Yıl: 2015 Cilt: 12 Sayı: 3 Sayfa Aralığı: 164 - 167 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review

Öz:
Objective: This is a case series and literature review of patients with endometrial serous carcinoma (ESC) in which endocervical curettage (ECC) and CA- 125 measurement were utilized as a diagnostic procedure in preoperative staging. Materials and Methods: The patients were treated in the gynecologic oncology clinic of İstanbul University Faculty of Medicine between January 2005, and January 2015. A total of 37 patients were included in the final analysis. Results: ECC accurately predicted ESC in 22 patients (59.5%). The mean pre-operative serum CA-125 level was 73.24±3.30 IU/mL; pre-operative serum CA-125 levels were elevated above 35 IU/mL in 25 patients (69%). Conclusion: ECC is an acceptable diagnostic tool to predict the presence or absence of cervical involvement in endometrial cancer. On the other hand, its accuracy in specific subgroups requires further analysis in carefully designed prospective studies. Furthermore, pre-operative serum CA-125 levels may be important for management and counseling in the subgroup of women with ESC.
Anahtar Kelime:

Konular: Cerrahi

Endometrial seröz karsinomda endoservikal küretajın ve CA-125 ölçümünün etkinliği: Olgu serisi ve literatür derlemesi

Öz:
Öz Amaç: Bu olgu serisi ve derlemede amaç endometrial seröz karsinom (ESK) hastalarında endoservikal küretajın (ESK) ve kanda CA-125 ölçümünün cerrahi yaklaşım öncesi uygulamalarında etkinliğini araştırmaktır. Gereç ve Yöntem: İstanbul Üniversitesi Tıp Fakültesi nin Jinekolojik Onkoloji Kliniği ne başvurmuş hastalar Ocak 2005 ve Ocak 2015 arası retrospektif olarak taranmış ve son çalışmaya 37 hasta dahil edilmiştir. Bulgular: Endometrial küretaj 22 hastada ESK tanısını koymuştur. Cerrahi yaklaşım öncesi kanda CA-125 seviyesi 73,24±3,30 IU/ml bulunmuştur. Yirmi beş hastanın, CA-125 seviyesi 35 IU/mL nin üzerinde çıkmıştır. Sonuç: Endometrial küretaj, endometrial kanserde servikal yayılmanın varlığının tanısında etkin bir araçtır. Öte yandan endometrial kanserlerin alt gruplarında etkinliğini ölçmede prospektif çalışmalara halen ihtiyaç vardır. Ek olarak, cerrahi yaklaşım öncesi kanda CA-125 ölçümü endometrial seröz karsinom hastalarının yönetiminde katkı sağlayabilir.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA İYİBOZKURT A, DOĞAN Ö, BAŞTU E, SÖZEN H, Vatansever D, Topuz S, BERKMAN S (2015). Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. , 164 - 167.
Chicago İYİBOZKURT Ahmet Cem,DOĞAN Özkan Murat,BAŞTU Ercan,SÖZEN Hamdullah,Vatansever Dogan,Topuz Samet,BERKMAN Sinan Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. (2015): 164 - 167.
MLA İYİBOZKURT Ahmet Cem,DOĞAN Özkan Murat,BAŞTU Ercan,SÖZEN Hamdullah,Vatansever Dogan,Topuz Samet,BERKMAN Sinan Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. , 2015, ss.164 - 167.
AMA İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. . 2015; 164 - 167.
Vancouver İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. . 2015; 164 - 167.
IEEE İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S "Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review." , ss.164 - 167, 2015.
ISNAD İYİBOZKURT, Ahmet Cem vd. "Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review". (2015), 164-167.
APA İYİBOZKURT A, DOĞAN Ö, BAŞTU E, SÖZEN H, Vatansever D, Topuz S, BERKMAN S (2015). Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. Türk Jinekoloji ve Obstetrik Derneği Dergisi, 12(3), 164 - 167.
Chicago İYİBOZKURT Ahmet Cem,DOĞAN Özkan Murat,BAŞTU Ercan,SÖZEN Hamdullah,Vatansever Dogan,Topuz Samet,BERKMAN Sinan Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. Türk Jinekoloji ve Obstetrik Derneği Dergisi 12, no.3 (2015): 164 - 167.
MLA İYİBOZKURT Ahmet Cem,DOĞAN Özkan Murat,BAŞTU Ercan,SÖZEN Hamdullah,Vatansever Dogan,Topuz Samet,BERKMAN Sinan Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. Türk Jinekoloji ve Obstetrik Derneği Dergisi, vol.12, no.3, 2015, ss.164 - 167.
AMA İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. Türk Jinekoloji ve Obstetrik Derneği Dergisi. 2015; 12(3): 164 - 167.
Vancouver İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review. Türk Jinekoloji ve Obstetrik Derneği Dergisi. 2015; 12(3): 164 - 167.
IEEE İYİBOZKURT A,DOĞAN Ö,BAŞTU E,SÖZEN H,Vatansever D,Topuz S,BERKMAN S "Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review." Türk Jinekoloji ve Obstetrik Derneği Dergisi, 12, ss.164 - 167, 2015.
ISNAD İYİBOZKURT, Ahmet Cem vd. "Efficacy of endocervical curettage and CA-125 measurement in endometrial serous carcinoma: A case series and literature review". Türk Jinekoloji ve Obstetrik Derneği Dergisi 12/3 (2015), 164-167.