Acquired hepatocerebral degeneration (AHCD) describes a neurological disorder in thecontext of chronic hepatic failure which is not related to acute encephalopathy and notexplained by an alternative cause. Patients with AHCD may have cognitive deficits, cerebellarfindings, hypo- or hyperkinetic movement disorders, and sometimes myelopathy with typicalmagnetic resonance imaging (MRI) abnormalities, particularly T1 hyperintensity in theinternal pallidum.Here, we report five patients ranging between 45-73 years-old. All had liver disease, four ofthem were diagnosed as chronic liver failure and one had portosystemic shunts secondary toportal vein thrombosis. Presenting neurological symptoms were parkinsonism (4), ataxia (3),postural and action tremor (3) and cognitive deficit (2). MRI findings were compatible withAHCD.This report shows the variability of neurological symptoms in AHCD. Possibility of liverdisease or portosystemic shunts should be kept in mind before diagnosing anyneurodegenerative disease and giving treatments toxic to the liver since neurologicalsymptoms may occur in the presence of normal liver enzymes in some liver diseases causingneurological symptoms.