Yıl: 2015 Cilt: 42 Sayı: 4 Sayfa Aralığı: 525 - 527 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Toxic epidermal necrolysis secondary to ceftriaxone use: A case report

Öz:
Toksik epidermal nekrolizis (TEN) nadir görülen, hayatı tehdit eden, ciltte epidermis dermis ayrışması yapan ve haşlanmış deri görünümü veren, genellikle ilaç kullanımı ile ilişkili bir klinik durumdur. Acil servise 71 yaşında erkek hasta ateş, halsizlik, ciltte hiperemik erüpsiyonlar ve büller ile başvurdu. Cilt lezyonları total vücut alanının %70inden fazlaydı. Nikolsky bulgusu pozitifti. Hastaya 3 gün önce pnömoni tanısıyla seftriakson başlanmıştı. Hastada TEN düşünüldü. Kullandığı ilaç kesildi. Uygun destek tedavisi başlandı. Yoğun bakım ünitesine yatırıldı. Hasta 8. günde ciltte epitelizasyon gelişince tabucu edildi. TEN mortalitesi yüksek bir sendrom olup acil serviste erken tanı, sebep olan ilacın erken kesilmesi ve uygun destek tedavisinin verilmesi önemlidir.
Anahtar Kelime:

Konular: Cerrahi

Seftriakson kullanımı sonucu gelişen toksik epidermal nekrolizis: Bir olgu sunumu

Öz:
Toxic epidermal necrolysis (TEN) is a rare, life-threatening condition that is usually associated with medication use and characterized by separation of epidermis and dermis and a scalded skin appearance. A 71-year-old man presented to emergency department with fever, malaise, and hyperemic skin eruptions and bullae. Skin lesions covered more than 70% of total body surface area. Nikolsky sign was positive. He had been begun ceftriaxone for pneumonia before. TEN was considered as the initial diagnosis; the medication he used was stopped, appropriate supportive treatment was begun, and the patient was admitted to intensive care unit. He was discharged on 8th day after skin epithelization occurred. Toxic epidermal necrolysis is a highly fatal syndrome, in which early diagnosis, stopping the offensive drug, and administering appropriate supportive treatment are important components of the management.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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APA İÇER M, ZENGİN Y, GÜNDÜZ E, DURGUN H, ORAK M, ÜSTÜNDAĞ M, GÜLOĞLU C (2015). Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. , 525 - 527.
Chicago İÇER Mustafa,ZENGİN Yılmaz,GÜNDÜZ Ercan,DURGUN HASAN MANSUR,ORAK MURAT,ÜSTÜNDAĞ Mehmet,GÜLOĞLU Cahfer Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. (2015): 525 - 527.
MLA İÇER Mustafa,ZENGİN Yılmaz,GÜNDÜZ Ercan,DURGUN HASAN MANSUR,ORAK MURAT,ÜSTÜNDAĞ Mehmet,GÜLOĞLU Cahfer Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. , 2015, ss.525 - 527.
AMA İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. . 2015; 525 - 527.
Vancouver İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. . 2015; 525 - 527.
IEEE İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C "Toxic epidermal necrolysis secondary to ceftriaxone use: A case report." , ss.525 - 527, 2015.
ISNAD İÇER, Mustafa vd. "Toxic epidermal necrolysis secondary to ceftriaxone use: A case report". (2015), 525-527.
APA İÇER M, ZENGİN Y, GÜNDÜZ E, DURGUN H, ORAK M, ÜSTÜNDAĞ M, GÜLOĞLU C (2015). Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. Dicle Tıp Dergisi, 42(4), 525 - 527.
Chicago İÇER Mustafa,ZENGİN Yılmaz,GÜNDÜZ Ercan,DURGUN HASAN MANSUR,ORAK MURAT,ÜSTÜNDAĞ Mehmet,GÜLOĞLU Cahfer Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. Dicle Tıp Dergisi 42, no.4 (2015): 525 - 527.
MLA İÇER Mustafa,ZENGİN Yılmaz,GÜNDÜZ Ercan,DURGUN HASAN MANSUR,ORAK MURAT,ÜSTÜNDAĞ Mehmet,GÜLOĞLU Cahfer Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. Dicle Tıp Dergisi, vol.42, no.4, 2015, ss.525 - 527.
AMA İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. Dicle Tıp Dergisi. 2015; 42(4): 525 - 527.
Vancouver İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C Toxic epidermal necrolysis secondary to ceftriaxone use: A case report. Dicle Tıp Dergisi. 2015; 42(4): 525 - 527.
IEEE İÇER M,ZENGİN Y,GÜNDÜZ E,DURGUN H,ORAK M,ÜSTÜNDAĞ M,GÜLOĞLU C "Toxic epidermal necrolysis secondary to ceftriaxone use: A case report." Dicle Tıp Dergisi, 42, ss.525 - 527, 2015.
ISNAD İÇER, Mustafa vd. "Toxic epidermal necrolysis secondary to ceftriaxone use: A case report". Dicle Tıp Dergisi 42/4 (2015), 525-527.