Yıl: 2015 Cilt: 32 Sayı: 2 Sayfa Aralığı: 361 - 371 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study

Öz:
Amaç: Fokal temporal lob epilepsisinde, nöbet aktivitesinin önceden kestirimini yapabilmekamacıyla nöbet öncesi EEG verisinde interhemisferik korelasyon katsayılarının incelenmesiamaçlanmıştır.Gereç ve Yöntem: Bu retrospektif ön çalışmada İzmir Katip Çelebi Üniversitesi TıpFakültesi Atatürk Eğitim ve Araştırma Hastanesi Nöroloji Anabilim Dalı video-EEGveritabanından alınan veriler kullanılmıştır. 2010 -2013 yılları arasında fokal temporal lobepilepsi tanısı almış hastalardan 31 tanesi rastgele seçilmiş (ortalama yaş 32.3 ± 7.6; 17 kadın)ve toplam 52 nöbet verisi analiz edilmiştir. Herbir nöbet için nöbet öncesi 20 s'lik EEG verisianaliz edilmiştir. Korelasyon katsayılarındaki değişimi gözlemek için nöbet öncesi 20 s'likEEG verisi herbiri 2s olan 10 pencereye bölünerek incelenmiştir. Nöbete en uzak olan pencere1. pencere , nöbete en yakın pencere ise 10. pencere olarak işaretlenmiştir. Herbir pencereiçin, 9 elektot çiftinde interhemisferik Pearson korelasyon katsayıları hesaplanmıştır.Pencereler arasında korelasyon katsayılarının değişkenliği tekrarlayan ölçümlerde ANOVAyöntemi ile analiz edilmiştir.Bulgular: F7T1-F8T2; T1T3-T2T4; FP1F3- FP2F4; C3P3-C4P4 elektrot çiftlerinde Pearsonkorelasyon katsayıları 1. pencereden 10. pencereye doğru anlamlı düşme göstermiştir(p<0.05). Post hoc çoklu karşılaştırmalarında korelasyon katsayıları arasındaki anlamlıfarklılığın ilk iki pencere (0-4 s) ile son üç pencere (14-20 s) arasında olduğu görülmüştür.Sonuç: Bu çalışmanın sonuçları interhemisferik korelasyon katsayılarının EEG sinyallerindeepileptik nöbetleri belirlemek için kullanılabileceğini göstermiştir.
Anahtar Kelime:

Konular: Nörolojik Bilimler

Interhemisferik Korelasyon ve Epileptik Nöbetler Arasında Bir İlişki Var mı? Retrospektif Ön Çalışma

Öz:
Objectives: For the purpose of predicting seizure activities in focal temporal lobe epilepsy weexamined interhemispheric correlation coefficients in pre-ictal EEG data.Materials and Methods: We used video-EEG data obtained from the İzmir Katip ÇelebiUniversity Atatürk Training and Research Hospital Neurology Department database toconduct preliminary retrospective analyses. 31 patients (mean age 32.3 ± 7.6; 17 female)diagnosed with focal temporal lobe epilepsy in 2010-2013 were randomly selected and a totalof 52 seizures were analyzed. 20 sec pre-ictal EEG data were studied for each seizure. Inorder to observe the change in the correlation coefficients 20 sec pre-ictal EEG data weredivided into 10 windows (each 2 sec). The furthest window to the seizure was labeled as 1st window, the closest window to the seizure was labeled as 10th window. InterhemisphericPearson correlation coefficients were computed for each window in 9 electrode pairs. Thevariability of the correlation coefficients between windows was analyzed with RepeatedMeasures of ANOVA.Results: Pearson correlation coefficients decreased significantly from the 1st window to the10th window in the following electrode pairs: F7T1-F8T2; T1T3-T2T4; FP1F3- FP2F4;C3P3-C4P4 (p<0.05). Post hoc multiple comparison analysis revealed that the significantdifference in correlation coefficients was mainly observed between the first two windows (0-4seconds) before seizure onset and the last three windows (14-20 seconds) before seizureonset.Conclusion: The results of the present study suggest that interhemispheric correlation may beapplicable for the detection of epileptic seizures in EEG signals.
Anahtar Kelime:

Konular: Nörolojik Bilimler
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA KOCAASLAN ATLI S, TÜRE H, BAYAZIT T, AKHAN G (2015). Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. , 361 - 371.
Chicago KOCAASLAN ATLI SİBEL,TÜRE HATİCE SABİHA,BAYAZIT Turan Onur,AKHAN GALIP Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. (2015): 361 - 371.
MLA KOCAASLAN ATLI SİBEL,TÜRE HATİCE SABİHA,BAYAZIT Turan Onur,AKHAN GALIP Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. , 2015, ss.361 - 371.
AMA KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. . 2015; 361 - 371.
Vancouver KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. . 2015; 361 - 371.
IEEE KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G "Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study." , ss.361 - 371, 2015.
ISNAD KOCAASLAN ATLI, SİBEL vd. "Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study". (2015), 361-371.
APA KOCAASLAN ATLI S, TÜRE H, BAYAZIT T, AKHAN G (2015). Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. Journal of Neurological Sciences (Turkish), 32(2), 361 - 371.
Chicago KOCAASLAN ATLI SİBEL,TÜRE HATİCE SABİHA,BAYAZIT Turan Onur,AKHAN GALIP Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. Journal of Neurological Sciences (Turkish) 32, no.2 (2015): 361 - 371.
MLA KOCAASLAN ATLI SİBEL,TÜRE HATİCE SABİHA,BAYAZIT Turan Onur,AKHAN GALIP Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. Journal of Neurological Sciences (Turkish), vol.32, no.2, 2015, ss.361 - 371.
AMA KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. Journal of Neurological Sciences (Turkish). 2015; 32(2): 361 - 371.
Vancouver KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study. Journal of Neurological Sciences (Turkish). 2015; 32(2): 361 - 371.
IEEE KOCAASLAN ATLI S,TÜRE H,BAYAZIT T,AKHAN G "Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study." Journal of Neurological Sciences (Turkish), 32, ss.361 - 371, 2015.
ISNAD KOCAASLAN ATLI, SİBEL vd. "Interhemispheric Correlation and Epileptic Seizures: Are They Related? A Preliminary Retrospective Study". Journal of Neurological Sciences (Turkish) 32/2 (2015), 361-371.