of food allergy in multiple sclerosis. Neurology 1952; 2(5):412-426.
  • 20. Shor DB-A, Barzilai O, Ram M, Izhaky D, Porat-Katz BS, Chapman J, et al. Gluten Sensitivity in Multiple Sclerosis. Annals of the New York Academy of Sciences, 2009; 1173:343–349.
  • 21. Ashtari F, Jamshidi F, Shoormasti RS, Pourpak Z, Akbari M. Cow’s milk allergy in multiple sclerosis patients. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences. 2013;18(1):62-65.
  • 22. Miller D, Barkhof F, Montalban X, Thompson A, Filippi M. Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis, The Lancet Neurology 2005; 4(5):281-288
  • 23. Lange LS, Shiner M. Small-bowel abnormalities in multiple sclerosis. Lancet 1976; 2(7999):1319-1322.
  • 24. Gupta JK, Ingegno AP, Cook AW, Pertschuk LP. Multiple sclerosis and malabsorption. Am J Gastroenterol 1977; 68(6):560-565.
  • 25. Reynolds EH. Multiple sclerosis and vitamin B12 metabolism. J Neurol Neurosurg Psychiatry 1992; 55(5):339-340.
  • 26. Wade DT, Young CA, Chaudhuri KR, Davidson DLW. A randomised placebo controlled exploratory study of vitamin B-12, lofepramine, and L-phenylalanine (the "Cari Loder regime") in the treatment of multiple sclerosis. J Neurol Neurosurg Psychiatry 2002; 73(3):246-249.
  • 27. Jafarirad S, Siassi F, Harirchian, MH, Amani R, Bitarafan S, Saboor-Yaraghi A. The effect of vitamin a supplementation on biochemical parameters in multiple sclerosis patients. Iran Red Crescent Med J 2013; 15(3):194-198.
  • 28. Bitarafan S, Harirchian MH, Sahraian MA, Keramatipour M, Moghadam NB, Togha M, et al. Impact of vitamin A supplementation on RAR gene expression in multiple sclerosis patients. J Mol Neurosci 2013; 51(2):478-484.
  • 29. Gilgun-Sherki Y, Melamed E, Offen D. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J Neurol 2004; 251(3):261-268.
  • 30. Ferretti G, Bacchetti T, Principi F, Di Ludovico F, Viti B, Angeleri VA, et al. Increased levels of lipid hydroperoxides in plasma of patients with multiple sclerosis: a relationship with paraoxonase activity. Mult Scler 2005; 11(6):677-682.
  • 31. Sanoobar M, Eghtesadi S, Azimi A, Khalili M, Jazayeri S, Gohari R. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with relapsingremitting multiple sclerosis. Int J Neurosci 2013; 123(11):776-782.
  • 32. Leong EM, Semple SJ, Angley M, Siebert W, Petkov J, McKinnon RA. Complementary and alternative medicines and dietary interventions in multiple sclerosis: what is being used in South Australia and why? Complement Ther Med 2009; 17(4):216-223.
APA DEMİR A, yıldız arıganoğlu e (2015). Multiple Skleroz ve Beslenme. , 144 - 148.
Chicago DEMİR Aslıhan,yıldız arıganoğlu emine Multiple Skleroz ve Beslenme. (2015): 144 - 148.
MLA DEMİR Aslıhan,yıldız arıganoğlu emine Multiple Skleroz ve Beslenme. , 2015, ss.144 - 148.
AMA DEMİR A,yıldız arıganoğlu e Multiple Skleroz ve Beslenme. . 2015; 144 - 148.
Vancouver DEMİR A,yıldız arıganoğlu e Multiple Skleroz ve Beslenme. . 2015; 144 - 148.
IEEE DEMİR A,yıldız arıganoğlu e "Multiple Skleroz ve Beslenme." , ss.144 - 148, 2015.
ISNAD DEMİR, Aslıhan - yıldız arıganoğlu, emine. "Multiple Skleroz ve Beslenme". (2015), 144-148.
APA DEMİR A, yıldız arıganoğlu e (2015). Multiple Skleroz ve Beslenme. ORTADOĞU TIP DERGİSİ, 7(3), 144 - 148.
Chicago DEMİR Aslıhan,yıldız arıganoğlu emine Multiple Skleroz ve Beslenme. ORTADOĞU TIP DERGİSİ 7, no.3 (2015): 144 - 148.
MLA DEMİR Aslıhan,yıldız arıganoğlu emine Multiple Skleroz ve Beslenme. ORTADOĞU TIP DERGİSİ, vol.7, no.3, 2015, ss.144 - 148.
AMA DEMİR A,yıldız arıganoğlu e Multiple Skleroz ve Beslenme. ORTADOĞU TIP DERGİSİ. 2015; 7(3): 144 - 148.
Vancouver DEMİR A,yıldız arıganoğlu e Multiple Skleroz ve Beslenme. ORTADOĞU TIP DERGİSİ. 2015; 7(3): 144 - 148.
IEEE DEMİR A,yıldız arıganoğlu e "Multiple Skleroz ve Beslenme." ORTADOĞU TIP DERGİSİ, 7, ss.144 - 148, 2015.
ISNAD DEMİR, Aslıhan - yıldız arıganoğlu, emine. "Multiple Skleroz ve Beslenme". ORTADOĞU TIP DERGİSİ 7/3 (2015), 144-148.